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Colonic MALT Lymphoma Diagnosed 6 Months after Complete Remission of Gastric MALT Lymphoma

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초록

Mucosa-associated lymphoid tissue (MALT) lymphomas are a distinct group of malignant extranodal lymphoepithelial lesions. They were first described by Isaacson and Wright as lymphomas arising from MALT [1]. They can occur in almost any organ exposed to a persistent stimulus, such as chronic infection or an autoimmune condition [2]. The most common site is the stomach, and other gastrointestinal sites include the large and small bowel. Colonic MALT lymphoma is rare; here we report an extremely rare case of a primary colonic MALT lymphoma presenting 6 months after completion of radiation therapy for gastric MALT lymphoma.

Abstract

Most mucosa-associated lymphoid tissue (MALT) lymphomas are found in the gastrointestinal tract. The most common site is the stomach, whereas colon MALT lymphomas are rare. There are a few reports of simultaneously diagnosed stomach and colon MALT lymphomas. However, diagnosis of primary colonic MALT lymphoma after complete remission of gastric MALT lymphoma is extremely rare. Although the treatment protocol for gastric MALT lymphoma is well established, there is no consensus protocol for colonic MALT lymphoma owing to its rarity. Herein, we report a case of colonic MALT lymphoma incidentally diagnosed 6 months after completion of radiation therapy for gastric MALT lymphoma and treated via polypectomy, with no recurrence for 3 years.

참고문헌 (9)

  1. Isaacson PG, "Classifying primary gut lymphomas", Lancet, 2, pp.1148~1149 (1988)
  2. Suarez F, "Infection-associated lymphomas derived from marginal zone B cells : a model of antigen-driven lymphoproliferation", Blood, 107, pp.3034~3044 (2006)
  3. Zinzani P, "Nongastrointestinal mucosa-associated lymphoid tissue(MALT)lymphomas : clinical and therapeutic features of 24 localized patients", Ann Oncol, 8, pp.883~886 (1997)
  4. 정지현, "Synchronous Primary Low-grade Mucosa-associated Lymphoid Tissue Lymphoma of Colon and Stomach", Intestinal research, 11(3), pp.204~207 (2013), 대한장연구학회
  5. Matsumoto T, "Primary low-grade, B-cell, mucosa-associated lymphoid tissue lymphoma of the colorectum : clinical and colonoscopic features in six cases", Gastrointest Endosc, 48, pp.501~508 (1998)
  6. Neubauer A, "Cure of Helicobacter pylori infection and duration of remission of low-grade gastric mucosa-associated lymphoid tissue lymphoma", J Natl Cancer Inst, 89, pp.1350~1355 (1997)
  7. Lee SK, "Low grade gastric mucosa associated lymphoid tissue lymphoma : treatment strategies based on 10 year follow-up", World J Gastroenterol, 10, pp.223~226 (2004)
  8. Raderer M, "Regression of colonic low grade B cell lymphoma of the mucosa associated lymphoid tissue type after eradication of Helicobacter pylori", Gut, 46, pp.133~135 (2000)
  9. Matsumoto T, "Regression of mucosa-associated lymphoid-tissue lymphoma of rectum after eradication of Helicobacter pylori", Lancet, 350, pp.115~116 (1997)

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