Precursor Lesions of Pancreatic Cancer

참고문헌 (119)

1. Isaji S, "Classification of pancreatic cancer: comparison of Japanese and UICC classifications", Pancreas, 28, pp.231~234 (2004)
2. Hruban RH, "Pancreatic intraepithelial neoplasia: a new nomenclature and classification system for pancreatic duct lesions", Am J Surg Pathol, 25, pp.579~586 (2001)
3. Klöppel G, "Tumours of the exocrine pancreas, In Pathology and genetics of tumours of the digestive system, World Health Organization Classification of Tumours", pp.219~240 (2000), IARC Press
4. Hruban RJ, "Tumors of the pancreas. AFIP Atlas of tumor pathology, Fourth series" (2007), American Registry of Pathology
5. Osako M, "Immunohistochemical study of mucin carbohydrates and core proteins in human pancreatic tumors", Cancer, 71, pp.2191~2199 (1993)
6. Nakamura A, "New classification of pancreatic intraductal papillary-mucinous tumour by mucin expression: its relationship with potential for malignancy", J Pathol, 197, pp.201~210 (2002)
7. Horinouchi M, "Expression of different glycoforms of membrane mucin (MUC1) and secretory mucin (MUC2, MUC5AC and MUC6) in pancreatic neoplasms", Acta Histochem Cytochem, 36, pp.443~453 (2003)
8. Yonezawa S, "Gene expression of gastric type mucin (MUC5AC) in pancreatic tumors: its relationship with the biological behavior of the tumor", Pathol Int, 49, pp.45~54 (1999)
9. Adsay NV, "Klimstra DS. Intraductal oncocytic papillary neoplasms of the pancreas", Am J Surg Pathol, 20, pp.980~994 (1996)
10. Furukawa T, "Classification of types of intraductal papillary-mucinous neoplasm of the pancreas: a consensus study", Virchows Arch, 447, pp.794~799 (2005)
11. Adsay NV, "Pathologically and biologically distinct types of epithelium in intraductal papillary mucinous neoplasms: delineation of an "intestinal" pathway of carcinogenesis in the pancreas", Am J Surg Pathol, 28, pp.839~848 (2004)
12. Almoguera C, "Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes", Cell, 53, pp.549~554 (1988)
13. Smit VT, "KRAS codon 12 mutations occur very frequently in pancreatic adenocarcinomas", Nucleic Acids Res, 16, pp.7773~7782 (1988)
14. Hruban RH, "Genetic progression in the pancreatic ducts", Am J Pathol, 156, pp.1821~1825 (2000)
15. Bos JL, "ras oncogenes in human cancer: a review", Cancer Res, 49, pp.4682~4689 (1989)
16. Pellegata NS, "K-ras and p53 gene mutations in pancreatic cancer: ductal and nonductal tumors progress through different genetic lesions", Cancer Res, 54, pp.1556~1560 (1994)
17. Yanagisawa A, "Frequent c-Kiras oncogene activation in mucous cell hyperplasias of pancreas suffering from chronic inflammation", Cancer Res, 53, pp.953~956 (1993)
18. Caldas C, "Detection of K-ras mutations in the stool of patients with pancreatic adenocarcinoma and pancreatic ductal hyperplasia", Cancer Res, 54, pp.3568~3573 (1994)
19. Day JD, "Immunohistochemical evaluation of HER-2", neu expression in pancreatic adenocarcinoma and pancreatic intraepithelial neoplasms, 1996, pp.27, 119~124
20. Rozenblum E, "Tumor-suppressive pathways in pancreatic carcinoma", Cancer Res, 57, pp.1731~1734 (1997)
21. Wilentz RE, "Inactivation of the p16 (INK4A) tumor-suppressor gene in pancreatic duct lesions: loss of intranuclear expression", Cancer Res, 58, pp.4740~4744 (1998)
22. DiGiuseppe JA, "Overexpression of p53 protein in adenocarcinoma of the pancreas", Am J Clin Pathol, 101, pp.684~688 (1994)
23. Hahn SA, "DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1", Science, 271, pp.350~353 (1996)
24. Wilentz RE, "Immunohistochemical labeling for dpc4 mirrors genetic status in pancreatic adenocarcinomas: a new marker of DPC4 inactivation", Am J Pathol, 156, pp.37~43 (2000)
25. Wilentz RE, "Loss of expression of Dpc4 in pancreatic intraepithelial neoplasia: evidence that DPC4 inactivation occurs late in neoplastic progression", Cancer Res, 60, pp.2002~2006 (2000)
