Endoscopic submucosal dissection in colorectal neoplasia performed with a waterjet system-assisted knife: higher en-bloc resection rate than conventional technique
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Background/Aims: Colorectal endoscopic submucosal dissection (ESD) is burdened by its associated high risk of adverse events andlong procedure time. Recently, a waterjet-assisted knife was introduced to simplify and speed up the procedure. The aim of this studywas to evaluate the efficacy and safety of waterjet-assisted ESD (WESD) compared to that of the conventional ESD (CESD) technique. Methods: The charts of 254 consecutive patients who underwent colorectal ESD between January 2014 and February 2021 for colorec-tal neoplasms were analyzed. The primary outcome was the en-bloc resection rate. Secondary outcomes were complete and curative re-section rates, the need to switch to a hybrid ESD, procedure speed, the adverse event rates, and the recurrence rates. Results: Approximately 174 neoplasias were considered, of which, 123 were removed by WESD and 51 by CESD. The en-bloc resectionrate was higher in the WESD group (94.3% vs. 84.3%). Complete resection rates and curative resection rates were similar. The need toswitch to a hybrid ESD was greater during CESD (39.2% vs. 13.8%). Procedure speed and adverse event rates were similar. During fol-low-up, one recurrence occurred after a WESD. Conclusions: WESD allows a high rate of en-bloc resections and less frequently requires a rescue switch to the hybrid ESD comparedto CESD.
Abstract
Background/Aims: Colorectal endoscopic submucosal dissection (ESD) is burdened by its associated high risk of adverse events andlong procedure time. Recently, a waterjet-assisted knife was introduced to simplify and speed up the procedure. The aim of this studywas to evaluate the efficacy and safety of waterjet-assisted ESD (WESD) compared to that of the conventional ESD (CESD) technique. Methods: The charts of 254 consecutive patients who underwent colorectal ESD between January 2014 and February 2021 for colorec-tal neoplasms were analyzed. The primary outcome was the en-bloc resection rate. Secondary outcomes were complete and curative re-section rates, the need to switch to a hybrid ESD, procedure speed, the adverse event rates, and the recurrence rates. Results: Approximately 174 neoplasias were considered, of which, 123 were removed by WESD and 51 by CESD. The en-bloc resectionrate was higher in the WESD group (94.3% vs. 84.3%). Complete resection rates and curative resection rates were similar. The need toswitch to a hybrid ESD was greater during CESD (39.2% vs. 13.8%). Procedure speed and adverse event rates were similar. During fol-low-up, one recurrence occurred after a WESD. Conclusions: WESD allows a high rate of en-bloc resections and less frequently requires a rescue switch to the hybrid ESD comparedto CESD.
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