뇌하수체 침범 뇌수막종 환자에서 고나트륨혈증에 의한 횡문근 융해증
Hypernatremia-Induced Rhabdomyolysis in a Patient with Meningioma Involving the Pituitary Gland
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초록
횡문근 융해증의 원인에 고나트륨혈증이 속해 있지만 보고된 증례는 드물다. 본 저자들은 뇌하수체를 침범하는 거대뇌수막종 환자에서 중추성 요붕증으로 인한 것으로 추정되는 고나트륨혈증에 의해 횡문근 융해증이 발생한 환자를 경험했다. 데스모프레신 투여 후에 고나트륨혈증 및 횡문근 융해증이 함께 호전되는 임상경과를 보인 증례를 경험했기에문헌고찰과 함께 보고하는 바이다.
Abstract
with meningioma involving the pituitary gland. A 61-year-old male was admitted for decreased mentality and poor oral intake. Hehad undergone an operation for meningioma 10 years prior. At admission, he appeared lethargic and severely dehydrated with an initialsodium level of 178 mEq/L. Hypernatremia remained persistent despite massive hydration and the serum creatine phosphokinaselevel was 18,047 U/L after 3 days. Bone scintigraphy also showed findings consistent with rhabdomyolysis. Brain magneticresonance imaging revealed extensive masses involving the pituitary gland and an intranasal biopsy confirmed meningioma. Polyuria, and low anti-diuretic hormone levels supported the diagnosis of central diabetes insipidus-induced hypernatremia. Desmopressin was administered intranasally and the patient’s serum sodium and muscle enzyme levels were normalized.
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