Noninfectious Complications of Peritoneal Dialysis in Korean Children: A 26-Year Single-Center Study
0
조회
0
다운로드
2
인용
0
참고문헌
키워드
초록
Purpose: The aim of this study was to investigate noninfectious complications of peritoneal dialysis (PD), including mechanical and metabolic complications, at a single center in Korea. Materials and Methods: We analyzed data from 60 PD patients aged ≤18 years (40 boys and 20 girls) during the period between 1986 and 2012. The collected data included gender, age, causes of PD, incidence of noninfectious complications, and treatment for the complications. Results: The mean duration of PD therapy was 28.7±42.1 months (range 1–240 months). The most common cause of end-stage renal disease was glomerular disease (43.3%). There were no statistically significant differences between patients with and withoutmechanical complications regarding gender, age at the start of PD, and total duration of PD. Outflow failure was the most common catheter-related complication (14.3%), followed by leakage (10.0%) and hernia (8.6%). Metabolic complications, such as hyperglycemia and hypokalemia, were observed in three of 16 patients. The frequency of noninfectious complications of PD in our study was comparable with those in previous pediatric studies. PD was switched to hemodialysis (HD) in only three patients. Conclusion: Our results indicate that noninfectious complications of PD are common, though they hardly lead to catheter removalor HD in pediatric patients on PD.
Abstract
Purpose: The aim of this study was to investigate noninfectious complications of peritoneal dialysis (PD), including mechanical and metabolic complications, at a single center in Korea. Materials and Methods: We analyzed data from 60 PD patients aged ≤18 years (40 boys and 20 girls) during the period between 1986 and 2012. The collected data included gender, age, causes of PD, incidence of noninfectious complications, and treatment for the complications. Results: The mean duration of PD therapy was 28.7±42.1 months (range 1–240 months). The most common cause of end-stage renal disease was glomerular disease (43.3%). There were no statistically significant differences between patients with and withoutmechanical complications regarding gender, age at the start of PD, and total duration of PD. Outflow failure was the most common catheter-related complication (14.3%), followed by leakage (10.0%) and hernia (8.6%). Metabolic complications, such as hyperglycemia and hypokalemia, were observed in three of 16 patients. The frequency of noninfectious complications of PD in our study was comparable with those in previous pediatric studies. PD was switched to hemodialysis (HD) in only three patients. Conclusion: Our results indicate that noninfectious complications of PD are common, though they hardly lead to catheter removalor HD in pediatric patients on PD.
참고문헌 (23)
- Warady BA, "Optimal care of the infant, child, and adolescent on dialysis: 2014 update", Am J Kidney Dis, 64, pp.128~142 (2014)
- McCormick BB, "Noninfectious complications of peritoneal dialysis: implications for patient and technique survival", J Am Soc Nephrol, 18, pp.3023~3025 (2007)
- Kim PK, "Pediatric peritoneal dialysis in Korea: practical solutions to the problems of peritoneal dialysis for children", Perit Dial Int, 19(Suppl 2), pp.S489~S492 (1999)
- Park SC, "Complications of Continuous Ambulatory Peritoneal Dialysis in Children", J Korean Assoc Pediatr Surg, 9, pp.77~80 (2003)
- 이경옥, "Outcomes of Peritonitis in Children on Peritoneal Dialysis: A 25-Year Experience at Severance Hospital", Yonsei Medical Journal, 54(4), pp.983~989 (2013), 연세대학교의과대학[DOI]
- Hooman N, "The outcome of Iranian children on continuous ambulatory peritoneal dialysis: the first report of Iranian National Registry", Arch Iran Med, 12, pp.24~28 (2009)
- Aksu N, "A tenyear single-centre experience in children on chronic peritoneal dialysis--significance of percutaneous placement of peritoneal dialysis catheters", Nephrol Dial Transplant, 22, pp.2045~2051 (2007)
- Rinaldi S, "Chronic peritoneal dialysis catheters in children: a fifteen-year experience of the Italian Registry of Pediatric Chronic Peritoneal Dialysis", Perit Dial Int, 24, pp.481~486 (2004)
- Rahim KA, "Risk factors for catheter-related complications in pediatric peritoneal dialysis", Pediatr Nephrol, 19, pp.1021~1028 (2004)
- Kim HS, "Comparison of the laparoscopic and open peritoneal dialysis catheter insertion in children", J Korean Assoc Pediatr Surg, 17, pp.125~132 (2011)
- Saha TC, "Noninfectious complications of peritoneal dialysis", South Med J, 100, pp.54~58 (2007)
- 하일수, "소아의 복막투석", Korean Journal of Pediatrics, 52(10), pp.1069~1074 (2009), 대한소아과학회
- Macchini F, "Chronic peritoneal dialysis in children: catheter related complications. A single centre experience", Pediatr Surg Int, 22, pp.524~528 (2006)
- Negoi D, "Current trends in the use of peritoneal dialysis catheters", Adv Perit Dial, 22, pp.147~152 (2006)
- Flanigan M, "Peritoneal catheters and exit-site practices toward optimum peritoneal access: a review of current developments", Perit Dial Int, 25, pp.132~139 (2005)
- 정수인, "소아에서 복막투석도관 삽입시 복강경을 이용한 방법과 기존의 수술법에 따른 초기 합병증 발생의 차이", Childhood Kidney Diseases, 11(1), pp.51~58 (2007), 대한소아신장학회
- 홍석균, "시행한 복강경 복막 투석 도관 삽입술과 개복 삽입술의 비교 연구", 대한내시경복강경외과학회지, 14(2), pp.106~110 (2011), 대한내시경복강경외과학회
- Stringel G, "Laparoscopic placement of peritoneal dialysis catheters in children", J Pediatr Surg, 43, pp.857~860 (2008)
- Boyer J, "Hyperglycemia and hyperosmolality complicating peritoneal dialysis", Ann Intern Med, 67, pp.568~572 (1967)
- Bakkaloglu SA, "The effect of CAPD on the lipid profile of pediatric patients", Perit Dial Int, 20, pp.568~571 (2000)
- Holmes C, "Glucose sparing in peritoneal dialysis: implications and metrics", Kidney Int Suppl, pp.S104~S109 (2006)
- von Lilien T, "Five years’ experience with continuous ambulatory or continuous cycling peritoneal dialysis in children", J Pediatr, 111, pp.513~518 (1987)
- Schaefer F, "Current practice of peritoneal dialysis in children: results of a longitudinal survey. Mid European Pediatric Peritoneal Dialysis Study Group (MEPPS)", Perit Dial Int, 19(Suppl 2), pp.S445~S449 (1999)