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Role of endoscopy in patients with achalasia

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Achalasia is an esophageal motility disorder characterized by impaired lower esophageal sphincter relaxation and peristalsis of theesophageal body. With the increasing prevalence of achalasia, interest in the role of endoscopy in its diagnosis, treatment, and monitoringis also growing. The major diagnostic modalities for achalasia include high-resolution manometry, esophagogastroduodenoscopy,and barium esophagography. Endoscopic assessment is important for early diagnosis to rule out diseases that mimic achalasia symptoms,such as pseudo-achalasia, esophageal cancer, esophageal webs, and eosinophilic esophagitis. The major endoscopic characteristicssuggestive of achalasia include a widened esophageal lumen and food residue in the esophagus. Once diagnosed, achalasia can betreated either endoscopically or surgically. The preference for endoscopic treatment is increasing owing to its minimal invasiveness. Botulinum toxins, pneumatic balloon dilation, and peroral endoscopic myotomy (POEM) are important endoscopic treatments. Previousstudies have demonstrated excellent treatment outcomes for POEM, with >95% improvement in dysphagia, making POEM themainstay treatment option for achalasia. Several studies have reported an increased risk of esophageal cancer in patients with achalasia. However, routine endoscopic surveillance remains controversial owing to the lack of sufficient data. Further studies on surveillancemethods and duration are warranted to establish concordant guidelines for the endoscopic surveillance of achalasia.

Abstract

Achalasia is an esophageal motility disorder characterized by impaired lower esophageal sphincter relaxation and peristalsis of theesophageal body. With the increasing prevalence of achalasia, interest in the role of endoscopy in its diagnosis, treatment, and monitoringis also growing. The major diagnostic modalities for achalasia include high-resolution manometry, esophagogastroduodenoscopy,and barium esophagography. Endoscopic assessment is important for early diagnosis to rule out diseases that mimic achalasia symptoms,such as pseudo-achalasia, esophageal cancer, esophageal webs, and eosinophilic esophagitis. The major endoscopic characteristicssuggestive of achalasia include a widened esophageal lumen and food residue in the esophagus. Once diagnosed, achalasia can betreated either endoscopically or surgically. The preference for endoscopic treatment is increasing owing to its minimal invasiveness. Botulinum toxins, pneumatic balloon dilation, and peroral endoscopic myotomy (POEM) are important endoscopic treatments. Previousstudies have demonstrated excellent treatment outcomes for POEM, with >95% improvement in dysphagia, making POEM themainstay treatment option for achalasia. Several studies have reported an increased risk of esophageal cancer in patients with achalasia. However, routine endoscopic surveillance remains controversial owing to the lack of sufficient data. Further studies on surveillancemethods and duration are warranted to establish concordant guidelines for the endoscopic surveillance of achalasia.

참고문헌 (67)

