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논문KCI 등재

여성 강박장애의 임상적 특성과 치료 전략

Clinical Characteristics and Treatment Strategies in Female Patients with Obsessive-Compulsive Disorder

김찬형|홍현주
대한신경정신의학회 (Korean Neuropsychiatric Association)|2006.03|신경정신의학 (JOURNAL OF THE KOREAN NEUROPSYCHIATRIC ASSOCIATION)|제45권 제2호|pp. 93-99

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참고문헌

키워드

여성·강박장애·임상 양상·치료반응.Female· Obsesive-compulsive disorder· Clinical characteristics· Treatment response.
주제분류정신과학

초록

강박장애는 강박 사고와 강박행동을 특징으로 하며 예 전에는 매우 드문 질환으로 여겨져 왔으나 최근에는 평생 유병율이 3.3%까지 보고되는 비교적 흔한 질환으로 알려 져 있다.1) 최근 강박장애의 신경생물학적 기전 및 증상의 특징들에 대해서 많은 연구 결과들2-4)이 발표되면서 강박 장애는 동질적인(homogenous) 질환이라기 보다는 비동 질적인(heterogenous) 질환군이라는 견해가 분명해지고 있다.5,6) 성별에 따른 강박장애의 차이에 대한 이해를 통해 강박 장애를 보다 깊게 이해할 수 있을 것이다. 여성과 남성은 신체의 크기 및 모양뿐 아니라 뇌의 크기나 발달과정에 이 르기까지 다양한 차이가 존재한다. 이러한 성별에 따른 신 체생리학적인 차이로 인해 성별에 따라 서로 다른 특이적 인 질환이 발현될 수도 있으며, 각각의 임상 양상, 치료반 응, 예후 또한 다를 수 있다.7) 이 주제는 매우 흥미로운 부 분이긴 하나, 강박장애의 경우 최근에서야 남녀 성별에 따 른 질환의 특성을 규명하려는 시도들이 이루어지고 있다. 이에 본 논문에서는 성에 따른 강박장애의 임상양상 및 여러 생물학적인 특성, 특히 여성 강박장애의 임상적인 특 성과 치료적인 측면을 중심으로 고찰하고자 한다.

Abstract

This article reviews clinical characteristics, neurobiological aspects and treatment strategies in female patient with obsessivecompulsive disorder (OCD) compared to male. Female with OCD had a later age of onset and different patterns of OCD symptomatology and comorbidity. Female with OCD showed more favorable course and also reported more frequently stressful event in preceding OCD onset. The onset or worsening of OCD was related to female reproductive cycle events, especially at menarche and postpartum. There is a paucity of investigation regarding gender difference in treatment response in OCD. It has been suggested that gender may contribute to the clinical and biological heterogeneity of OCD and also sexually dimorphic pattern of genetic susceptibility to OCD may be present. (J Korean Neuropsychiatr Assoc 2006;45(2):93-99)

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관련 논문AI추천

강박장애의 임상적 특징과 충동성의 관련성김세주, 김찬형, 노대영대한신경정신의학회 · 신경정신의학2009 · 제48권 제5호강박장애 및 아임상형 강박장애의 평생 유병률과 병발성박수빈, 박종익, 배재남, 서동우, 이동우, 이동은, 이준영, 조맹제, 조성진, 함봉진, 홍진표대한불안의학회 · 대한불안의학회지2009 · 제5권 제1호강박증 환자의 인지행동치료 순응도에영향을 미치는 요인에 관한 연구권준수, 김성년, 김지선, 박혜연, 신민섭, 하태현대한신경정신의학회 · 신경정신의학2013 · 제52권 제6호강박장애에서 정서 이상의 의미김찬형, 노대영, 황성식대한불안의학회 · 대한불안의학회지2010 · 제6권 제1호절도광(Kleptomania)에 대한 고찰김정현, 성명제대한신경정신의학회 · 신경정신의학2011 · 제50권 제3호치료저항성 강박장애의 약물학적 치료 및 통합적 치료 모형의 제안권준수, 하태현대한신경정신의학회 · 신경정신의학2003 · 제42권 제3호

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