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Extrapulmonary Small Cell Carcinoma of the Liver: Clinicopathological and Immunohistochemical Findings

김루시아|박인서|주영채|최석진|김준미|한지영|김진수|안승익
연세대학교의과대학 (Yonsei University College of Medicine)|2007.12|Yonsei Medical Journal|제48권 제6호|pp. 1066-1071

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참고문헌

주제분류의학일반

초록

Abstract

Patients with primary small cell carcinoma of the liver have rarely been described in medical literature. Knowledge of clinical, pathological and immunohistochemical properties remains limited. We described an 82-year-old female patient with primary small cell carcinoma of the liver. Histologically, the tumor showed typical morphology of a pulmonary small cell carcinoma. Immunohistochemically, the tumor revealed neuroendocrine differentiation; positive reaction for chromogranin, synaptophysin, CD56, and neuron specific enolase. The tumor was also positive for TTF-1 and c-kit but completely negative for hepatocyte, carcinoembryonic antigen, cytokeratin 7; 19; and 20. Herein, we discussed the clinical, pathological and immunohistochemical findings of extrapulmonary small cell carcinoma of the liver and reviewed the relevant literature.

참고문헌 (17)

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  13. Brenner B, "Small-cell carcinomas of the gastrointestinal tract: a review", 22, pp.2730~2739 (2004)
  14. Ordonez NG, "Value of thyroid transcription factor-1 immunostaining in distinguishing small cell lung carcinomas from other small cell carcinomas", 24, pp.1217~1223 (2000)
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