A rare case of gastric-type mucinous adenocarcinoma in a woman with Peutz-Jeghers syndrome
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Adenocarcinoma of the cervix is less common than squamous cell carcinoma. Minimal deviation adenocarcinoma(adenoma malignum) is considered an extremely well-differentiated variant of GAS. An association exists betweenGAS and Peutz-Jeghers syndrome, which is a rare autosomal dominant disorder characterized by mucocutaneouspigmentation and multiple hamartomatous polyps in the gastrointestinal tracts. The incidence of GAS in patients withPeutz-Jeghers syndrome is estimated to be 11–17%. We present a rare case of adenoma malignum, diagnosed usingcolposcopic biopsy in a woman with Peutz-Jeghers syndrome, which was histopathologically confirmed to be GASafter surgery.
Abstract
Adenocarcinoma of the cervix is less common than squamous cell carcinoma. Minimal deviation adenocarcinoma(adenoma malignum) is considered an extremely well-differentiated variant of GAS. An association exists betweenGAS and Peutz-Jeghers syndrome, which is a rare autosomal dominant disorder characterized by mucocutaneouspigmentation and multiple hamartomatous polyps in the gastrointestinal tracts. The incidence of GAS in patients withPeutz-Jeghers syndrome is estimated to be 11–17%. We present a rare case of adenoma malignum, diagnosed usingcolposcopic biopsy in a woman with Peutz-Jeghers syndrome, which was histopathologically confirmed to be GASafter surgery.
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