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혈중 CA125 농도의 증가 및 혈복강이 동반된Meigs씨 증후군

Meigs' syndrome associated with elevated serum CA 125 leveland hemoperitoneum

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초록

Meigs’ syndrome은 복수와 흉수를 동반한 난소 종양에서 이 종양을 제거함으로써 복수, 흉수가 소실되는 질환이다. 폐경된 여성에서 복수와 흉수가 동반된 충실성의 부속기 종양이 있고, CA125가 상승되어 있는 경우 악성 난소 종양을 생각할 수 있다. 아직까지 난소 섬유종의 파열에 의한 혈복강을 동반한 Meig씨 증후군은 보고된 적이 없다. 본원에서는 CA125가 증가되었으며, 혈복강을 동반한 좌측 난소 섬유종 파열에 의한 Meigs’ syndrome을 경험하였기에 보고하는 바이다.

Abstract

Meigs’ syndrome is characterized by the pleural effusion and ascites in patient with soild benign ovarian tumors and the resolution of the effusions after resection of the tumor. Elevated serum carbohydrate antigen 125 (CA125) levels in postmenopausal women with solid adnexal masses, ascites and pleural effusion are highly suggestive for malignant ovary tumor. As far as I know, Meigs’ syndrome with hemoperitoneum due to ruptured ovarian fibroma has not been reported yet. We present a case of Meigs’ syndrome associated with elevated serum CA125 and hemoperitoneum due to ruptured ovarian fibroma.

참고문헌 (13)

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  2. Meigs JV, "Fibroma of the ovary with ascites and hydrothorax with report of seven cases", pp.249~67
  3. Chen FC, "Meigs’ syndrome in association with a locally invasive adenocarcinoma of the fallopian tube", 65, pp.761~2 (1995)
  4. Beck RP, "Atypical fibroma and thecomas of the ovary", pp.228~32
  5. Beck RP, "Review of 1019 benign ovarian neoplasms", pp.479~91
  6. Hodgkinson CP, "Lymphangiogram of Meigs' syndrome", pp.477~81
  7. Barak V, "Vascular endothelial growth factor plasma levels correlate to the clinical picture in severe ovarian hyperstimulation syndrome", 67(2), pp.261~5 (1997)
  8. Anteby SO, "Markedly elevated levels of vascular endothelial growth factor and interleukin 6 in Meigs syndrome", 184(3), pp.354~5 (2001)
  9. Black WC, "Benign ovarian stromal tumors associated with free peritoneal fluid", pp.538~45
  10. Meigs JV, "A futher contribution to the syndrome of the ovary with fluid in the abdomen and chest"
  11. Agranoff D,, "Pleural effusion and a pelvic mass", 74(871), pp.265~7 (1998)
  12. Knapp RC, "CA125 antigen levels in obstetric and gynecologic patients", pp.703~7
  13. Timmerman D, "Meigs’ syndrome with elevated serum CA 125 levels two case reports and review of the literature", 59, pp.405~8 (1995)

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