Indocyanine green fluorescent image-guided inguinal sentinel lymph node biopsy in vulvar cancer
1
조회
0
다운로드
2
인용
0
참고문헌
키워드
초록
Objective: To demonstrate near-infrared fluorescence image-guided inguinal sentinel lymph node (SLN) biopsy in patients with vulvar cancer. Methods: A 40-year-old woman with a 3-cm-sized palpable left vulvar mass was diagnosed with vulvar cancer on biopsy with protrusion into the vaginal cavity. Pelvic contrast-enhanced magnetic resonance imaging and F-18 fluorodeoxyglucose positron-emission tomography-computed tomography showed a small ulcerative enhancing lesion confined to the left vulva without distant metastasis. The patient was scheduled for radical vulvectomy with a left inguinal SLN biopsy. Indocyanine green was injected directly into the vulvar mass to map lymphatic drainage. A 4-cm-sized linear incision was made on the left inguinal crease, and the lymphatic channels of the left inguinal area were dissected under fluorescent image guidance using a 1588 Advanced Imaging Modalities Platform laparoscopic camera (Stryker, Kalamazoo, MI, USA). Results: Fluorescence image-guided left inguinal SLN biopsy and radical vulvectomy were performed. The pathologic diagnosis confirmed vulvar adenoid cystic carcinoma with metastasis to the left inguinal lymph node (International Federation of Gynecology and Obstetrics stage IIIA). The patient was discharged without complications and received adjuvant radiotherapy. Conclusion: This video demonstrates a successful ICG fluorescence image-guided left inguinal SLN biopsy in a vulvar cancer patient using a laparoscopic camera. Mapping of inguinal SLNs in patients with vulvar cancer may help in retaining surgical radicality while minimizing operative complications.
Abstract
Objective: To demonstrate near-infrared fluorescence image-guided inguinal sentinel lymph node (SLN) biopsy in patients with vulvar cancer. Methods: A 40-year-old woman with a 3-cm-sized palpable left vulvar mass was diagnosed with vulvar cancer on biopsy with protrusion into the vaginal cavity. Pelvic contrast-enhanced magnetic resonance imaging and F-18 fluorodeoxyglucose positron-emission tomography-computed tomography showed a small ulcerative enhancing lesion confined to the left vulva without distant metastasis. The patient was scheduled for radical vulvectomy with a left inguinal SLN biopsy. Indocyanine green was injected directly into the vulvar mass to map lymphatic drainage. A 4-cm-sized linear incision was made on the left inguinal crease, and the lymphatic channels of the left inguinal area were dissected under fluorescent image guidance using a 1588 Advanced Imaging Modalities Platform laparoscopic camera (Stryker, Kalamazoo, MI, USA). Results: Fluorescence image-guided left inguinal SLN biopsy and radical vulvectomy were performed. The pathologic diagnosis confirmed vulvar adenoid cystic carcinoma with metastasis to the left inguinal lymph node (International Federation of Gynecology and Obstetrics stage IIIA). The patient was discharged without complications and received adjuvant radiotherapy. Conclusion: This video demonstrates a successful ICG fluorescence image-guided left inguinal SLN biopsy in a vulvar cancer patient using a laparoscopic camera. Mapping of inguinal SLNs in patients with vulvar cancer may help in retaining surgical radicality while minimizing operative complications.
참고문헌 (11)
- Burger MP, "The importance of the groin node status for the survival of T1 and T2 vulval carcinoma patients", Gynecol Oncol, 57, pp.327~334 (1995)
- Hinten F, "Risk factors for shortand long-term complications after groin surgery in vulvar cancer", Br J Cancer, 105, pp.1279~1287 (2011)
- Erickson BK, "Cost-effectiveness analysis of sentinel lymph node biopsy in the treatment of early-stage vulvar cancer", Int J Gynecol Cancer, 24, pp.1480~1485 (2014)
- Te Grootenhuis NC, "Sentinel nodes in vulvar cancer : long-term follow-up of the GROningen international study on sentinel nodes in vulvar cancer(GROINSS-V)I", Gynecol Oncol, 140, pp.8~14 (2016)
- Frumovitz M, "Near-infrared fluorescence for detection of sentinel lymph nodes in women with cervical and uterine cancers(FILM) : a randomised, phase 3, multicentre, non-inferiority trial", Lancet Oncol, 19, pp.1394~1403 (2018)
- Buda A, "Impact of indocyanine green for sentinel lymph node mapping in early stage endometrial and cervical cancer : comparison with conventional radiotracer(99m)Tc and", or blue dye, 2016, pp.23, 2183~2191
- Koual M, "Diagnostic value of indocyanine green fluorescence guided sentinel lymph node biopsy in vulvar cancer : a systematic review", Gynecol Oncol, 161, pp.436~441 (2021)
- Siegenthaler F, "Exploratory study of the clinical value of near-infrared sentinel lymph node mapping with indocyanine green in vulvar cancer patients", Front Oncol, 11, pp.652458~ (2021)
- Covens A, "Sentinel lymph node biopsy in vulvar cancer : systematic review, meta-analysis and guideline recommendations", Gynecol Oncol, 137, pp.351~361 (2015)
- Cihan Comba, "Videoendoscopic sentinel lymph node detection with icg and bilateral inguinofemoral lymphadenectomy in vulvar cancer comba-ozdemir technique", Obstetrics & Gynecology Science, 64(6), pp.552~554 (2021), 대한산부인과학회
- Gu H, "Longterm outcomes of individualized management after sentinel lymph-node biopsy for vulvar cancer", Int J Clin Oncol, 26, pp.784~793 (2021)