Multidisciplinary Team Approach for Identifying Potential Candidate for Transcatheter Aortic Valve Implantation
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Purpose: We sought to evaluate the clinical usefulness of decision making by a multidisciplinary heart team for identifying potential candidates for transcatheter aortic valve implantation (TAVI) in patients with symptomatic severe aortic stenosis. Materials and Methods: The multidisciplinary team consisted of two interventionalcardiologists, two cardiovascular surgeons, one cardiac imaging specialist,and two cardiac anesthesiologists. Results: Out of 60 patients who were screened as potential TAVI candidates, 31 patients were initially recommended as appropriate for TAVI, and 20 of these 31 eventually underwent TAVI. Twenty-two patients underwent surgical aortic valve replacement (AVR), and 17 patients receivedonly medical treatment. Patients who underwent TAVI and medical therapy were older than those who underwent surgical AVR (p<0.001). The logistic Euroscorewas significantly highest in the TAVI group and lowest in the surgical AVR group (p=0.012). Most patients in the TAVI group (90%) and the surgical AVR group (91%) had severe cardiac symptoms, but only 47% in the medical therapy group had severe symptoms. The cumulative percentages of survival without re-hospitalization or all-cause death at 6 months for the surgical AVR, TAVI, and medical therapy groups were 84%, 75%, and 28%, respectively (p=0.007, by log-rank). Conclusion: TAVI was recommended in half of the potential candidates followinga multidisciplinary team approach and was eventually performed in one-third of these patients. One-third of the patients who were initially considered potential candidates received surgical AVR with favorable clinical outcomes.
Abstract
Purpose: We sought to evaluate the clinical usefulness of decision making by a multidisciplinary heart team for identifying potential candidates for transcatheter aortic valve implantation (TAVI) in patients with symptomatic severe aortic stenosis. Materials and Methods: The multidisciplinary team consisted of two interventionalcardiologists, two cardiovascular surgeons, one cardiac imaging specialist,and two cardiac anesthesiologists. Results: Out of 60 patients who were screened as potential TAVI candidates, 31 patients were initially recommended as appropriate for TAVI, and 20 of these 31 eventually underwent TAVI. Twenty-two patients underwent surgical aortic valve replacement (AVR), and 17 patients receivedonly medical treatment. Patients who underwent TAVI and medical therapy were older than those who underwent surgical AVR (p<0.001). The logistic Euroscorewas significantly highest in the TAVI group and lowest in the surgical AVR group (p=0.012). Most patients in the TAVI group (90%) and the surgical AVR group (91%) had severe cardiac symptoms, but only 47% in the medical therapy group had severe symptoms. The cumulative percentages of survival without re-hospitalization or all-cause death at 6 months for the surgical AVR, TAVI, and medical therapy groups were 84%, 75%, and 28%, respectively (p=0.007, by log-rank). Conclusion: TAVI was recommended in half of the potential candidates followinga multidisciplinary team approach and was eventually performed in one-third of these patients. One-third of the patients who were initially considered potential candidates received surgical AVR with favorable clinical outcomes.
참고문헌 (19)
- Nkomo VT, "Burden of valvular heart diseases: a population-based study", Lancet, 368, pp.1005~1011 (2006)
- Bonow RO, "2008 focused update incorporated into the ACC", AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology, J Am Coll Cardiol, pp.2008, 52[DOI]
- Iung B, "A prospective survey of patients with valvular heart disease in Europe: The Euro Heart Survey on Valvular Heart Disease", Eur Heart J, 24, pp.1231~1243 (2003)
- Freed BH, "Reasons for nonadherence to guidelines for aortic valve replacement in patients with severe aortic stenosis and potential solutions", Am J Cardiol, 105, pp.1339~1342 (2010)
- Osswald BR, "Overestimation of aortic valve replacement risk by EuroSCORE: implications for percutaneous valve replacement", Eur Heart J, 30, pp.74~80 (2009)
- Leontyev S, "Aortic valve replacement in octogenarians: utility of risk stratification with EuroSCORE", Ann Thorac Surg, 87, pp.1440~1445 (2009)
- Piazza N, "Relationship between the logistic EuroSCORE and the Society of Thoracic Surgeons Predicted Risk of Mortality score in patients implanted with the CoreValve ReValving system--a Bern-Rotterdam Study", Am Heart J, 159, pp.323~329 (2010)
- Kempfert J, "Transapical aortic valve implantation: analysis of risk factors and learning experience in 299 patients", Circulation, 124(11 Suppl), pp.S124~S129 (2011)
- Kappetein AP, "Updated standardized endpoint definitions for transcatheter aortic valve implantation: the Valve Academic Research Consortium-2 consensus document", J Am Coll Cardiol, 60, pp.1438~1454 (2012)
- Alli OO, "Transcatheter aortic valve implantation: assessing the learning curve", JACC Cardiovasc Interv, 5, pp.72~79 (2012)
- Gurvitch R, "Transcatheter aortic valve implantation: lessons from the learning curve of the first 270 high-risk patients", Catheter Cardiovasc Interv, 78, pp.977~984 (2011)
- Grube E, "Percutaneous aortic valve replacement for severe aortic stenosis in high-risk patients using the second- and current third-generation self-expanding CoreValve prosthesis: device success and 30-day clinical outcome", J Am Coll Cardiol, 50, pp.69~76 (2007)
- Sinning JM, "Renal function as predictor of mortality in patients after percutaneous transcatheter aortic valve implantation", JACC Cardiovasc Interv, 3, pp.1141~1149 (2010)
- 임의, "Comparison of Early Clinical Outcomes Following Transcatheter Aortic Valve Implantation versus Surgical Aortic Valve Replacement versus Optimal Medical Therapy in Patients Older than 80 Years with Symptomatic Severe Aortic Stenosis", Yonsei Medical Journal, 54(3), pp.596~602 (2013), 연세대학교의과대학[DOI]
- Cribier A, "Early experience with percutaneous transcatheter implantation of heart valve prosthesis for the treatment of end-stage inoperable patients with calcific aortic stenosis", J Am Coll Cardiol, 43, pp.698~703 (2004)
- Webb JG, "Percutaneous transarterial aortic valve replacement in selected high-risk patients with aortic stenosis", Circulation, 116, pp.755~763 (2007)
- Smith CR, "Transcatheter versus surgical aortic-valve replacement in high-risk patients", N Engl J Med, 364, pp.2187~2198 (2011)
- Dworakowski R, "Transcatheter aortic valve implantation for severe aortic stenosis-a new paradigm for multidisciplinary intervention: a prospective cohort study", Am Heart J, 160, pp.237~243 (2010)
- Bach DS, "Unoperated patients with severe aortic stenosis", J Am Coll Cardiol, 50, pp.2018~2019 (2007)
