본문 바로가기
KERD
논문KCI 등재

Injection of Bupivacaine into Disc Space to Detect Painful Nonunion after Anterior Lumbar Interbody Fusion (ALIF) Surgery in Patients with Discogenic Low Back Pain

1

조회

0

다운로드

0

인용

0

참고문헌

키워드

주제분류의학일반

초록

Purpose: Bupivacaine is commonly used for the treatment of back pain and the diagnosis of its origin. Nonunion is sometimes observed after spinal fusion surgery;however, whether the nonunion causes pain is controversial. In the current study, we aimed to detect painful nonunion by injecting bupivacaine into the disc space of patients with nonunion after anterior lumbar interbody fusion (ALIF) surgery for discogenic low back pain. Materials and Methods: From 52 patients with low back pain, we selected 42 who showed disc degeneration at only one level (L4-L5 or L5-S1) on magnetic resonance imaging and were diagnosed by pain provocation on discography and pain relief by discoblock (the injection of bupivacaine). They underwent ALIF surgery. If the patients showed low back pain and nonunion 2 years after surgery, we injected bupivacaine into the nonuniondisc space. Patients showing pain relief after injection of bupivacaine underwentadditional posterior fixation using pedicle screws. These patients were followed up 2 years after the revision surgery. Results: Of the 42 patient subjects, 7 showed nonunion. Four of them did not show low back pain; whereas 3 showed moderate or severe low back pain. These 3 patients showed pain reductionafter injection of bupivacaine into their nonunion disc space and underwent additional posterior fixation. They showed bony union and pain relief 2 years afterthe revision surgery. Conclusion: Injection of bupivacaine into the nonunion disc space after ALIF surgery for discogenic low back pain is useful for diagnosis of the origin of pain.

Abstract

Purpose: Bupivacaine is commonly used for the treatment of back pain and the diagnosis of its origin. Nonunion is sometimes observed after spinal fusion surgery;however, whether the nonunion causes pain is controversial. In the current study, we aimed to detect painful nonunion by injecting bupivacaine into the disc space of patients with nonunion after anterior lumbar interbody fusion (ALIF) surgery for discogenic low back pain. Materials and Methods: From 52 patients with low back pain, we selected 42 who showed disc degeneration at only one level (L4-L5 or L5-S1) on magnetic resonance imaging and were diagnosed by pain provocation on discography and pain relief by discoblock (the injection of bupivacaine). They underwent ALIF surgery. If the patients showed low back pain and nonunion 2 years after surgery, we injected bupivacaine into the nonuniondisc space. Patients showing pain relief after injection of bupivacaine underwentadditional posterior fixation using pedicle screws. These patients were followed up 2 years after the revision surgery. Results: Of the 42 patient subjects, 7 showed nonunion. Four of them did not show low back pain; whereas 3 showed moderate or severe low back pain. These 3 patients showed pain reductionafter injection of bupivacaine into their nonunion disc space and underwent additional posterior fixation. They showed bony union and pain relief 2 years afterthe revision surgery. Conclusion: Injection of bupivacaine into the nonunion disc space after ALIF surgery for discogenic low back pain is useful for diagnosis of the origin of pain.

참고문헌 (21)

