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논문KCI 등재

허혈성주산기뇌졸중

Ischemic perinatal stroke

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참고문헌

키워드

주제분류산부인과학

초록

최근 아동기 때 발견되는 신경학적 이상의 주요한 원인으로 주산기허혈성뇌졸중이 주목 받고 있다. 신생아 시기의 동맥성 뇌졸중의 발생빈도는 성인의 그것과 유사할 정도로 높은 비율을 보이고 있다. 신생아 시기에는 발작이 흔한 증상이며, 아동기 시기에는 편측마비나 발작이 있는 경우 후향적 검사에 의해 진단되고 있다. 예후는 발생 정도, 위치 등에 따라 다양하게 나타난다. 원인, 병태생리, 치료, 예후 등 많은 분야에 있어 자세히 알려진 바가 없어, 이 질환에 대한 정의, 증상, 기전 등의 병태생리 및 예후에 대한 이해를 위해 문헌고찰을 하였다.

Abstract

Ischemic perinatal stroke occurring around the time of delivery is increasingly recognized as a cause of neurological disability in children. Surprisingly, the incidence of arterial infarction in neonates is as high as the annual incidence of large-vessel ischemic stroke in adults. Neonatal seizure is the most common clinical finding that triggers assessment. In other children, ischemic perinatal stroke is recognized only retrospectively with emerging hemiparesis or seizures after the early months of life. The outcome of ischemic perinatal stroke is variable and depends on severity, anatomic localization and other factors not yet well characterized. There is much to be learned about the natural history of ischemic perinatal stroke and there is as yet no evidence-based strategy for prevention or treatment. The incidence, clinical presentation, pathogenesis, risk factors and outcomes of this disorder are reviewed.

참고문헌 (64)

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