26. McCarthy DM, "Pancreatic intraepithelial neoplasia and infiltrating adenocarcinoma: analysis of progression and recurrence by DPC4 immunohistochemical labeling", Hum Pathol, 32, pp.638~642 (2001)
27. Goggins M, "BRCA2 is inactivated late in the development of pancreatic intraepithelial neoplasia: evidence and implications", Am J Pathol, 156, pp.1767~1771 (2000)
28. Yamano M, "Genetic progression and divergence in pancreatic carcinoma", Am J Pathol, 156, pp.2123~2133 (2000)
29. Kimura M, "Detailed deletion mapping on chromosome arm 12q in human pancreatic adenocarcinoma: identification of a I-cM region of common allelic loss", Genes Chromosomes Cancer, 17, pp.88~93 (1996)
30. Yatsuoka T, "Association of poor prognosis with loss of 12q, 17p, and 18q, and concordant loss of 6q", 17p and 12q, Am J Gastroenterol, pp.2000, 95[DOI]
31. Fukushige S, "Frequent gain of copy number on the long arm of chromosome 20 in human pancreatic adenocarcinoma", Genes Chromosomes Cancer, 19, pp.161~169 (1997)
32. Fukushige S, "Loss of chromosome 18q is an early event in pancreatic ductal tumorigenesis", Cancer Res, 58, pp.4222~4226 (1998)
33. Matsubayashi H, "Methylation of cyclin D2 is observed frequently in pancreatic cancer but is also an age-related phenomenon in gastrointestinal tissues", Clin Cancer Res, 9, pp.1446~1452 (2003)
34. Sato N, "Discovery of novel targets for aberrant methylation in pancreatic carcinoma using high-throughput microarrays", Cancer Res, 63, pp.3735~3742 (2003)
35. Ueki T, "Identification and characterization of differentially methylated CpG islands in pancreatic carcinoma", Cancer Res, 61, pp.8540~8546 (2001)
36. Ueki T, "Hypermethylation of multiple genes in pancreatic adenocarcinoma", Cancer Res, 60, pp.1835~1839 (2000)
37. Fukushima N, "Aberrant methylation of preproenkephalin and p16 genes in pancreatic intraepithelial neoplasia and pancreatic ductal adenocarcinoma", Am J Pathol, 160, pp.1573~1581 (2002)
38. Fukushima N, "Diagnosing pancreatic cancer using methylation specific PCR analysis of pancreatic juice", Cancer Biol Ther, 2, pp.78~83 (2003)
39. Yamada N, "MUC1 expression is regulated by DNA methylation and histone H3 lysine 9 modification in cancer cells", Cancer Res, 68, pp.2708~2716 (2008)
40. Hamada T, "Mapping of the methylation pattern of the MUC2 promoter in pancreatic cancer cell lines, using bisulfite genomic sequencing", Cancer Lett, 227, pp.175~184 (2005)
41. Yamada N, "MUC2 expression is regulated by histone H3 modification and DNA methylation in pancreatic cancer", Int J Cancer, 119, pp.1850~1857 (2006)
42. Logsdon CD, "Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer", Cancer Res, 63, pp.2649~2657 (2003)
43. Flejou JF, "p53 protein expression and DNA ploidy in cystic tumors of the pancreas", Pancreas, 13, pp.247~252 (1996)
44. Sessa F, "Intraductal papillary- mucinous tumours represent a distinct group of pancreatic neoplasms: an investigation of tumour cell differentiation and K-ras, p53 and c-erbB-2 abnormalities in 26 patients", Virchows Arch, 425, pp.357~367 (1994)
45. Hoshi T, "Frequent K-ras mutations and absence of p53 mutations in mucin-producing tumors of the pancreas", J Surg Oncol, 55, pp.84~91 (1994)
46. Yoshizawa K, "Clonality and K-ras mutation analyses of epithelia in intraductal papillary mucinous tumor and mucinous cystic tumor of the pancreas", Virchows Arch, 441, pp.437~443 (2002)
47. Z'Graggen K, "Prevalence of activating K-ras mutations in the evolutionary stages of neoplasia in intraductal papillary mucinous tumors of the pancreas", Ann Surg, 226, pp.491~498 (1997)
48. Moore PS, "Pancreatic tumours: molecular pathways implicated in ductal cancer are involved in ampullary but not in exocrine nonductal or endocrine tumorigenesis", Br J Cancer, 84, pp.253~262 (2001)
49. Fujii H, "Genetic progression and heterogeneity in intraductal papillary-mucinous neoplasms of the pancreas", Am J Pathol, 151, pp.1447~1454 (1997)
