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Antireflux Surgery in Korea: A Nationwide Study from 2011 to 2014

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Background/Aims: Although laparoscopic fundoplication is a well-established therapy for gastroesophageal reflux disease (GERD) in Western countries, the mainstay of GERD treatment in Korea is long-term proton pump inhibitor (PPI) use. The aim of the present study was to evaluate nationwide data regarding antireflux surgery in Korea. Methods: Data from 2011 to 2014 were collected from the Korean Antireflux Surgery Study Group and then analyzed. Results: A total of 87 patients underwent laparoscopic fundoplication for the treatment of GERD. Preoperatively, typical symptoms were present in 81 patients (93%) and atypical symptoms were present in 51 patients (59%). Twenty-seven patients (31%) had poor PPI responses. The average surgical time and postoperative hospital stay were 116.3±42.3 minutes and 4.3±3.1 days, respectively. At 3 months after surgery, typical symptoms were completely controlled in 86.3% of patients and partially controlled in 11.7%, whereas atypical symptoms were completely controlled in 63.3% of patients and partially controlled in 23.3%. Conclusions: This study showed that although atypical symptoms and PPI nonresponders are common, the complete control rates of typical and atypical symptoms were 86.3% and 63.3%, respectively. Laparoscopic fundoplication is an efficacious method of controlling the symptoms of GERD and has an acceptable rate of postoperative morbidity and adverse symptoms.

Abstract

Background/Aims: Although laparoscopic fundoplication is a well-established therapy for gastroesophageal reflux disease (GERD) in Western countries, the mainstay of GERD treatment in Korea is long-term proton pump inhibitor (PPI) use. The aim of the present study was to evaluate nationwide data regarding antireflux surgery in Korea. Methods: Data from 2011 to 2014 were collected from the Korean Antireflux Surgery Study Group and then analyzed. Results: A total of 87 patients underwent laparoscopic fundoplication for the treatment of GERD. Preoperatively, typical symptoms were present in 81 patients (93%) and atypical symptoms were present in 51 patients (59%). Twenty-seven patients (31%) had poor PPI responses. The average surgical time and postoperative hospital stay were 116.3±42.3 minutes and 4.3±3.1 days, respectively. At 3 months after surgery, typical symptoms were completely controlled in 86.3% of patients and partially controlled in 11.7%, whereas atypical symptoms were completely controlled in 63.3% of patients and partially controlled in 23.3%. Conclusions: This study showed that although atypical symptoms and PPI nonresponders are common, the complete control rates of typical and atypical symptoms were 86.3% and 63.3%, respectively. Laparoscopic fundoplication is an efficacious method of controlling the symptoms of GERD and has an acceptable rate of postoperative morbidity and adverse symptoms.

참고문헌 (20)

  1. 정혜경, "Epidemiology of Gastroesophageal Reflux Disease in Asia: A Systematic Review", Journal of Neurogastroenterology and Motility (JNM), 17(1), pp.14~27 (2011), 대한소화기 기능성질환∙운동학회
  2. Kim KM, "Prevalence of gastroesophageal reflux disease in Korea and associated health-care utilization: a national population-based study", J Gastroenterol Hepatol, 27, pp.741~745 (2012)
  3. Becher A, "Systematic review: the association between symptomatic response to proton pump inhibitors and healthrelated quality of life in patients with gastro-oesophageal reflux disease", Aliment Pharmacol Ther, 34, pp.618~627 (2011)
  4. Fass R, "Systematic review: protonpump inhibitor failure in gastro-oesophageal reflux disease: where next?", Aliment Pharmacol Ther, 22, pp.79~94 (2005)
  5. Dallemagne B, "Laparoscopic Nissen fundoplication: preliminary report", Surg Laparosc Endosc, 1, pp.138~143 (1991)
  6. Lundell L, "Seven-year follow-up of a randomized clinical trial comparing proton-pump inhibition with surgical therapy for reflux oesophagitis", Br J Surg, 94, pp.198~203 (2007)
  7. Mahon D, "Randomized clinical trial of laparoscopic Nissen fundoplication compared with proton-pump inhibitors for treatment of chronic gastro-oesophageal reflux", Br J Surg, 92, pp.695~699 (2005)
  8. Parrilla P, "Long-term results of a randomized prospective study comparing medical and surgical treatment of Barrett’s esophagus", Ann Surg, 237, pp.291~298 (2003)
  9. Spechler SJ, "Long-term outcome of medical and surgical therapies for gastroesophageal reflux disease: followup of a randomized controlled trial", JAMA, 285, pp.2331~2338 (2001)
  10. Galmiche JP, "Laparoscopic antireflux surgery vs esomeprazole treatment for chronic GERD: the LOTUS randomized clinical trial", JAMA, 305, pp.1969~1977 (2011)
  11. Vakil N, "The Montreal definition and classification of gastroesophageal reflux disease: a global evidence-based consensus", Am J Gastroenterol, 101, pp.1900~1920 (2006)
  12. Viljakka M, "Incidence of antireflux surgery in Finland 1988-1993: influence of proton-pump inhibitors and laparoscopic technique", Scand J Gastroenterol, 32, pp.415~418 (1997)
  13. Stefanidis D, "Guidelines for surgical treatment of gastroesophageal reflux disease", Surg Endosc, 24, pp.2647~2669 (2010)
  14. Fernando HC, "Quality of life after antireflux surgery compared with nonoperative management for severe gastroesophageal reflux disease", J Am Coll Surg, 194, pp.23~27 (2002)
  15. 정혜경, "위식도역류질환 임상진료지침 개정안 2012", 대한소화기학회지, 60(4), pp.195~218 (2012), 대한소화기학회
  16. 이새별, "Early experiences of minimally invasive surgery to treat gastroesophageal reflux disease", 대한외과학회지, 84(6), pp.330~337 (2013), 대한외과학회
  17. 이상권, "Laparoscopic Nissen Fundoplication in Korean Patients with Gastroesophageal Reflux Disease", Yonsei Medical Journal, 50(1), pp.89~94 (2009), 연세대학교의과대학
  18. Campos GM, "Multivariate analysis of factors predicting outcome after laparoscopic Nissen fundoplication", J Gastrointest Surg, 3, pp.292~300 (1999)
  19. Auyang ED, "SAGES clinical spotlight review: endoluminal treatments for gastroesophageal reflux disease (GERD)", Surg Endosc, 27, pp.2658~2672 (2013)
  20. Liang WT, "Early and midterm outcome after laparoscopic fundoplication and a minimally invasive endoscopic procedure in patients with gastroesophageal reflux disease:a prospective observational study", J Laparoendosc Adv Surg Tech A, 25, pp.657~661 (2015)

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