  1. Nachemson AL, "The lumbar spine, an orthopaedic challenge", Spine, 1, pp.59~71 (1976)
  2. Mooney V, "Presidential address. International Society for the Study of the Lumbar Spine. Dallas, 1986. Where is the pain coming from?", Spine (Phila Pa 1976), 12, pp.754~759 (1987)
  3. Deyo RA, "Low back pain", N Engl J Med, 344, pp.363~370 (2001)
  4. Pauza KJ, "A randomized, placebo-controlled trial of intradiscal electrothermal therapy for the treatment of discogenic low back pain", Spine J, 4, pp.27~35 (2004)
  5. Shuff C, "Artificial disc replacement: the new solution for discogenic low back pain?", Am J Orthop (Belle Mead NJ), 34, pp.8~12 (2005)
  6. Buenaventura RM, "Systematic review of discography as a diagnostic test for spinal pain: an update", Pain Physician, 10, pp.147~164 (2007)
  7. Carragee EJ, "A gold standard evaluation of the “discogenic pain” diagnosis as determined by provocative discography", Spine (Phila Pa 1976), 31, pp.2115~2123 (2006)
  8. Ohtori S, "Results of surgery for discogenic low back pain: a randomized study using discography versus discoblock for diagnosis", Spine (Phila Pa 1976), 34, pp.1345~1348 (2009)
  9. Ohtori S, "Surgical versus nonsurgical treatment of selected patients with discogenic low back pain: a small-sized randomized trial", Spine (Phila Pa 1976), 36, pp.347~354 (2011)
  10. Mirza SK, "Systematic review of randomized trials comparing lumbar fusion surgery to nonoperative care for treatment of chronic back pain", Spine (Phila Pa 1976), 32, pp.816~823 (2007)
  11. Fischgrund JS, "1997 Volvo Award winner in clinical studies. Degenerative lumbar spondylolisthesis with spinal stenosis: a prospective, randomized study comparing decompressive laminectomy and arthrodesis with and without spinal instrumentation", Spine (Phila Pa 1976), 22, pp.2807~2812 (1997)
  12. Herkowitz HN, "Degenerative lumbar spondylolisthesis with spinal stenosis. A prospective study comparing decompression with decompression and intertransverse process arthrodesis", J Bone Joint Surg Am, 73, pp.802~808 (1991)
  13. Ploumis A, "Disc space injection with marcaine as a method to evaluate painful nonunion of an interbody fusion device: a case report", Spine J, 7, pp.74~78 (2007)
  14. Vamvanij V, "Surgical treatment of internal disc disruption: an outcome study of four fusion tec hniques", J Spinal Disord, 11, pp.375~382 (1998)
  15. Chu CR, "In vitro exposure to 0.5% bupivacaine is cytotoxic to bovine articular chondrocytes", Arthroscopy, 22, pp.693~699 (2006)
  16. Dogan N, "The effects of bupivacaine and neostigmine on articular cartilage and synovium in the rabbit knee joint", J Int Med Res, 32, pp.513~519 (2004)
  17. Gomoll AH, "Chondrolysis after continuous intra-articular bupivacaine infusion: an experimental model investigating chondrotoxicity in the rabbit shoulder", Arthroscopy, 22, pp.813~819 (2006)
  18. Lee H, "Effect of bupivacaine on intervertebral disc cell viability", Spine J, 10, pp.159~166 (2010)
  19. Wang D, "Bupivacaine decreases cell viability and matrix protein synthesis in an intervertebral disc organ model system", Spine J, 11, pp.139~146 (2011)
  20. Chu CR, "In vivo effects of single intra-articular injection of 0.5% bupivacaine on articular cartilage", J Bone Joint Surg Am, 92, pp.599~608 (2010)
  21. Ohtori S, "No acceleration of intervertebral disc degeneration after a single injection of bupivacaine in young age group with follow-up of 5 years", Asian Spine J, 7, pp.212~217 (2013)

관련 논문AI추천

Efficacy of transforaminal laser annuloplasty versus intradiscal radiofrequency annuloplasty for discogenic low back painChan Hong Park, Kyoung Kyu Lee, Sang Ho Lee대한통증학회 · The Korean Journal of Pain2019 · 제32권 제2호What is the Role of Epidural Injections in the Treatment of Lumbar Discogenic Pain: A Systematic Review of Comparative Analysis with FusionDevi E. Nampiaparampil, Joshua A. Hirsch, Laxmaiah Manchikanti, Peter S. Staats대한통증학회 · The Korean Journal of Pain2015 · 제28권 제2호Effect of Intradiscal Methylene Blue Injection for the Chronic Discogenic Low Back Pain: One Year Prospective Follow-up Study김수현, 안상호, 이동규, 조윤우대한재활의학회 · Annals of Rehabilitation Medicine2012 · 제36권 제5호Effect of Intradiscal Monopolar Pulsed Radiofrequency on Chronic Discogenic Back Pain Diagnosed by Pressure-Controlled Provocative Discography: A One Year Prospective Study안상호, 이동규, 정용재, 조윤우대한재활의학회 · Annals of Rehabilitation Medicine2012 · 제36권 제5호The Comparison of the Result of Epiduroscopic Laser Neural Decompression between FBSS or Not김응돈, 오현진, 조대현대한통증학회 · The Korean Journal of Pain2014 · 제27권 제1호Analysis of the Correlation Among Age, Disc Morphology, Positive Discography and Prognosis in Patients With Chronic Low Back Pain김성민, 이보람, 이상헌, 황정원대한재활의학회 · Annals of Rehabilitation Medicine2015 · 제39권 제3호

이 간행물의 다른 논문 (19건)