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Clinical Characteristics of Patients Who Contracted the SARS-CoV-2 Omicron Variant from an Outbreak in a Single Hospital

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초록

There are few studies on the severity and prognosis of patients infected with the severe acute respiratory syndrome-coronavirus-2(SARS-CoV-2) omicron variant. From January 11, 2022 to January 25, 2022, 181 patients were infected with the SARS-CoV-2 omi cron variant in a single hospital in Korea. The initial clinical characteristics were investigated through the COVID-19 basic investi gation form. Outcomes were reviewed using medical records. The median age of the patients was 57 years (range 1–90), and 95patients (52.5%) were male. None were re-infected with SARS-CoV-2, and 127 (70.2%) were fully vaccinated (boosted or within 6months after second vaccination). Forty-two patients (23.2%) were asymptomatic. Among symptomatic patients, the frequencyof symptoms was as follows: cough (37.0%), sore throat (33.7%), and fever (30.4%). In terms of disease severity, 168 (92.8%) pa tients did not require supplemental oxygen, 6 (3.3%) required low-flow oxygen, 5 (2.8%) required high-flow oxygen, and 2 (1.1%)died. Four of the five individuals who required high-flow oxygen and the two who died were not vaccinated. Most of the patientswho contracted the SARS-CoV-2 omicron variant exhibited mild clinical features; however, severe clinical features including mor tality were encountered among individuals who were not vaccinated.

Abstract

There are few studies on the severity and prognosis of patients infected with the severe acute respiratory syndrome-coronavirus-2(SARS-CoV-2) omicron variant. From January 11, 2022 to January 25, 2022, 181 patients were infected with the SARS-CoV-2 omi cron variant in a single hospital in Korea. The initial clinical characteristics were investigated through the COVID-19 basic investi gation form. Outcomes were reviewed using medical records. The median age of the patients was 57 years (range 1–90), and 95patients (52.5%) were male. None were re-infected with SARS-CoV-2, and 127 (70.2%) were fully vaccinated (boosted or within 6months after second vaccination). Forty-two patients (23.2%) were asymptomatic. Among symptomatic patients, the frequencyof symptoms was as follows: cough (37.0%), sore throat (33.7%), and fever (30.4%). In terms of disease severity, 168 (92.8%) pa tients did not require supplemental oxygen, 6 (3.3%) required low-flow oxygen, 5 (2.8%) required high-flow oxygen, and 2 (1.1%)died. Four of the five individuals who required high-flow oxygen and the two who died were not vaccinated. Most of the patientswho contracted the SARS-CoV-2 omicron variant exhibited mild clinical features; however, severe clinical features including mor tality were encountered among individuals who were not vaccinated.

참고문헌 (14)

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