50. Biankin AV, "Aberrant p16 (INK4A) and DPC4", Smad4 expression in intraductal papillary mucinous tumours of the pancreas is associated with invasive ductal adenocarcinoma, 2002, pp.50, 861~868
51. Nakata B, "Very low incidence of microsatellite instability in intraductal papillary- mucinous neoplasm of the pancreas", Int J Cancer, 102, pp.655~659 (2002)
52. Sasaki S, "Differential roles of alterations of p53, p16, and SMAD4 expression in the progression of intraductal papillary-mucinous tumors of the pancreas", Oncol Rep, 10, pp.21~25 (2003)
53. Satoh K, "K-ras mutation and p53 protein accumulation in intraductal mucin-hypersecreting neoplasms of the pancreas", Pancreas, 12, pp.362~368 (1996)
54. Iacobuzio-Donahue CA, "Dpc-4 protein is expressed in virtually all human intraductal papillary mucinous neoplasms of the pancreas: comparison with conventional ductal adenocarcinomas", Am J Pathol, 157, pp.755~761 (2000)
55. Su GH, "Germline and somatic mutations of the STK11", LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers, 1999, pp.154, 1835~1840
56. Sato N, "STK11", LKB1 Peutz- Jeghers gene inactivation in intraductal papillary-mucinous neoplasms of the pancreas, 2001, pp.159, 2017~2022
57. Maire F, "Intraductal papillary and mucinous pancreatic tumour: a new extracolonic tumour in familial adenomatous polyposis", Gut, 51, pp.446~449 (2002)
58. Chetty R, "Expression of Wnt-signaling pathway proteins in intraductal papillary mucinous neoplasms of the pancreas: a tissue microarray analysis", Hum Pathol, 37, pp.212~217 (2006)
59. Wada K., "p16 and p53 gene alterations and accumulations in the malignant evolution of intraductal papillary-mucinous tumors of the pancreas", J Hepatobiliary Pancreat Surg, 9, pp.76~85 (2002)
60. Sato N, "Aberrant methylation of CpG islands in intraductal papillary mucinous neoplasms of the pancreas", Gastroenterology, 123, pp.365~372 (2002)
61. Fukushima N, "Aberrant methylation of suppressor of cytokine signalling-1 (SOCS-1) gene in pancreatic ductal neoplasms", Br J Cancer, 89, pp.338~343 (2003)
62. House MG, "Molecular progression of promoter methylation in intraductal papillary mucinous neoplasms (IPMN) of the pancreas", Carcinogenesis, 24, pp.193~198 (2003)
63. Sato N, "Gene expression profiling identifies genes associated with invasive intraductal papillary mucinous neoplasms of the pancreas", Am J Pathol, 164, pp.903~914 (2004)
64. Terris B, "Characterization of gene expression profiles in intraductal papillary- mucinous tumors of the pancreas", Am J Pathol, 160, pp.1745~1754 (2002)
65. Bartsch D, "K-ras oncogene mutations indicate malignancy in cystic tumors of the pancreas", Ann Surg, 228, pp.79~86 (1998)
66. Brenin DR, "neoplasms of the pancreas. A clinicopathologic study, including DNA flow cytometry", Arch Surg, 130, pp.1048~1054 (1995)
67. Jimenez RE, "Sequential accumulation of K-ras mutations and p53 overexpression in the progression of pancreatic mucinous cystic neoplasms to malignancy", Ann Surg, 230, pp.501~509 (1999)
68. Kim SG, "Comparison of epigenetic and genetic alterations in mucinous cystic neoplasm and serous microcystic adenoma of pancreas", Mod Pathol, 16, pp.1086~1094 (2003)
69. Luttges J, "mucin profile of noninvasive and invasive mucinous cystic neoplasms of the pancreas", Am J Surg Pathol, 26, pp.466~471 (2002)
70. Zamboni G, "Mucinous cystic tumors of the pancreas: clinicopathological features, prognosis, and relationship to other mucinous cystic tumors", Am J Surg Pathol, 23, pp.410~422 (1999)
71. Iacobuzio-Donahue CA, "Dpc4 protein in mucinous cystic neoplasms of the pancreas: frequent loss of expression in invasive carcinomas suggests a role in genetic progression", Am J Surg Pathol, 24, pp.1544~1548 (2000)
72. Hollingsworth MA, "Mucins in cancer: protection and control of the cell surface", Nat Rev Cancer, 4, pp.45~60 (2004)
