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A Case of Pulmonary Cryptococcosis with Non-Small Cell Lung Cancer in Idiopathic CD4+ T-Lymphocytopenia

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Abstract

Cryptococcus neoformans commonly causes opportunistic infections in immunocompromised patients, especially in patients with AIDS. CD4+ T-lymphocytopenia in AIDS indicates an increased risk of opportunistic infection and a decline in immunological function. Idiopathic CD4 T-lymphocytopenia (ICL) is characterized by depletions in the CD4+ T-cell subsets, without evidence of HIV infection. Immunodeficiency can exist in the absence of laboratory evidence of HIV infection, and T-cell subsets should be evaluated in patients who present with unusual opportunistic infections. We report a case of pulmonary cryptococcosis and lung cancer in a patient with persistently low CD4+ cell counts, without evidence of HIV infection.

참고문헌 (10)

  1. "Centers for Disease Control and Prevention Unexplained CD4+ T lymphocyte depletion in persons without evident HIV infection", pp.541~5
  2. "Unexplained opportunistic infections and CD4+ T lymphocytopenia without HIV infection", pp.373~9
  3. "Apoptotic depletion of CD4+ T cells in idiopathic CD4+ T lymphocytopenia", 97, pp.672~80 (1996)
  4. "Apoptotic cell death of primed CD45RO+ T lymphocytes in Epstein-Barr virus-induced infectious mononucleosis", pp.452~8
  5. "CD4+ T-lymphocytopenia without HIV infection", pp.429~31
  6. "Invasive cryptococcosis in a family with epidermodysplasia verruciformis and idiopathic CD4 cell depletion", 25, pp.1252~3 (1997)
  7. "Idiopathic CD4+ T-lymphocytopenia in a child with disseminated cryptococcosis", 18, pp.45~8 (1998)
  8. "Infections with Cryptococcus neoformans in the acquired immunodeficiency syndrome", pp.794~9
  9. "1999 USPHS", IDSA guideline for the prevention of opportunistic infections in persons infected with human immunodeficiency virus, 1999, pp.48, 1~65
  10. "Cryptococcosis in human immunodeficiency virus-negative patients in the era of effective azole therapy", 33, pp.690~9 (2001)

관련 논문AI추천

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