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Further Increase of Vancomycin-Resistant Enterococcus faecium, Amikacin- and Fluoroquinolone-Resistant Klebsiella pneumoniae, and Imipenem-Resistant Acinetobacter spp. in Korea

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초록

Abstract

Monitoring temporal trends of antimicrobial resistance can provide useful information for the empirical selection of antimicrobial agents to treat infected patients and for the control of nosocomial infections. In this study, we analyzed antimicrobial resistance of clinically relevant bacteria in 2003 at Korean hospitals and at a commercial laboratory. The following organism-antimicrobial agent resistance combinations were very prevalent: oxacillin-resistant Staphylococcus aureus (68%), expanded-spectrum cephalosporin-resistant Klebsiella pneumoniae (25%), and fluoroquinolone-resistant Escherichia coli (33%), Acinetobacter spp. (58%), and Pseudomonas aeruginosa (40%). Moreover, gradual increases in vancomycin- resistant Enterococcus faecium (20%), cefoxitin-resistant E. coli (10%) and K. pneumoniae (23%), and imipenem-resistant P. aeruginosa (20%) and Acinetobacter spp. (13%) were also observed. The resistance rates of Acinetobacter spp. to most antimicrobial agents at hospitals and at the commercial laboratory were similar. Among the Acinetobacter spp. isolated at a tertiary-care hospital, 46.2% were multidrug-resistant to 9-12 of 13 antimicrobial agents, and 18.3% were panresistant. The exclusion of duplicate isolates at a tertiary-care hospital significantly lowered the proportion of oxacillin-resistant S. aureus, vancomycin-resistant E. faecium, and fluoroquinolone-resistant E. coli.

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관련 논문AI추천

Further Increases in Carbapenem-, Amikacin-, and Fluoroquinolone-Resistant Isolates of Acinetobacter spp. and P. aeruginosa in Korea: KONSAR Study 2009강정옥, 김미나, 김재석, 박연준, 신종희, 용동은, 이경원, 장숙진, 정석훈, 홍혜림, The KONSAR Group, Yunsop Chong연세대학교의과대학 · Yonsei Medical Journal2011 · 제52권 제5호Increase of Ceftazidime- and Fluoroquinolone-Resistant Klebsiella pneumoniae and Imipenem-Resistant Acinetobacter spp. in Korea: Analysis of KONSAR Study Data from 2005 and 2007고은미, 김선주, 김진주, 노경호, 용동은, 이경원, 이미애, 이종욱, 이채훈, 정윤섭연세대학교의과대학 · Yonsei Medical Journal2010 · 제51권 제6호Increasing Resistance to Extended-Spectrum Cephalosporins, Fluoroquinolone, and Carbapenem in Gram-Negative Bacilli and the Emergence of Carbapenem Non-Susceptibility in Klebsiella pneumoniae: Analysis of Korean Antimicrobial Resistance Monitoring System (KARMS) Data From 2013 to 2015김도균, 안지영, 용동은, 이경원, 이채훈, 이혁민, 장숙진, 정석훈대한진단검사의학회 · Annals of Laboratory Medicine2017 · 제37권 제3호Increase in the Prevalence of Carbapenem-Resistant Acinetobacter Isolates and Ampicillin-Resistant Non- Typhoidal Salmonella Species김용근, 신희봉, 용동은, 이경원, 이위교, 정석훈, 정윤섭, 조지현, 최태열, 하경임대한감염학회 · Infection and Chemotherapy2014 · 제46권 제2호High Prevalence of Ceftazidime-Resistant Klebsiella pneumoniae and Increase of Imipenem-Resistant어영, 김희준, 용동은, 이경원, 이위규, 임장현, 정윤섭, 조지현연세대학교의과대학 · Yonsei Medical Journal2006 · 제47권 제5호Are Community-Based Hospitals Safe from Carbapenem-Resistant Enterobacteriaceae in Korea?이창섭대한감염학회 · Infection and Chemotherapy2016 · 제48권 제3호

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