결핵 환자에서 고혈압으로 발현된 타카야수동맥염
Takayasu's Arteritis Presenting with Hypertension in Pulmonary Tuberculosis
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초록
타카야수동맥염의 발병 원인은 확실히 밝혀져 있지 않지만, 염증성 질환의 하나로 판단되며 이에 결핵 항원에 대한자가면역 반응이 타카야수동맥염의 병인으로 제기되고 있다. 저자들은 타카야수동맥염이 좌측 신동맥을 침범하여 이차성 고혈압이 발생하고 활동성 폐결핵이 동반된 환자를 치료하여 보고하는 바이다.
Abstract
Takayasu's arteritis (TA) is an inflammatory disease involving large arteries and their branches. The etiology of TA is unknown, but infectious agents and genetic factors play a significant role in its pathogenesis. A relationship between TA and Mycobacterium tuberculosis infection has been suggested, since both diseases have similar chronic inflammatory lesions and the presence of occasional granulomas in arterial walls. Patients with TA have an increased immune response to Mycobacterium tuberculosis antigens, suggesting a role for this organism in the immunopathogenesis of the disease. Herein, we present a case of TA with active pulmonary tuberculosis in a Korean patient. A 21-year-old male presented with hypertension and active pulmonary tuberculosis. TA invading the renal artery was diagnosed while evaluating hypertension. The patient was treated with prednisolone, methotrexate, anti-hypertensive medications, and anti-tuberculosis medications.
참고문헌 (10)
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