항생제 약물알레르기의 진단과 관리
Diagnosis and Management of Antibiotic Allergies
2
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Drug allergies encompass a spectrum of immune-mediated hypersensitivity reactions with various mechanisms and clinical presentations. β-lactam drugs are common causes of drug allergies. A detailed clinical history as well as skin and drug provocation tests, are essential to diagnose drug allergies. The key to successful treatment is avoidance or discontinuation of the offending drug, and replacing it with a safe alternative. Cross-reactivities among β-lactam antibiotics should be considered when choosing alternative medications. Proper management of β-lactam allergies is important at the individual and population levels, to reduce the likelihood of drug allergies and prevent antibiotic-related adverse outcomes.
Abstract
Drug allergies encompass a spectrum of immune-mediated hypersensitivity reactions with various mechanisms and clinical presentations. β-lactam drugs are common causes of drug allergies. A detailed clinical history as well as skin and drug provocation tests, are essential to diagnose drug allergies. The key to successful treatment is avoidance or discontinuation of the offending drug, and replacing it with a safe alternative. Cross-reactivities among β-lactam antibiotics should be considered when choosing alternative medications. Proper management of β-lactam allergies is important at the individual and population levels, to reduce the likelihood of drug allergies and prevent antibiotic-related adverse outcomes.
참고문헌 (24)
- International drug monitoring : the role of national centres, "Report of a WHO meeting", World Health Organ Tech Rep Ser, 498, pp.1~25 (1972)
- Solensky R, "Middleton's allergy: principles and practice", pp.1261~1282 (2020), Elsevier
- Romano A, "Towards a more precise diagnosis of hypersensitivity to beta-lactams-an EAACI position paper", Allergy, 75, pp.1300~1315 (2020)
- Mayorga C, "Recent developments and highlights in drug hypersensitivity", Allergy, 74, pp.2368~2381 (2019)
- 양민석, "약물알레르기 검사의 시행과 해석: 전문가 의견서", Allergy Asthma & Respiratory Disease, 5(5), pp.239~247 (2017), 대한 소아알레르기 호흡기학회[DOI]
- Barbaud A, "A multicentre study to determine the value and safety of drug patch tests for the three main classes of severe cutaneous adverse drug reactions", Br J Dermatol, 168, pp.555~562 (2013)
- Phillips EJ, "Controversies in drug allergy : testing for delayed reactions", J Allergy Clin Immunol, 143, pp.66~73 (2019)
- Blanca M, "Update on the evaluation of hypersensitivity reactions to betalactams", Allergy, 64, pp.183~193 (2009)
- Mayorga C, "In vitro tests for drug hypersensitivity reactions : an ENDA", EAACI Drug Allergy Interest Group position paper, 2016, pp.71, 1103~1134
- Jae-Woo Jung, "Genetic markers of severe cutaneous adverse reactions", The Korean Journal of Internal Medicine, 33(5), pp.867~875 (2018), 대한내과학회[DOI]
- Broyles AD, "Practical guidance for the evaluation and management of drug hypersensitivity:specific drugs", J Allergy Clin Immunol Pract, 8, pp.S16~S116 (2020)
- Staicu ML, "Penicillin allergy delabeling : a multidisciplinary opportunity", J Allergy Clin Immunol Pract, 8, pp.2858~2868 (2020)
- Shenoy ES, "Evaluation and management of penicillin allergy : a review", JAMA, 321, pp.188~199 (2019)
- Vyles D, "Children with reported penicillin allergy : public health impact and safety of delabeling", Ann Allergy Asthma Immunol, 124, pp.558~565 (2020)
- Barlam TF, "Executive summary : implementing an antibiotic stewardship program : guidelines by the Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America", Clin Infect Dis, 62, pp.1197~1202 (2016)
- 김민혜, "Diagnosis and Management of Immediate Hypersensitivity Reactions to Cephalosporins", Allergy, Asthma & Immunology Research, 6(6), pp.485~495 (2014), 대한천식알레르기학회
- Iammatteo M, "Safety and outcomes of test doses for the evaluation of adverse drug reactions : a 5-year retrospective review", J Allergy Clin Immunol Pract, 2, pp.768~774 (2014)
- Blumenthal KG, "Impact of a clinical guideline for prescribing antibiotics to inpatients reporting penicillin or cephalosporin allergy", Ann Allergy Asthma Immunol, 115, pp.294~300 (2015)
- Chopra N, "Vancomycin anaphylaxis and successful desensitization in a patient with end stage renal disease on hemodialysis by maintaining steady antibiotic levels", Ann Allergy Asthma Immunol, 84, pp.633~635 (2000)
- 이상희, "탈감작요법으로 치료한 반코마이신 과민성 1예", Allergy Asthma & Respiratory Disease, 1(2), pp.168~171 (2013), 대한 소아알레르기 호흡기학회
- 윤도란, "Trimethoprim-sulfamethoxazole에 대해 지연성 과민반응을 보인 환자에서 성공적인 급속 탈감작 치료 사례 1예", Allergy Asthma & Respiratory Disease, 3(2), pp.155~158 (2015), 대한 소아알레르기 호흡기학회
- Ban GY, "Efficacy and tolerability of desensitization in the treatment of delayed drug hypersensitivities to anti-tuberculosis medications", Respir Med, 147, pp.44~50 (2019)
- 이혜림, "소아에서 성공한 isoniazid와 rifampin에 대한 신속탈감작요법 1예", Allergy Asthma & Respiratory Disease, 4(3), pp.212~216 (2016), 대한 소아알레르기 호흡기학회[DOI]
- Castells M, "Rapid desensitization for hypersensitivity reactions to medications", Immunol Allergy Clin North Am, 29, pp.585~606 (2009)