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Obesity Is Not Associated with Increased Operative Complications in Single-Site Robotic Partial Nephrectomy

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초록

Purpose: To evaluate the impact of high body mass index (BMI) on outcomes followingrobotic laparoendoscopic single-site surgery (R-LESS) robotic-assisted laparoscopicpartial nephrectomy (RPN). Materials and Methods: Data from 83 Koreanpatients who had undergone robotic partial nephrectomy from 2006 to 2014 were retrospectively analyzed. The subjects were stratified into two groups accordingto WHO definitions for the Asian population, consisting of 56 normal range (BMI=18.5‒24.99 kg/m2) and 27 obese (≥25 kg/m2) patients. Outcome measurementsincluded Trifecta achievement and the perioperative and postoperative comparisonbetween high and normal BMI series. The measurements were estimated and analyzed with SPSS version 17. Results: Tumor’s complexity characteristics (R.E.N.A.L. score, tumor size) of both groups were similar. No significant differencesexisted between the two groups with regard to operative time (p=0.27), warm ischemia time (p=0.35) estimated blood loss (p=0.42), transfusion rate (p=0.48) renalfunction following up for 1 year, positive margins (p=0.24) and postoperative complication rate (p=0.34). Trifecta was achieved in 5 (18.5%) obese and 19 (33.9%) normal weight patients, respectively (p=0.14). In multivariable analysis, only tumor size was significantly correlated with the possibility of Trifecta accomplishment. Conclusion: Our findings suggest that R-LESS RPN can be effectively and safely performed in patients with increased BMI, since Trifecta rate, and perioperativeand postoperative outcomes are not significantly different in comparison to normal weight subjects.

Abstract

Purpose: To evaluate the impact of high body mass index (BMI) on outcomes followingrobotic laparoendoscopic single-site surgery (R-LESS) robotic-assisted laparoscopicpartial nephrectomy (RPN). Materials and Methods: Data from 83 Koreanpatients who had undergone robotic partial nephrectomy from 2006 to 2014 were retrospectively analyzed. The subjects were stratified into two groups accordingto WHO definitions for the Asian population, consisting of 56 normal range (BMI=18.5‒24.99 kg/m2) and 27 obese (≥25 kg/m2) patients. Outcome measurementsincluded Trifecta achievement and the perioperative and postoperative comparisonbetween high and normal BMI series. The measurements were estimated and analyzed with SPSS version 17. Results: Tumor’s complexity characteristics (R.E.N.A.L. score, tumor size) of both groups were similar. No significant differencesexisted between the two groups with regard to operative time (p=0.27), warm ischemia time (p=0.35) estimated blood loss (p=0.42), transfusion rate (p=0.48) renalfunction following up for 1 year, positive margins (p=0.24) and postoperative complication rate (p=0.34). Trifecta was achieved in 5 (18.5%) obese and 19 (33.9%) normal weight patients, respectively (p=0.14). In multivariable analysis, only tumor size was significantly correlated with the possibility of Trifecta accomplishment. Conclusion: Our findings suggest that R-LESS RPN can be effectively and safely performed in patients with increased BMI, since Trifecta rate, and perioperativeand postoperative outcomes are not significantly different in comparison to normal weight subjects.

참고문헌 (22)

  1. MacLennan S, "Systematic review of oncological outcomes following surgical management of localised renal cancer", Eur Urol, 61, pp.972~993 (2012)
  2. Porter MP, "Trends in renal cancer surgery and patient provider characteristics associated with partial nephrectomy in the United States", Urol Oncol, 25, pp.298~302 (2007)
  3. Aboumarzouk OM, "Robotic versus laparoscopic partial nephrectomy: a systematic review and meta-analysis", Eur Urol, 62, pp.1023~1033 (2012)
  4. Park SK, "Patient-reported body image and cosmesis outcomes following kidney surgery: comparison of laparoendoscopic single-site, laparoscopic, and open surgery", Eur Urol, 60, pp.1097~1104 (2011)
  5. Ljungberg B, "EAU guidelines on renal cell carcinoma: the 2010 update", Eur Urol, 58, pp.398~406 (2010)
  6. Fugita OE, "Laparoscopic radical nephrectomy in obese patients: outcomes and technical considerations", Urology, 63, pp.247~252 (2004)
  7. Isac WE, "The impact of body mass index on surgical outcomes of robotic partial nephrectomy", BJU Int, 110(11 Pt C), pp.E997~E1002 (2012)
  8. Naeem N, "Robot-assisted partial nephrectomy in obese patients", J Endourol, 25, pp.101~105 (2011)
  9. Kiziloz H, "The impact of body mass index on perioperative outcomes in robot-assisted laparoscopic partial nephrectomy", J Endourol, 27, pp.1000~1007 (2013)
  10. "The Asia-Pacific Perspective: Redefining Obesity and its Treatment" (2000)[URL]
  11. Komninos C, "R-LESS partial nephrectomy trifecta outcome is inferior to multiport robotic partial nephrectomy: comparative analysis", Eur Urol, 66, pp.512~517 (2014)
  12. Dindo D, "Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey", Ann Surg, 240, pp.205~213 (2004)
  13. Kutikov A, "The R.E.N.A.L. nephrometry score: a comprehensive standardized system for quantitating renal tumor size, location and depth", J Urol, 182, pp.844~853 (2009)
  14. Levey AS, "A more accurate method to estimate glomerular filtration rate from serum creatinine: a new prediction equation. Modification of Diet in Renal Disease Study Group", Ann Intern Med, 130, pp.461~470 (1999)
  15. Jeon HG, "Initial experience with 50 laparoendoscopic single site surgeries using a homemade, single port device at a single center", J Urol, 183, pp.1866~1871 (2010)
  16. Buffi N, "Margin, ischemia, and complications (MIC) score in partial nephrectomy: a new system for evaluating achievement of optimal outcomes in nephron-sparing surgery", Eur Urol, 62, pp.617~618 (2012)
  17. Mottrie AM, "Editorial comment on: Margin, ischemia, and complications (MIC) score in partial nephrectomy: a new system for evaluating achievement of optimal outcomes in nephron-sparing surgery", Eur Urol, 62, pp.617~618 (2012)
  18. Hung AJ, "“Trifecta” in partial nephrectomy", J Urol, 189, pp.36~42 (2013)
  19. Khalifeh A, "Comparative outcomes and assessment of trifecta in 500 robotic and laparoscopic partial nephrectomy cases: a single surgeon experience", J Urol, 189, pp.1236~1242 (2013)
  20. Colombo JR Jr, "Laparoscopic partial nephrectomy in obese patients", Urology, 69, pp.44~48 (2007)
  21. Klinghoffer Z, "Obesity and renal cell carcinoma: epidemiology, underlying mechanisms and management considerations", Expert Rev Anticancer Ther, 9, pp.975~987 (2009)
  22. Aboumarzouk OM, "Laparoscopic partial nephrectomy in obese patients: a systematic review and meta-analysis", BJU Int, 110, pp.1244~1250 (2012)

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