충청일부지역 자궁내막암 환자들의 암 단계에 미치는 영향 요인
Factors Influencing on Cancer Progression among Patients with Endometrial Cancer in Chungcheong Area
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본 연구는 충청일부지역 자궁내막암 환자들의 암 단계에 영향을 미치는 요인들을 규명하기 위해 수행하였다. 자료는 2016년 10월 17일부터 11월 30일까지 D와 K 지역에 소재한 종합병원에 내원한 환자 218명을 대상으로 설문 및 면접조사를 하였다. 연구방법은 일반적 특성은 실수와 백분율로 산출하였다. 자궁내막암 단계와 의료특성과 관련된 요인은 X2-test로 분석하였다. 자궁내막암 단계에 따른 영향을 규명하기 위해 다중 회귀분석(Multiple regression analysis)을 하였다. 도출된 연구결과는 다음과 같다. 첫째, 심리적 피곤을 많이 받은 경우가 진행 암 단계에서 60.5%로 상피내 암의 58.2% 보다 유의하게 높게 나타났다(X2=3.76, p<.05). 둘째, 자궁내막암의 연령과 체중은 음의 상관관계를 보였다(r=-0.21, p<0.05). 셋째, 연령이 암 진행정도를 23.1%, 체중이 7.4%, 심리적 피곤 5.8%, 고기류 섭취가 2.7%로 각각 설명하였다. 이들 네 변수가 자궁내막암 진행 정도의 37.1%로 설명하였다. 따라서 연구결과 자궁내막암의 발생을 예방하기 위해 건강상태의 의료적 특성에 초점을 둔 건강교육프로그램 개발이 필요하다고 본다.
Abstract
The study is to identify the factors influencing on cancer progression among patients with endometrial cancer in Chungcheon area . Data were surveyed using interview and questionnaires by 218 patients who had visited two general hospitals which was located in D and K area from October 17 to November 30, 2016. The progression of endometrial cancer and medical characteristics were analyzed by chi-square test. The results were as follows. Firstly, patients(60.5%) who had received many psychological fatigue for cancer progression were significantly higher than patients(58.2%) with localized cancer((X2=3.76, p<.05). Secondly, there was a significantly negative correlation between age and body weight(r=--0.21, p<.05). Thirdly, the age explained the progression of endometrial cancer(23.1%), body weight(7.4%), psychological fatigue(5.8%), meat intake(2.7%), respectively. These four variables explained the progression of endometrial cancer(37.1%). In order to prevent the incidence of endometrial cancer, it is needed to develop health education programs that focus on medical characteristics of health status.
참고문헌 (13)
- W. T. Creasman, "Carcinoma of the Corpus Uteri", J Epidemiol Biostat, 6, pp.47~86 (2001)
- A. Jemal, "Cancer Statics", CA Cancer J Clin, 61, pp.212~236 (2011)
- W. H. Gotlieb, "Outcome of Fertility Sparing Treatment with Progestins in Young Patients with Endometrial Cancer", Obstet Gynecol, 102, pp.215~218 (2003)
- Joshua P. Kesterson, "Fertility-sparing treatment of endometrial cancer: options, outcomes and pitfalls", Journal of Gynecologic Oncology, 23(2), pp.120~124 (2012), 대한부인종양학회
- M. K. Kim, "Combined Medroxyprogesterone Acetate", levonorgestrel-intrauterine System Treatment in Young Women with Early-stage Endometrial Cancer, 2013, pp.209, 23~25
- R. J. Kurman, "Blaustein’s Pathology of the Female Genital Tract" (2004), Springer Verlag
- C. L Trimble, "Concurrent Endometrial Carcinoma in Women with A Biopsy Diagnosis of Atypical Endometrial Hyperplasia : A Gynecologic Oncology Group Study", Cancer, 106, pp.812~819 (2006)
- P. Dong, "Emerging Therapeutic Biomarkers in Endometrial Cancer", Biomed res Int, 201, pp.2~4 (2013)
- R. Rey, "AMH", MIS : What We Know Already About the Gene, The Protein and Its Regulation, 2003, pp.211, 23~25
- T. Kaku, "Conservative Therapy for Adenocarcinoma and Atypical Endometrial Hyperplasia of the Endometrium in Young Women : Central Pathologic Review and Treatment Outcome", Cancer Lett, 167, pp.51~53 (2001)
- M. Imai, "Medroxyprogesterone Acetate Therapy for Patients with Adenocarcinoma of the Endometrium Who Wish to for Patients with Adenocarcinoma of the Endometrium Who Wish to Preserve the Uterus Usefulness and Limitations", Eur J Gynecol. Oncol, 22, pp.218~220 (2001)
- Y. B. Kim, "Progesterone Alone As Primary Treatment of Endometrial Carcinoma in Pre-Menopausal Women : Report of Seven Cases and Review of the Literature", Cancer, 79, pp.321~323 (2007)
- T. C. Randall, "Progestin Treatment of Atypical Hyperplasia and Well-differentiated Carcinoma of the Endometrium in Women Under Age 40", Obstet Gynecolo, 90, pp.434~440 (2007)