A Case of COVID-19 in a 45-Day-Old Infant with Persistent Fecal Virus Shedding for More Than 12 Weeks
0
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
In this report, we describe the case of a SARS-CoV-2 infection (COVID-19) in an infant with mild fever and diarrhea in the absence of respiratory distress. A 45-day-old male infant with COVID-19 was transferred to our pediatric department. He had mild fever and diarrhea at admission. Positive-to-negative nasal swab conversion occurred on the 21st day from the onset of symptoms. However, stool swab positivity persisted during the 6-week admission period and for 7 weeks during follow-up at an outpatient clinic after discharge. Negative conversion in a stool specimen occurred on the 142nd day from the onset of symptoms. This case highlights the potential of fecal virus shedding as an important feature of viral transmission in infants and young children.
Abstract
In this report, we describe the case of a SARS-CoV-2 infection (COVID-19) in an infant with mild fever and diarrhea in the absence of respiratory distress. A 45-day-old male infant with COVID-19 was transferred to our pediatric department. He had mild fever and diarrhea at admission. Positive-to-negative nasal swab conversion occurred on the 21st day from the onset of symptoms. However, stool swab positivity persisted during the 6-week admission period and for 7 weeks during follow-up at an outpatient clinic after discharge. Negative conversion in a stool specimen occurred on the 142nd day from the onset of symptoms. This case highlights the potential of fecal virus shedding as an important feature of viral transmission in infants and young children.
참고문헌 (11)
- Weiss SR, "Coronavirus pathogenesis and the emerging pathogen severe acute respiratory syndrome coronavirus", Microbiol Mol Biol Rev, 69, pp.635~664 (2005)
- De Rose DU, "Novel coronavirus disease(COVID-19)in newborns and infants : what we know so far", Ital J Pediatr, 46, pp.56~ (2020)
- Chen ZM, "Diagnosis and treatment recommendations for pediatric respiratory infection caused by the 2019 novel coronavirus", World J Pediatr, 16, pp.240~246 (2020)
- Kam KQ, "A well infant with coronavirus disease 2019 with high viral load", Clin Infect Dis, 71, pp.847~849 (2020)
- . Available at: https:, , doi.org, 2020.01.30.927806, pp.2020, ~
- Cao Q, "SARS-CoV-2 infection in children : transmission dynamics and clinical characteristics", J Formos Med Assoc, 119, pp.670~673 (2020)
- Zou L, "SARSCoV-2 viral load in upper respiratory specimens of infected patients", N Engl J Med, 382, pp.1177~1179 (2020)
- Bai Y, "Presumed asymptomatic carrier transmission of COVID-19", JAMA, 323, pp.1406~1407 (2020)
- Tong ZD, "Potential presymptomatic transmission of SARS-CoV-2, Zhejiang Province, China, 2020", Emerg Infect Dis, 26, pp.1052~1054 (2020)
- Zhou F, "Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China : a retrospective cohort study", Lancet, 395, pp.1054~1062 (2020)
- Xiao F, "Evidence for gastrointestinal infection of SARS-CoV-2", Gastroenterology, 158, pp.1831~1833 (2020)
