피크노제놀 성분이 한국 10~20대 여드름 피부에 미치는 영향
The effect pycnogenol has on the acne skin of Koreans in their 10s and 20s
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초록
프랑스 해송 껍질추출물인 피크노제놀은 항염, 항혈전, 혈압조절 효과, 면역조절 효과 등의 다양한 의학적 연구결과를 바탕으로 건강식품 소재로 활용되고 있으며 최근 화장품 소재로도 활용되고 있지만 피부 유효성에 관한 임상 연구는 미미한 실정이다. 본 연구는 피크노제놀 성분을 화장품에 적용하여 10~20대 여드름 피부에 미치는 효과를 피부 임상학적으로 접근하여 그 유효성을 연구하고자 하였으며, 피크노제놀 0.2% 첨가 화장품과 무첨가 화장품을 각 그룹별 11명의 임상자가 참여하여 6주 동안 사용하게 한 후 여드름 피부 상태변화를 살펴보았다. 피크노제놀을 함유한 화장품을 사용한 그룹에서 여드름 균(P-Acnes)의 대사산물인 포비린 지수가 감소하였으며 홍조와 색소침착 지수가 감소하는 효과가 있었다. 본 연구를 통하여 피크노제놀 성분이 여드름 균을 감소시키고 여드름 피부에 나타나는 홍조와 색소침착 증상을 완화하는 효과가 있는 화장품 소재인 것을 확인하였다.
Abstract
Pycnogenol is used as a dietary supplement based on various medical research studies suggesting health benefits. In recent years, it has also been used in cosmetic products, but the clinical research on its dermatologic effects has been insufficient. This study was designed to determine the effectiveness of pycnogenol topically applied to skin of individuals with acne in their teens and twenties. Cosmetics containing 0.2% pycnogenol were applied to a group of 11 clinical subjects for 6 weeks and their skin conditions were assessed. The group that used cosmetics with pycnogenol showed decrease in P-Acnes, acne causing bacteria, phorphyrin index, a metabolite, and the pigmentation and redness index. This study confirms that pycnogenol extract is effective dermatologically in decreasing acne bacteria and reducing redness and pigmentation of skin affected by acne.
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