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Characteristics and Treatment Outcomes of Transition among Patients with Inflammatory Bowel Disease

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Purpose: This study aimed to assess disease characteristics and outcomes of transition in patient care among adolescent patients with inflammatory bowel disease (IBD). Materials and Methods: Data from patients younger than 18 years who were diagnosed with IBD (Crohn’s disease, ulcerative colitis, or intestinal Behçet’s disease) were investigated. We categorized the patients into two groups: transition IBD group (Group A, diagnosed in pediatric care followed by transfer to/attendance in adult IBD care) and non-transition group (Group B, diag nosed and followed up in pediatric care or adult IBD care without transfer). Results: Data from a total of 242 patients [Group A (n=29, 12.0%), Group B (n=213, 88.0%)] were analyzed. A significantly higher number of patients was diagnosed at an earlier age in Group A than in Group B (p<0.001). Group A patients had more severe dis ease in terms of number of disease flare ups (p=0.011) and frequency of bowel-related complications (p<0.001). Multiple linear re gression analysis showed that Group B patients had more medical non-compliance than Group A patients (β=2.31, p=0.018). After transition, IBD-related admission frequency, emergency admission frequency, disease flare frequency, and medical non-compli ance were significantly improved. Conclusion: The transition IBD group had more severe disease. Medical non-compliance was lower in the transition IBD group. Clinical outcomes improved after transition.

Abstract

Purpose: This study aimed to assess disease characteristics and outcomes of transition in patient care among adolescent patients with inflammatory bowel disease (IBD). Materials and Methods: Data from patients younger than 18 years who were diagnosed with IBD (Crohn’s disease, ulcerative colitis, or intestinal Behçet’s disease) were investigated. We categorized the patients into two groups: transition IBD group (Group A, diagnosed in pediatric care followed by transfer to/attendance in adult IBD care) and non-transition group (Group B, diag nosed and followed up in pediatric care or adult IBD care without transfer). Results: Data from a total of 242 patients [Group A (n=29, 12.0%), Group B (n=213, 88.0%)] were analyzed. A significantly higher number of patients was diagnosed at an earlier age in Group A than in Group B (p<0.001). Group A patients had more severe dis ease in terms of number of disease flare ups (p=0.011) and frequency of bowel-related complications (p<0.001). Multiple linear re gression analysis showed that Group B patients had more medical non-compliance than Group A patients (β=2.31, p=0.018). After transition, IBD-related admission frequency, emergency admission frequency, disease flare frequency, and medical non-compli ance were significantly improved. Conclusion: The transition IBD group had more severe disease. Medical non-compliance was lower in the transition IBD group. Clinical outcomes improved after transition.

참고문헌 (35)

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관련 논문AI추천

Successful Transition from Pediatric to Adult Care in Inflammatory Bowel Disease: What is the Key?Byong Duk Ye, Jeongseok Kim대한소아소화기영양학회 · Pediatric Gastroenterology, Hepatology & Nutrition2019 · 제22권 제1호Clinical Aspects and Treatments for Pediatric Inflammatory Bowel DiseasesJin Soo Moon대한소아소화기영양학회 · Pediatric Gastroenterology, Hepatology & Nutrition2019 · 제22권 제1호Higher Morbidity of Monogenic Inflammatory Bowel Disease Compared to the Adolescent Onset Inflammatory Bowel Disease문진수, Eun Joo Lee, Hye Ran Yang, Jae Sung Ko, Ju Whi Kim, Ju Young Jang, Kwang Yeon Kim대한소아소화기영양학회 · Pediatric Gastroenterology, Hepatology & Nutrition2018 · 제21권 제1호Features and Outcomes of Children with Ulcerative Colitis who Undergo a Diagnostic Change: A Single-Center ExperienceHirotaka Shimizu, Ichiro Takeuchi, Katsuhiro Arai, Masaaki Usami, Natsuki Ito, Reiko Kyodo, Takuro Sato, Toshiaki Shimizu, Yuri Hirano대한소아소화기영양학회 · Pediatric Gastroenterology, Hepatology & Nutrition2021 · 제24권 제4호Quality of Life in Children and Adolescents with Inflammatory Bowel Disease: Impact and Predictive FactorsElisa de Carvalho, Larissa Caetano Silva, Renata B.P. Melo Seixas대한소아소화기영양학회 · Pediatric Gastroenterology, Hepatology & Nutrition2020 · 제23권 제3호Infliximab Therapy for Children with Moderate to Severe Ulcerative Colitis: A Step-Up versus a Top-Down Strategy강빈, 김미진, 김은실, 최연호연세대학교의과대학 · Yonsei Medical Journal2021 · 제62권 제7호

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