급성과 만성 호산구성 폐렴
Acute and Chronic Eosinophilic Pneumonias
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참고문헌
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초록
급성 호산구성 폐렴은 생명을 위협할 수 있는 호흡부전을 발생시킬 수 있다. 대부분은 스테로이드 치료에 의해서 신속하고 완전하게 회복되고 재발은 드물다. 만성 호산구성 폐렴은 일반적으로 한 달 이상의 증상기간을 가지면서 진행한다. 스테로이드 치료에 반응이 좋으나 재발이 흔하며, 천식과의 연관성이 관찰된다.
Abstract
Although eosinophils may rise to 5-25% of the cells in the bronchoalveolar lavage (BAL) fluid in a variety of conditions, more than 25% eosinophils in BAL fluid strongly suggest one of the eosinophilic pneumonias. Acute eosinophilc pneumonia (AEP) is a sudden and febrile illness that can results in life-threatening respiratory failure, frequently misdiagnosed as severe community-acquired pneumonia. Most patients respond rapidly and completely to glucocorticoids, generally without relapse. Chronic eosinophilic pneumonia (CEP) is a protracted disease of usually more than a month before presentation, with mild to moderate hypoxemia. The disorder is highly responsive to glucocorticoid therapy, but recurs frequent when tapering or after stopping glucocorticoid therapy. Some patients have a history of asthma at diagnosis or develop severe asthma at some time in the follow-up. There are significant relationships between asthma and chronic eosinophilc pneumonia.
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