양성 낭종성 갑상선 결절에 대한 에탄올 절제술의 효과
The Effect of Ethanol Ablation for the Treatment of Benign Cystic Thyroid Nodules
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초록
Kim 등[5]의 연구가 다른 연구들에 비해 비교적 장기간 관찰하였지만 후향적인 연구로 반응을 평가한 기간이 6개월에서 3년으로 일정치 않은 문제점이 있었다. 이러한 문제점은 향후 전향적 연구를 통해 보완되어야 할 것으로 생각한다. 결론적으로 증상이 있거나 미용적인 문제가 있는 갑상선 낭성결절의 치료에 있어 에탄올 절제술은 효과적이며 안전한 치료법이다. 비록 제한적이지만 수술이 어려운 갑상선분화암 재발병소의 치료에도 에탄올 절제술의 이용이 확대되기를 기대한다.
Abstract
Simple aspiration is the initial therapy in patients with the symptomatic benign thyroid cystic nodule, but treatment failure is very common. In patients with recurrent cystic thyroid nodules, ethanol ablation (EA), radiofrequency ablation, or laser ablation can be used to prevent reaccumulation of cystic fluid. EA is simple, cheap and needs no specialized equipment. Kim et al. reported the long-term efficacy and safety of ultrasound-guided percutaneous EA for cystic or predominantly cystic thyroid nodules. They also evaluated the clinical factors associated with treatment failure. Successful ablation was obtained in 31 of 40 (77.5%) patients, and initial large cystic volume was the factor associated with therapeutic failure. The side effect was negligible except transient local pain immediately after the procedure. Although this study had retrospective design and irregular follow-up, it is plausible that EA is a safe and effective therapy for treating cystic or predominantly cystic thyroid nodule.
참고문헌 (10)
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