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The Effect of Pretreatment with Thiopental on Reducing Pain Induced by Rocuronium Injection

김순열|최재찬|유영수|이영복|임현교|박종택
연세대학교의과대학 (Yonsei University College of Medicine)|2005.12|Yonsei Medical Journal|제46권 제6호|pp. 765-768

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참고문헌

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초록

Abstract

We examined whether pretreatment with a small dose of thiopental was effective in reducing pain induced by the intravenous injection of rocuronium. Withdrawal movement was used to assess pain reduction. Ninety patients were randomly assigned to one of two groups: patients in the control group were pretreated with 2mL saline, and those in the thiopental group were pretreated with 2mL (50mg) thiopental. Thiopental 5mg/kg was injected intravenously. After a loss of consciousness, the upper arm was compressed with a rubber tourniquet, and the pretreatment drugs were administered. Thirty seconds later the tourniquet was removed and 0.6mg/kg rocuronium was administered. Withdrawal movement was assessed using a four-grade scale: no movement, movement limited to the wrist, to the elbow or to the shoulder. The frequency of withdrawal movement in the group pretreated with thiopental was lower than in the control group (34 vs. 13, p <0.05). We concluded that pretreatment with 2mL (50mg) thiopental is effective in reducing pain caused by the intravenous injection of rocuronium.

참고문헌 (17)

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