A case of endometrial glassy cell carcinoma: a rare entity which necessitates of better understanding
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Endometrial glassy cell carcinoma (EGCC) is a rare neoplasm, accounting for 0.5% of the carcinomas in theendometrium, composed of cells with granular eosinophilic or amphophilic cytoplasm, giving it a ground glassappearance. Till date, only 14 cases of this carcinoma have been reported. In this report, we have described a caseof EGCC to help define standard diagnostic criteria and better understand the course, ideal treatment, and accurateprognosis of this disease. We report a case of a 64-year-old woman diagnosed with EGCC after an abnormal papsmear. She underwent a hysteroscopy, which led to the histological diagnosis. Laparotomic total hysterectomy andbilateral salpingo-oophorectomy were performed with pelvic lymphadenectomy and peritoneal and omental biopsies. Final pathological examination confirmed the initial diagnosis. Pelvic nodes removed during surgery and peritonealand omental biopsies were negative for tumor cells. Treatment was considered appropriate and the patient did notrequire additional therapies. She was subsequently assigned to clinical follow-up and is alive, with no evidence of thedisease.
Abstract
Endometrial glassy cell carcinoma (EGCC) is a rare neoplasm, accounting for 0.5% of the carcinomas in theendometrium, composed of cells with granular eosinophilic or amphophilic cytoplasm, giving it a ground glassappearance. Till date, only 14 cases of this carcinoma have been reported. In this report, we have described a caseof EGCC to help define standard diagnostic criteria and better understand the course, ideal treatment, and accurateprognosis of this disease. We report a case of a 64-year-old woman diagnosed with EGCC after an abnormal papsmear. She underwent a hysteroscopy, which led to the histological diagnosis. Laparotomic total hysterectomy andbilateral salpingo-oophorectomy were performed with pelvic lymphadenectomy and peritoneal and omental biopsies. Final pathological examination confirmed the initial diagnosis. Pelvic nodes removed during surgery and peritonealand omental biopsies were negative for tumor cells. Treatment was considered appropriate and the patient did notrequire additional therapies. She was subsequently assigned to clinical follow-up and is alive, with no evidence of thedisease.
참고문헌 (15)
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