The Effect of Fish Consumption on Blood Mercury Levels of Pregnant Women
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In the present study, we examined the relationship between average fish consumption, as well as the type of fish consumed and levels of mercury in the blood of pregnant women. We also performed follow-up studies to determine if blood mercury levels were decreased after counseling and prenatal education. To examine these potential relationships, pregnant women were divided into two groups: a study group was educated to restrict fish intake, whereas a control group did not receive any prenatal education regarding fish consumption. We measured blood mercury level and performed follow-up studies during the third trimester to examine any differences between the two groups. Out of the 63 pregnant women who participated in our study, we performed follow- up studies with 19 pregnant women from the study group and 12 pregnant women from control group. The average initial blood mercury level of both groups was 2.94 μg/L, with a range of 0.14 to 10.75μg/L. Blood mercury level in the group who ate fish more than four times per month was significantly higher than that of the group who did not consume fish (p=0.02). In follow-up studies, blood mercury levels were decreased in the study group but slightly increased in the control group (p=0.014). The maternal blood mercury level in late pregnancy was positively correlated with mercury levels of cord blood (r=0.58, p=0.047), which was almost twice the level found in maternal blood. Pregnant women who consume a large amount of fish may have high blood mercury levels. Further, cord blood mercury levels were much higher than that of maternal blood. Because the level of fish intake appears to influence blood mercury level, preconceptual education might be necessary in order decrease fish consumption.
Abstract
In the present study, we examined the relationship between average fish consumption, as well as the type of fish consumed and levels of mercury in the blood of pregnant women. We also performed follow-up studies to determine if blood mercury levels were decreased after counseling and prenatal education. To examine these potential relationships, pregnant women were divided into two groups: a study group was educated to restrict fish intake, whereas a control group did not receive any prenatal education regarding fish consumption. We measured blood mercury level and performed follow-up studies during the third trimester to examine any differences between the two groups. Out of the 63 pregnant women who participated in our study, we performed follow- up studies with 19 pregnant women from the study group and 12 pregnant women from control group. The average initial blood mercury level of both groups was 2.94 μg/L, with a range of 0.14 to 10.75μg/L. Blood mercury level in the group who ate fish more than four times per month was significantly higher than that of the group who did not consume fish (p=0.02). In follow-up studies, blood mercury levels were decreased in the study group but slightly increased in the control group (p=0.014). The maternal blood mercury level in late pregnancy was positively correlated with mercury levels of cord blood (r=0.58, p=0.047), which was almost twice the level found in maternal blood. Pregnant women who consume a large amount of fish may have high blood mercury levels. Further, cord blood mercury levels were much higher than that of maternal blood. Because the level of fish intake appears to influence blood mercury level, preconceptual education might be necessary in order decrease fish consumption.
참고문헌 (23)
- "VIII Heavy Metal", pp.484~486 (2003), Publishing Company Medical Culture
- "Intra-uterine methylmercury poisoning in Iraq", pp.587~95
- "Mercury Study Report to Congress, Volume I: Executive Summary" (1997), Environmental Protection Agency
- "Prenatal methylmercury exposure from ocean fish consumption in the Seychelles child development study", 361, pp.1686~1692 (2003)
- "Neurotoxic risk caused by stable and variable exposure to methylmercury from seafood", 3, pp.18~23 (2003)
- "Background levels of total mercury concentrations in blood and urine", pp.66~9
- "Placental transfer of heavy metals in normal pregnant Japanese women", pp.11~7
- "Blood mercury levels in US children and women of childbearing age 1999-2000", 289, pp.1667~1674 (2003)
- "Cognitive deficit in 7-year-old children with prenatal exposure to methylmercury", 19, pp.417~428 (1997)
- "Effects of prenatal and postnatal methylmercury exposure form fish consumption on neurodevelopment", 280, pp.701~707 (1998)
- "Longitudinal study of methylmercury and inorganic mercury in blood and urine of pregnant and lactating women, as well as in umbilical cord blood", 84, pp.186~194 (2000)
- "2004 EPA and FDA Advice For: Women who might become pregnant, women who are pregnant, nursing mothers, young children"
- "Consumer advisory: An important message for pregnant women and women of childbearing age who may become pregnant about the risks of mercury in fish" (2001), FDA
- "Food safety facts on mercury and fish consumption"
- "Agency updates advice to pregnant and breastfeeding women on eating certain fish"
- "Methylmercury (Environment Health Criteria 101)" (1990), World Health Organization
- "Heavy metal intoxification", pp.702~703 (2004), Nelson Textbook of Pediatrics
- "Low consumption of seafood in early pregnancy as a risk factor for preterm delivery: prospective cohort study", 324, pp.447~ (2002)
- "Frequency of seafood intake in pregnancy as a determinant of birth weight: evidence for a dose dependent relationship", pp.436~40
- "Fish and omega-3 fatty acid intake and risk of coronary heart disease in women", 287, pp.1815~1821 (2002)
- "Mercury, fish oils, and the risk of myocardial infarction", 347, pp.1747~1754 (2002)
- "An official telegram of food: Common standard about general food"
- "Test on total meucury in fishes in Korea 2004"