73. Lehmann JM, "MUC18, a marker of tumor progression in human melanoma, shows sequence similarity to the neural cell adhesion molecules of the immunoglobulin superfamily", Proc Natl Acad Sci U S A, 86, pp.9891~9895 (1989)
74. Chen Y, "Genome-wide search and identification of a novel gel-forming mucin MUC19", MUC19 in glandular tissues, 2004, pp.30, 155~165
75. Higuchi T, "Molecular cloning, genomic structure, and expression analysis of MUC20, a novel mucin protein, up-regulated in injured kidney", J Biol Chem, 279, pp.1968~1979 (2004)
76. Moniaux N, "Structural organization and classification of the human mucin genes", Front Biosci, 6, pp.D1192~D1206 (2001)
77. Kitamura H, "Expression of mucin carbohydrates and core proteins in carcinomas of the ampulla of Vater: their relationship to prognosis", Jpn J Cancer Res, 87, pp.631~640 (1996)
78. Utsunomiya T, "Expression of MUC1 and MUC2 mucins in gastric carcinomas: its relationship with the prognosis of the patients", Clin Cancer Res, 4, pp.2605~2614 (1998)
79. Sagara M, "Expression of mucin 1 (MUC1) in esophageal squamous-cell carcinoma: its relationship with prognosis", Int J Cancer, 84, pp.251~257 (1999)
80. Takao S, "Mucin core protein expression in extrahepatic bile duct carcinoma is associated with metastases to the liver and poor prognosis", Cancer, 86, pp.1966~1975 (1999)
81. Higashi M, "Expression of MUC1 and MUC2 mucin antigens in intrahepatic bile duct tumors: its relationship with a new morphological classification of cholangiocarcinoma", Hepatology, 30, pp.1347~1355 (1999)
82. Tamada S, "Expression of MUC1 and MUC2 mucins in extrahepatic bile duct carcinomas: its relationship with tumor progression and prognosis", Pathol Int, 52, pp.713~723 (2002)
83. Yonezawa S, "The expression of several types of mucin is related to the biological behavior of pancreatic neoplasms", J Hepatobiliary Pancreat Surg, 9, pp.328~341 (2002)
84. Hinoda Y, "Increased expression of MUC1 in advanced pancreatic cancer", J Gastroenterol, 38, pp.1162~1166 (2003)
85. Tsutsumida H, "Combined status of MUC1 mucin and surfactant apoprotein A expression can predict the outcome of patients with small-size lung adenocarcinoma", Histopathology, 44, pp.147~155 (2004)
86. Hamada T, "Mucin expression in pleomorphic adenoma of salivary gland: a potential role for MUC1 as a marker to predict recurrence", J Clin Pathol, 57, pp.813~821 (2004)
87. Yonezawa S, "Expression of mucin antigens in human cancers and its relationship with malignancy potential", Pathol Int, 47, pp.813~830 (1997)
88. Yamashita K, "Immunohistochemical study of mucin carbohydrates and core proteins in hepatolithiasis and cholangiocarcinoma", Int J Cancer, 55, pp.82~91 (1993)
89. Yonezawa S, "Expression of MUC2 gene product in mucinous carcinoma of the breast: Comparison with invasive ductal carcinoma", Acta Histochem Cytochem, 28, pp.239~246 (1995)
90. Yonezawa S, "MUC2 gene expression is found in noninvasive tumors but not in invasive tumors of the pancreas and liver: its close relationship with prognosis of the patients", Hum Pathol, 28, pp.344~352 (1997)
91. Matsukita S, "Expression of mucins (MUC1, MUC2, MUC5AC and MUC6) in mucinous carcinoma of the breast: comparison with invasive ductal carcinoma", Histopathology, 42, pp.26~36 (2003)
92. Yonezawa S, "Glycoconjugate with Ulex europaeus agglutinin-I-binding sites in normal mucosa, adenoma, and carcinoma of the human large bowel", J Natl Cancer Inst, 69, pp.777~785 (1982)
93. Sato E, "Blood group H(O) antigen in normal, dysplastic and carcinomatous esophageal epithelium", Gann, 75, pp.223~229 (1984)
94. Shimizu T, "Expression of Lewis X-related antigens in adenocarcinomas of lung", Histopathology, 22, pp.549~555 (1993)
95. Yonezawa S, "Sialosyl-Tn antigen. Its distribution in normal human tissues and expression in adenocarcinomas", Am J Clin Pathol, 98, pp.167~174 (1992)
