Role of fully covered metal stents in the management of chronic pancreatitis
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Chronic pancreatitis (CP), a progressive inflammatory disease that results in irreversible pancreatic damage, is often complicated byductal strictures and debilitating pain. Fully covered self-expandable metal stents (FCSEMS) have emerged as significant innovations inthe endoscopic management of refractory pancreatic duct strictures. This review synthesizes recent evidence highlighting the benefitsand limitations of FCSEMS, such as superior patency, reduced need for reinterventions, and effective symptom relief compared to traditionalplastic stents, alongside risks, such as stent migration and de novo strictures. A comparison with plastic stents and an algorithmfor pancreatic duct stricture management are provided. Regional variations in clinical guidelines from the United States, Europe, Japan,and Korea reflect diverse approaches to integrating FCSEMS into practice. Emerging innovations in stent technology are promising forimproving CP management outcomes.
Abstract
Chronic pancreatitis (CP), a progressive inflammatory disease that results in irreversible pancreatic damage, is often complicated byductal strictures and debilitating pain. Fully covered self-expandable metal stents (FCSEMS) have emerged as significant innovations inthe endoscopic management of refractory pancreatic duct strictures. This review synthesizes recent evidence highlighting the benefitsand limitations of FCSEMS, such as superior patency, reduced need for reinterventions, and effective symptom relief compared to traditionalplastic stents, alongside risks, such as stent migration and de novo strictures. A comparison with plastic stents and an algorithmfor pancreatic duct stricture management are provided. Regional variations in clinical guidelines from the United States, Europe, Japan,and Korea reflect diverse approaches to integrating FCSEMS into practice. Emerging innovations in stent technology are promising forimproving CP management outcomes.