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논문KCI 등재

전신성 경화증과 동반된 폐암 및 갑상선암 1예

Systemic Sclerosis Associated with Non-small Cell Lung Cancer and Papillary Thyroid Cancer: Case Report and Literature Review

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주제분류내과학

초록

전신성 경화증을 앓고 있는 환자에서 암 발생률은 3-11% 에 이른다고 보고되어 있다. 특히 전신성 경화증 환자에서 폐암과 유방암은 유의하게 증가한다고 알려져 있지만 아직 전신성 경화증과 암 발생률의 연관성에 대해서는 논란이 있다. 우리는 전신성 경화증을 앓고 있는 52세 여자 환자에서 비소세포성 폐암, 유두갑상생암종의 중복암을 관찰하였고 매우드문 증례로 판단되어 문헌고찰과 함께 보고하는 바이다.

Abstract

We report the case of a 52-year-old patient with rheumatic vascular disease (systemic sclerosis), non-small cell lung cancer, and papillary thyroid cancer. Malignant tumors have been described in 3-11% of systemic sclerosis cases. Several studies have demonstrated an increased frequency of cancer, especially lung and breast cancer, in patients with systemic sclerosis, but the association of systemic sclerosis with malignancy is controversial. To our knowledge, however, no case of both lung and thyroid cancer associated with systemic sclerosis has been reported. We present a rare case of double primary cancer in systemic sclerosis, with a literature review.

참고문헌 (10)

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  3. Antonelli A, "Increased risk of papillary thyroid cancer in systemic sclerosis associated with autoimmune thyroiditis", Rheumatology (Oxford), 55, pp.480~484 (2016)
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  6. Kang KY, "Incidence of cancer among patients with systemic sclerosis in Korea: results from a single centre", Scand J Rheumatol, 38, pp.299~303 (2009)
  7. 이상엽, "전신성 경피증에 동반된 갑상선 기능저하증과 부갑상선 기능저하증 1예", 대한내과학회지, 63(6), pp.11~700 (2002), 대한내과학회
  8. 이윤정, "그레이브스병과 동반된 전신성 경피증 1예", Endocrinology and Metabolism, 22(3), pp.220~224 (2007), 대한내분비학회
  9. Zeineddine N, "systemic sclerosis and malignancy: a review of current data", J Clin Med Res, 8, pp.625~632 (2016)
  10. Marek M, "Scleroderma of geriatric age and scleroderma-like paraneoplastic syndrome - description of two cases", Reumatologia, 54, pp.91~94 (2016)

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