  1. Pomenti S, "Achalasia : diagnosis, management and surveillance", Gastroenterol Clin North Am, 50, pp.721~736 (2021)
  2. Pohl D, "Achalasia : an overview of diagnosis and treatment", J Gastrointestin Liver Dis, 16, pp.297~303 (2007)
  3. Vaezi MF, "ACG clinical guidelines : diagnosis and management of achalasia", Am J Gastroenterol, 115, pp.1393~1411 (2020)
  4. O'Neill OM, "Achalasia : a review of clinical diagnosis, epidemiology, treatment and outcomes", World J Gastroenterol, 19, pp.5806~5812 (2013)
  5. Park W, "Etiology and pathogenesis of achalasia : the current understanding", Am J Gastroenterol, 100, pp.1404~1414 (2005)
  6. Sadowski DC, "Achalasia : incidence, prevalence and survival. A population-based study", Neurogastroenterol Motil, 22, pp.e256~ (2010)
  7. 김은경, "Achalasia in Korea: An Epidemiologic Study Using a National Healthcare Database", Journal of Korean Medical Science, 29(4), pp.576~580 (2014), 대한의학회
  8. Birgisson S, "Achalasia in Iceland, 1952-2002 : an epidemiologic study", Dig Dis Sci, 52, pp.1855~1860 (2007)
  9. Samo S, "Incidence and prevalence of achalasia in central Chicago, 2004-2014, since the widespread use of high-resolution manometry", Clin Gastroenterol Hepatol, 15, pp.366~373 (2017)
  10. Su B, "Using impedance planimetry(EndoFLIP)to evaluate myotomy and predict outcomes after surgery for achalasia", J Gastrointest Surg, 24, pp.964~971 (2020)
  11. Mari A, "Diagnosis and management of achalasia : updates of the last two years", J Clin Med, 10, pp.3607~ (2021)
  12. Gockel I, "Pseudoachalasia : a case series and analysis of the literature", Scand J Gastroenterol, 40, pp.378~385 (2005)
  13. Desai TK, "Association of eosinophilic inflammation with esophageal food impaction in adults", Gastrointest Endosc, 61, pp.795~801 (2005)
  14. Potter JW, "Eosinophilic esophagitis in adults : an emerging problem with unique esophageal features", Gastrointest Endosc, 59, pp.355~361 (2004)
  15. Mandaliya R, "Association of achalasia and eosinophilic esophagitis", Indian J Gastroenterol, 32, pp.54~57 (2013)
  16. Schizas D, "Eosinophilic esophagitis and achalasia : two distinct nosologic entities or a possible etiopathogenic association?", Dig Dis, 39, pp.553~560 (2021)
  17. Japan Esophageal Society, "Descriptive rules for achalasia of the esophagus, June 2012 : 4th edition", Esophagus, 14, pp.275~289 (2017)
  18. Howard PJ, "Five year prospective study of the incidence, clinical features, and diagnosis of achalasia in Edinburgh", Gut, 33, pp.1011~1015 (1992)
  19. Minami H, "New endoscopic indicator of esophageal achalasia : "pinstripe pattern"", PLoS One, 10, pp.e0101833~ (2015)
  20. Iwakiri K, "The appearance of rosette-like esophageal folds("esophageal rosette")in the lower esophagus after a deep inspiration is a characteristic endoscopic finding of primary achalasia", J Gastroenterol, 45, pp.422~425 (2010)
  21. Gomi K, "New endoscopic classification of the cardiac orifice in esophageal achalasia : champagne glass sign", Dig Endosc, 28, pp.645~649 (2016)
  22. Payne WS, "Heller's contribution to the surgical treatment of achalasia of the esophagus. 1914", Ann Thorac Surg, 48, pp.876~881 (1989)
  23. Pasricha PJ, "Effects of intrasphincteric botulinum toxin on the lower esophageal sphincter in piglets", Gastroenterology, 105, pp.1045~1049 (1993)
  24. Pasricha PJ, "Treatment of achalasia with intrasphincteric injection of botulinum toxin. A pilot trial", Ann Intern Med, 121, pp.590~591 (1994)
  25. Pasricha PJ, "Intrasphincteric botulinum toxin for the treatment of achalasia", N Engl J Med, 332, pp.774~778 (1995)
  26. Ramzan Z, "The role of botulinum toxin injection in the management of achalasia", Curr Opin Gastroenterol, 29, pp.468~473 (2013)
  27. Neubrand M, "Long-term results and prognostic factors in the treatment of achalasia with botulinum toxin", Endoscopy, 34, pp.519~523 (2002)
  28. Cuillière C, "Achalasia : outcome of patients treated with intrasphincteric injection of botulinum toxin", Gut, 41, pp.87~92 (1997)
  29. Kolbasnik J, "Long-term efficacy of Botulinum toxin in classical achalasia : a prospective study", Am J Gastroenterol, 94, pp.3434~3439 (1999)
  30. Richter JE, "Management of achalasia : surgery or pneumatic dilation", Gut, 60, pp.869~876 (2011)
  31. van Hoeij FB, "Efficacy and safety of pneumatic dilation in achalasia : a systematic review and meta-analysis", Neurogastroenterol Motil, 31, pp.e13548~ (2019)
  32. Mikaeli J, "Pneumatic balloon dilatation in achalasia : a prospective comparison of safety and efficacy with different balloon diameters", Aliment Pharmacol Ther, 20, pp.431~436 (2004)
  33. Boeckxstaens GE, "Pneumatic dilation versus laparoscopic Heller's myotomy for idiopathic achalasia", N Engl J Med, 364, pp.1807~1816 (2011)
  34. Hulselmans M, "Long-term outcome of pneumatic dilation in the treatment of achalasia", Clin Gastroenterol Hepatol, 8, pp.30~35 (2010)
  35. Vanuytsel T, "Conservative management of esophageal perforations during pneumatic dilation for idiopathic esophageal achalasia", Clin Gastroenterol Hepatol, 10, pp.142~149 (2012)
  36. Yamashita H, "Predictive factors associated with the success of pneumatic dilatation in Japanese patients with primary achalasia : a study using high-resolution manometry", Digestion, 87, pp.23~28 (2013)
