호기산화질소 검사의 시행과 해석
Measurement and Interpretation of Fractional Exhaled Nitric Oxide
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Nitric oxide is produced by the human lungs and increases in response to type 2 inflammation. The level of fractional exhaled nitric oxide (FeNO) may reflect type 2 inflammation in the airways, which is related to eosinophilic inflammation and treatment responsiveness to corticosteroids. The FeNO test is a non-invasive, simple, and safe point-of-care test to evaluate airway inflammation. It has been standardized for clinical use and has been widely utilized in daily medical practice. However, various intrinsic and extrinsic factors can affect FeNO levels, and understanding and controlling such factors will improve the utility of this measure. The FeNO test can be used to confirm an asthma diagnosis, predict treatment responses to corticosteroids, and guide inhaled corticosteroid therapy for asthma treatment.
Abstract
Nitric oxide is produced by the human lungs and increases in response to type 2 inflammation. The level of fractional exhaled nitric oxide (FeNO) may reflect type 2 inflammation in the airways, which is related to eosinophilic inflammation and treatment responsiveness to corticosteroids. The FeNO test is a non-invasive, simple, and safe point-of-care test to evaluate airway inflammation. It has been standardized for clinical use and has been widely utilized in daily medical practice. However, various intrinsic and extrinsic factors can affect FeNO levels, and understanding and controlling such factors will improve the utility of this measure. The FeNO test can be used to confirm an asthma diagnosis, predict treatment responses to corticosteroids, and guide inhaled corticosteroid therapy for asthma treatment.
참고문헌 (20)
- Petsky HL, "Tailoring asthma treatment on eosinophilic markers (exhaled nitric oxide or sputum eosinophils): a systematic review and meta-analysis", Thorax, 73, pp.1110~1119 (2018)
- Rupani H, "Using fractional exhaled nitric oxide measurement in clinical asthma management", Chest, 161, pp.906~917 (2022)
- American Thoracic Society, "ATS", ERS recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide, 2005, 2005, pp.171, 912~930
- 권재우, "호기산화질소 측정 검사 시행과 해석: 전문가 의견서", Allergy Asthma & Respiratory Disease, 5(4), pp.185~192 (2017), 대한 소아알레르기 호흡기학회[DOI]
- 윤세효, "Fractional Exhaled Nitric Oxide: Comparison Between Portable Devices and Correlation With Sputum Eosinophils", Allergy, Asthma & Immunology Research, 7(4), pp.404~408 (2015), 대한천식알레르기학회
- Korevaar DA, "Diagnostic accuracy of minimally invasive markers for detection of airway eosinophilia in asthma : a systematic review and meta-analysis", Lancet Respir Med, 3, pp.290~300 (2015)
- 송우정, "Clinical Application of Exhaled Nitric Oxide Measurements in a Korean Population", Allergy, Asthma & Immunology Research, 7(1), pp.3~13 (2015), 대한천식알레르기학회
- Dweik RA, "An official ATS clinical practice guideline: interpretation of exhaled nitric oxide levels (FENO) for clinical applications", Am J Respir Crit Care Med, 184, pp.602~615 (2011)
- 오상유, "천식 의심 환자에서 기관지 확장제 반응 및 만니톨 기도과민성과 호기산화질소의 연관성", 대한내과학회지, 92(5), pp.458~466 (2017), 대한내과학회[DOI]
- "Global strategy for asthma management and prevention" (2021)[URL]
- Song WJ, "Diagnostic accuracy of fractional exhaled nitric oxide measurement in predicting cough-variant asthma and eosinophilic bronchitis in adults with chronic cough : a systematic review and meta-analysis", J Allergy Clin Immunol, 140, pp.701~709 (2017)
- Song WJ, "Could fractional exhaled nitric oxide test be useful in predicting inhaled corticosteroid responsiveness in chronic cough? A systematic review", J Allergy Clin Immunol Pract, 5, pp.135~143.e1 (2017)
- Oh MJ, "Exhaled nitric oxide measurement is useful for the exclusion of nonasthmatic eosinophilic bronchitis in patients with chronic cough", Chest, 134, pp.990~995 (2008)
- "Guidelines for management of chronic cough" (2018)[URL]
- Karrasch S, "Accuracy of FENO for diagnosing asthma : a systematic review", Thorax, 72, pp.109~116 (2017)
- 김상헌, "호기산화질소 측정을 이용한 천식 치료", 대한내과학회지, 92(5), pp.453~457 (2017), 대한내과학회[DOI]
- Khatri SB, "Use of fractional exhaled nitric oxide to guide the treatment of asthma : an Official American Thoracic Society clinical practice guideline", Am J Respir Crit Care Med, 204, pp.e97~e109 (2021)
- Zietkowski Z, "The influence of inhaled corticosteroids on exhaled nitric oxide in stable chronic obstructive pulmonary disease", Respir Med, 99, pp.816~824 (2005)
- Lee JE, "Fraction of exhaled nitric oxide in patients with acute eosinophilic pneumonia", Chest, 141, pp.1267~1272 (2012)
- Park JY, "Significance of fractional exhaled nitric oxide in chronic eosinophilic pneumonia : a retrospective cohort study", BMC Pulm Med, 14, pp.81~ (2014)