96. Yonezawa S, "Differential mucin gene expression in human pancreatic and colon cancer cells", Biochem J, 276(Pt3), pp.599~605 (1991)
97. Burchell J, "Development and characterization of breast cancer reactive monoclonal antibodies directed to the core protein of the human milk mucin", Cancer Res, 47, pp.5476~5482 (1987)
98. Nakamori S, "MUC1 mucin expression as a marker of progression and metastasis of human colorectal carcinoma", Gastroenterology, 106, pp.353~361 (1994)
99. Saitou M, "MUC4 expression is a novel prognostic factor in patients with invasive ductal carcinoma of the pancreas", J Clin Pathol, 58, pp.845~852 (2005)
100. Swartz MJ, "MUC4 expression increases progressively in pancreatic intraepithelial neoplasia", Am J Clin Pathol, 117, pp.791~796 (2002)
101. Park HU, "Aberrant expression of MUC3 and MUC4 membrane-associated mucins and sialyl Le(x) antigen in pancreatic intraepithelial neoplasia", Pancreas, 26, pp.e48~e54 (2003)
102. Nagata K, "Analysis of mucins and CD10 expression in pancreatic intraductal neoplasia", Kagoshimadaigaku Igakuzashi, 57, pp.7~17 (2005)
103. Kim GE, "Aberrant expression of MUC5AC and MUC6 gastric mucins and sialyl Tn antigen in intraepithelial neoplasms of the pancreas", Gastroenterology, 123, pp.1052~1060 (2002)
104. Fukushima N, "Intraductal papillary tumors and mucinous cystic tumors of the pancreas: clinicopathologic study of 38 cases", Hum Pathol, 28, pp.1010~1017 (1997)
105. Adsay NV, "Intraductal papillary-mucinous neoplasms of the pancreas: an analysis of in situ and invasive carcinomas in 28 patients", Cancer, 94, pp.62~77 (2002)
106. Terris B, "Mucin gene expression in intraductal papillary-mucinous pancreatic tumours and related lesions", J Pathol, 197, pp.632~637 (2002)
107. Tanaka M, "International consensus guidelines for management of intraductal papillary mucinous neoplasms and mucinous cystic neoplasms of the pancreas", Pancreatology, 6, pp.17~32 (2006)
108. Adsay NV, "The dichotomy in the preinvasive neoplasia to invasive carcinoma sequence in the pancreas: differential expression of MUC1 and MUC2 supports the existence of two separate pathways of carcinogenesis", Mod Pathol, 15, pp.1087~1095 (2002)
109. Yonezawa S, "MUC-1 mucin expression in invasive areas of intraductal papillary mucinous tumors of the pancreas", Pathol Int, 48, pp.319~322 (1998)
110. Balague C, "In situ hybridization shows distinct patterns of mucin gene expression in normal, benign, and malignant pancreas tissues", Gastroenterology, 109, pp.953~964 (1995)
111. Gum JR Jr, "Mucin genes and the proteins they encode: structure, diversity, and regulation", Am J Respir Cell Mol Biol, 7, pp.557~564 (1992)
112. Gum JR Jr, "Molecular cloning of human intestinal mucin (MUC2) cDNA. Identification of the amino terminus and overall sequence similarity to prepro-von Willebrand factor", J Biol Chem, 269, pp.2440~2446 (1994)
113. Kim YS, "Diversity of mucin genes, structure, function, and expression", Gastroenterology, 109, pp.999~1001 (1995)
114. Pigny P, "Human mucin genes assigned to 11p15.5: identification and organization of a cluster of genes", Genomics, 38, pp.340~352 (1996)
115. De Bolos C, "MUC6 apomucin shows a distinct normal tissue distribution that correlates with Lewis antigen expression in the human stomach", Gastroenterology, 109, pp.723~734 (1995)
116. Ho SB, "Expression cloning of gastric mucin complementary DNA and localization of mucin gene expression", Gastroenterology, 109, pp.735~747 (1995)
117. Buisine MP, "Aberrant expression of a human mucin gene (MUC5AC) in rectosigmoid villous adenoma", Gastroenterology, 110, pp.84~91 (1996)
118. Ho JJ, "Methylation status of promoters and expression of MUC2 and MUC5AC mucins in pancreatic cancer cells", Int J Oncol, 22, pp.273~279 (2003)
119. Terada T, "Expression of MUC apomucins in normal pancreas and pancreatic tumours", J Pathol, 180, pp.160~165 (1996)

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