HIV 감염인에서 발생한 골다공증성 골절: 증례보고 및 문헌고찰
HIV-Infected Patients with Osteoporotic Fractures: A Case Report and Review of the Literature
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항레트로바이러스 치료제의 발달로 HIV 감염인의 수명이획기적으로 연장되면서 비에이즈(non-acquired immune deficiencysyndrome) 관련 질환인 심혈관 질환, 암, 골다공증성골절 등의 합병증도 증가했다. 특히 HIV 감염인은 비감염인에 비해 골다공증 유병률이 약 3배 정도 높고 골절은 약 2배정도 높다. 고령의 HIV 감염인이 많아지면서 조기에 골다공증을 진단하고 치료하기 위한 BMD 검사가 중요하게 되었다. 본 연구에서는 국내 HIV 감염인에서 발생한 골다공증성골절 6예를 경험했기에 이를 문헌고찰과 함께 보고하는 바이다.
Abstract
The average life expectancy of human immunodeficiency virus (HIV)-infected patients has improved dramatically following theadvent of highly active anti-retroviral therapy. However, this increased life expectancy has led to a greater incidence of non-acquiredimmune deficiency syndrome related diseases, including cardiovascular diseases and other malignancies. Increased bonefragility is also a significant concern, with the incidence of osteoporosis and osteoporotic fractures 3- and 2-times more likely, respectively,among HIV-infected patients. Bone mineral density screenings for osteoporosis will therefore become more important asthe HIV-infected population ages. Here, we describe six cases of osteoporotic fractures in HIV-infected patients in Korea.
참고문헌 (10)
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