  37. Nitesh Pratap, "Achalasia Cardia Subtyping by High-Resolution Manometry Predicts the Therapeutic Outcome of Pneumatic Balloon Dilatation", Journal of Neurogastroenterology and Motility (JNM), 17(1), pp.48~53 (2011), 대한소화기 기능성질환∙운동학회
  38. Eckardt VF, "Predictors of outcome in patients with achalasia treated by pneumatic dilation", Gastroenterology, 103, pp.1732~1738 (1992)
  39. Rohof WO, "Outcomes of treatment for achalasia depend on manometric subtype", Gastroenterology, 144, pp.718~725 (2013)
  40. Inoue H, "Peroral endoscopic myotomy(POEM)for esophageal achalasia", Endoscopy, 42, pp.265~271 (2010)
  41. 윤영훈, "Peroral Endoscopic Myotomy for Treating Achalasia and Esophageal Motility Disorders", Journal of Neurogastroenterology and Motility (JNM), 22(1), pp.14~24 (2016), 대한소화기 기능성질환∙운동학회[DOI]
  42. Stavropoulos SN, "Achalasia", Gastrointest Endosc Clin N Am, 23, pp.53~75 (2013)
  43. Maselli R, "Microvasculature of the esophagus and gastroesophageal junction : lesson learned from submucosal endoscopy", World J Gastrointest Endosc, 8, pp.690~696 (2016)
  44. Grimes KL, "Double-scope per oral endoscopic myotomy(POEM) : a prospective randomized controlled trial", Surg Endosc, 30, pp.1344~1351 (2016)
  45. Crespin OM, "Safety and efficacy of POEM for treatment of achalasia : a systematic review of the literature", Surg Endosc, 31, pp.2187~2201 (2017)
  46. Ju Yup Lee, "Adverse Events Associated With Peroral Endoscopic Myotomy Affecting Extended Hospital Stay: A Multi-center Retrospective Study in South Korea", Journal of Neurogastroenterology and Motility (JNM), 28(2), pp.247~254 (2022), 대한소화기 기능성질환∙운동학회[DOI]
  47. Ren Z, "Perioperative management and treatment for complications during and after peroral endoscopic myotomy(POEM)for esophageal achalasia(EA)(data from 119 cases)", Surg Endosc, 26, pp.3267~3272 (2012)
  48. Hungness ES, "Per-oral endoscopic myotomy(POEM)after the learning curve : durable long-term results with a low complication rate", Ann Surg, 264, pp.508~517 (2016)
  49. Repici A, "GERD after per-oral endoscopic myotomy as compared with Heller's myotomy with fundoplication : a systematic review with meta-analysis", Gastrointest Endosc, 87, pp.934~943 (2018)
  50. Bapaye A, "Single-session endoscopic fundoplication after peroral endoscopic myotomy(POEM+F)for prevention of post gastroesophageal reflux : 1-year follow-up study", Endoscopy, 53, pp.1114~1121 (2021)
  51. Inoue H, "Peroral endoscopic myotomy and fundoplication : a novel NOTES procedure", Endoscopy, 51, pp.161~164 (2019)
  52. Li QL, "Outcomes of per-oral endoscopic myotomy for treatment of esophageal achalasia with a median follow-up of 49 months", Gastrointest Endosc, 87, pp.1405~1412 (2018)
  53. Brewer Gutierrez OI, "Long-term outcomes of per-oral endoscopic myotomy in achalasia patients with a minimum follow-up of 4 years : a multicenter study", Endosc Int Open, 8, pp.E650~ (2020)
  54. Nabi Z, "Impact of prior treatment on long-term outcome of peroral endoscopic myotomy in pediatric achalasia", J Pediatr Surg, 55, pp.1552~1555 (2020)
  55. Xu S, "Outcomes of peroral endoscopic myotomy in challenging achalasia patients : a long-term follow-up study", Surg Endosc, 35, pp.3732~3743 (2021)
  56. Podboy AJ, "Long-term outcomes of per-oral endoscopic myotomy compared to laparoscopic Heller myotomy for achalasia : a single-center experience", Surg Endosc, 35, pp.792~801 (2021)
  57. Shiwaku H, "Multicenter collaborative retrospective evaluation of peroral endoscopic myotomy for esophageal achalasia : analysis of data from more than 1300 patients at eight facilities in Japan", Surg Endosc, 34, pp.464~468 (2020)
  58. Ponds FA, "Effect of peroral endoscopic myotomy vs pneumatic dilation on symptom severity and treatment outcomes among treatment-naïve patients with achalasia : a randomized clinical trial", JAMA, 322, pp.134~144 (2019)
  59. Schlottmann F, "Laparoscopic Heller myotomy versus peroral endoscopic myotomy(POEM)for achalasia : a systematic review and meta-analysis", Ann Surg, 267, pp.451~460 (2018)
  60. Kumbhari V, "Peroral endoscopic myotomy(POEM)vs laparoscopic Heller myotomy(LHM)for the treatment of Type III achalasia in 75 patients : a multicenter comparative study", Endosc Int Open, 3, pp.E195~ (2015)
  61. Eckardt AJ, "Editorial : cancer surveillance in achalasia. Better late than never?", Am J Gastroenterol, 105, pp.2150~2152 (2010)
  62. Leeuwenburgh I, "Long-term esophageal cancer risk in patients with primary achalasia : a prospective study", Am J Gastroenterol, 105, pp.2144~2149 (2010)
  63. Sandler RS, "The risk of esophageal cancer in patients with achalasia. A population-based study", JAMA, 274, pp.1359~1362 (1995)
  64. Zendehdel K, "Risk of esophageal adenocarcinoma in achalasia patients, a retrospective cohort study in Sweden", Am J Gastroenterol, 106, pp.57~61 (2011)
  65. Leeuwenburgh I, "Barrett's esophagus and esophageal adenocarcinoma are common after treatment for achalasia", Dig Dis Sci, 58, pp.244~252 (2013)
  66. Ide E, "Endoscopic detection of early esophageal squamous cell carcinoma in patients with achalasia : narrow-band imaging versus Lugol's staining", J Oncol, 2013, pp.736756~ (2013)
  67. Ponds FA, "Screening for dysplasia with Lugol chromoendoscopy in longstanding idiopathic achalasia", Am J Gastroenterol, 113, pp.855~862 (2018)

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