Establishment of analytical methods for allergenic compounds in mouthwashes and sanitary napkins by ultra-high-performance liquid chromatography with tandem mass spectrometry
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Analytical methods for detecting atranol, chloroatranol, evernic acid, (+)-usnic acid, and atranorin in sanitary napkins and mouthwashes were developed using ultrahigh performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS). UHPLC-MS/MS conditions were optimized for rapid, sensitive, and simultaneous analysis of the five allergenic compounds. The methods were validated by assessing their specificity, matrix effects, limit of detection (LOD), limit of quantification (LOQ), linearity, accuracy, and precision. Good linearity was achieved with a determination coefficient of ≥0.99. The LOD and LOQ were 2.1-9.8 and 6.4-29.6 ng/g for sanitary napkins and 0.29-0.48 and 0.87-1.45 ng/mL for mouthwashes, respectively. The accuracy and precision were within an acceptable range according to the criteria reported in the European SANTE/11813/2017 guidelines (70-120 % recovery, <20 % relative standard deviation). Therefore, these methods can be used to analyze atranol, chloroatranol, evernic acid, (+)-usnic acid, and atranorin in sanitary napkins and mouthwashes.
Abstract
Analytical methods for detecting atranol, chloroatranol, evernic acid, (+)-usnic acid, and atranorin in sanitary napkins and mouthwashes were developed using ultrahigh performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS). UHPLC-MS/MS conditions were optimized for rapid, sensitive, and simultaneous analysis of the five allergenic compounds. The methods were validated by assessing their specificity, matrix effects, limit of detection (LOD), limit of quantification (LOQ), linearity, accuracy, and precision. Good linearity was achieved with a determination coefficient of ≥0.99. The LOD and LOQ were 2.1-9.8 and 6.4-29.6 ng/g for sanitary napkins and 0.29-0.48 and 0.87-1.45 ng/mL for mouthwashes, respectively. The accuracy and precision were within an acceptable range according to the criteria reported in the European SANTE/11813/2017 guidelines (70-120 % recovery, <20 % relative standard deviation). Therefore, these methods can be used to analyze atranol, chloroatranol, evernic acid, (+)-usnic acid, and atranorin in sanitary napkins and mouthwashes.
참고문헌 (27)
- S. J. Challacombe, , Br. Dent. J, 228(9), pp.656~657 (2020)
- A. Chopra, , Jpn. Dent. Sci. Rev, 57, pp.39~45 (2021)
- F. Carrouel, , J. Dent. Res, 100(2), pp.124~132 (2021)
- C. -J. Gao, , Environ. Sci. Technol, 54(2), pp.930~937 (2020)
- E. L. Eason, , Can. Med. Assoc. J, 154(8), pp.1173~1176 (1996)
- C. Foti, , Aust. J. Dermatol, 42(2), pp.145~ (2001)
- J. D. Williams, , Contact Derm, 56(3), pp.164~167 (2007)
- L. Wujanto, , Contact Derm, 66(3), pp.161~162 (2012)
- P. Romita, , Contact Derm, 82(3), pp.169~170 (2020)
- E. Gagari, , Oral. Surg. Oral. Med. Oral. Pathol. Oral. Radiol. Endod, 80(4), pp.432~439 (1995)
- M. Rademaker, , Aust. J. Dermatol, 45(4), pp.234~235 (2004)
- B. Desmedt, , Contact Derm, 82(5), pp.279~282 (2020)
- A. C. de Groot, , Contact Derm, 36(2), pp.57~86 (1997)
- "Regulation (EC) No 1223", 2009 of the European Parliament and of the Council of 30 November 2009 on cosmetic products, 2009
- D. Joulain, , Flavour Fragr. J, 24(2), pp.49~61 (2009)
- D. Joulain, , Flavour Fragr. J, 24(3), pp.105~116 (2009)
- J. D. Johansen, , Contact Derm, 54(4), pp.192~195 (2006)
- "LC-MS Quantification Method for Quantification of Atranol and Chloroatranol in Moss Extracts", The International Fragrance Association, ~ (2017)
- S. G. Musharraf, , J. Pharm. Biomed. Anal, 146, pp.279~284 (2017)
- J. -F. Goursot, , Flavour Fragr. J, 34(1), pp.28~35 (2019)
- R. Bossi, , J. Sep. Sci, 27(7-8), pp.537~540 (2004)
- S. C. Rastogi, , Contact Derm, 50(6), pp.367~370 (2004)
- R. D. Hiserodt, , J. Chromatogr. A, 888(1-2), pp.103~111 (2000)
- I. Ž. Stojanović, , J. Serb. Chem. Soc, 76(7), pp.987~994 (2011)
- M. López-Nogueroles, , Anal. Chim. Acta, 826, pp.28~34 (2014)
- Ministry of Food and Drug Safety, "Guideline 0213-01", ~ (2015)
- ICH Guideline, "Q2(R1): Validation of Analytical Procedures: Text and Methodology Q2(R1) in ICH Harmonised Tripartite Guideline", ~ (2005)