False Positive Immunoglobulin M Antibody to Cytomegalovirus in Child with Infectious Mononucleosis Caused by Epstein-Barr Virus Infection
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A 16-month-old boy was admitted because of cough that had lasted for 10 days. The patient showed severe hepatomegaly incidentally, and dual positivity of Immunoglobulin (Ig) M to Epstein-Barr virus (EBV) viral capsid antigen (VCA) and cytomegalovirus (CMV). On the basis of seroconversion to Epstein-Barr nuclear antigen (EBNA) Ig G positivity and reduced CMV Ig M titer with persistently negative CMV Ig G, a definite diagnosis of EBV-induced infectious mononucleosis was established 1 year 2 month later.
Abstract
A 16-month-old boy was admitted because of cough that had lasted for 10 days. The patient showed severe hepatomegaly incidentally, and dual positivity of Immunoglobulin (Ig) M to Epstein-Barr virus (EBV) viral capsid antigen (VCA) and cytomegalovirus (CMV). On the basis of seroconversion to Epstein-Barr nuclear antigen (EBNA) Ig G positivity and reduced CMV Ig M titer with persistently negative CMV Ig G, a definite diagnosis of EBV-induced infectious mononucleosis was established 1 year 2 month later.
참고문헌 (12)
- Sumaya CV, "Epstein-Barr virus infectious mononucleosis in children. I. Clinical and general laboratory findings", Pediatrics, 75, pp.1003~1010 (1985)
- Wakiguchi H, "Serodiagnosis of infectious mononucleosis in children", Acta Paediatr Jpn, 40, pp.328~332 (1998)
- Pullen H, "Hypersensitivity reactions to antibacterial drugs in infectious mononucleosis", Lancet, 2, pp.1176~1178 (1967)
- Ikediobi NI, "Cutaneous manifestations of Epstein- Barr virus infection", Dermatol Clin, 20, pp.283~289 (2002)
- Freigassner P, "Coinfection of the retina by Epstein-Barr virus and cytomegalovirus in an AIDS patient", Am J Ophthalmo, 134, pp.275~277 (2002)
- Polz-Dacewicz M, "CMC and EBV infections in children", Przeql Epidemiol, 56, pp.65~72 (2002)
- Sánchez Echániz J, "Mononucleosis syndromes with serology doubly positive to Epstein-Barr virus and cytomegalovirus", An Esp Pediatr, 45, pp.242~244 (1996)
- Lang D, "Cross-reactivity of Epstein-Barr virus-specific immunoglobulin M antibodies with cytomegalovirus antigens containing glycine homopolymers", Clin Diagn Lab Immunol, 8, pp.747~756 (2001)
- Bertram G, "Frequent double infection with Epstein-Barr virus and human herpesvirus-6 in patients with acute infectious mononucleosis", In Vivo, 5, pp.271~279 (1991)
- Rhodes G, "Identical IgM antibodies recognizing a glycine-alanine epitope are induced during acute infection with Epstein-Barr virus and cytomegalovirus", J Clin Lab Anal, 4, pp.456~464 (1990)
- Miendje Deyi Y, "False-positive IgM antibody tests for cytomegalovirus in patients with acute Epstein- Barr virus infection", Eur J Clin Microbiol Infect Dis, 19, pp.557~560 (2000)
- Zenda T, "Significant liver injury with dual positive IgM antibody to epstein-Barr virus and cytomegalovirus as a puzzling initial Manifestation of infectious mononucleosis", Intern Med, 43, pp.340~343 (2004)
