Prevalence, Pathogenesis, Diagnosis, and Management of Microscopic Colitis
2
조회
0
다운로드
0
인용
0
참고문헌
키워드
초록
Microscopic colitis (MC), which is comprised of lymphocytic colitis and collagenous colitis, is a clinicopathological diagnosis that is commonly encountered in clinical practice during the evaluation and management of chronic diarrhea. With an incidence approaching the incidence of inflammatory bowel disease, physician awareness is necessary, as diagnostic delays result in a poor quality of life and increased health care costs. The physician faces multiple challenges in the diagnosis and management of MC, as these patients frequently relapse after successful treatment. This review article outlines the risk factors associated with MC, the clinical presentation, diagnosis and histologic findings, as well as a proposed treatment algorithm. Prospective studies are required to better understand the natural history and to develop validated histologic endpoints that may be used as end points in future clinical trials and serve to guide patient management.
Abstract
Microscopic colitis (MC), which is comprised of lymphocytic colitis and collagenous colitis, is a clinicopathological diagnosis that is commonly encountered in clinical practice during the evaluation and management of chronic diarrhea. With an incidence approaching the incidence of inflammatory bowel disease, physician awareness is necessary, as diagnostic delays result in a poor quality of life and increased health care costs. The physician faces multiple challenges in the diagnosis and management of MC, as these patients frequently relapse after successful treatment. This review article outlines the risk factors associated with MC, the clinical presentation, diagnosis and histologic findings, as well as a proposed treatment algorithm. Prospective studies are required to better understand the natural history and to develop validated histologic endpoints that may be used as end points in future clinical trials and serve to guide patient management.
참고문헌 (76)
- Munch A, "Microscopic colitis: clinical and pathologic perspectives", Clin Gastroenterol Hepatol, 13, pp.228~236 (2015)[DOI]
- Fernandez-Banares F, "Epidemiology of microscopic colitis", Gut, 56, pp.1033~ (2007)
- Gentile NM, "The epidemiology of microscopic colitis in Olmsted County from 2002 to 2010: a population-based study", Clin Gastroenterol Hepatol, 12, pp.838~842 (2014)[DOI]
- Pardi DS, "The epidemiology of microscopic colitis: a population based study in Olmsted County, Minnesota", Gut, 56, pp.504~508 (2007)[DOI]
- Bonderup OK, "The epidemiology of microscopic colitis: a 10-year pathologybased nationwide Danish cohort study", Scand J Gastroenterol, 50, pp.393~398 (2015)[DOI]
- Fernandez-Banares F, "Evolution of the incidence of collagenous colitis and lymphocytic colitis in Terrassa, Spain: a population-based study", Inflamm Bowel Dis, 17, pp.1015~1020 (2011)[DOI]
- Tong J, "Incidence, prevalence, and temporal trends of microscopic colitis: a systematic review and meta-analysis", Am J Gastroenterol, 110, pp.265~276 (2015)[DOI]
- Masclee GM, "Increased risk of microscopic colitis with use of proton pump inhibitors and non-steroidal anti-inflammatory drugs", Am J Gastroenterol, 110, pp.749~759 (2015)[DOI]
- Nielsen OH, "Microscopic colitis: a missed diagnosis", Lancet, 364, pp.2055~2057 (2004)[DOI]
- Beaugerie L, "Review article: drug-induced microscopic colitis-proposal for a scoring system and review of the literature", Aliment Pharmacol Ther, 22, pp.277~284 (2005)[DOI]
- Fernandez-Banares F, "Drug consumption and the risk of microscopic colitis", Am J Gastroenterol, 102, pp.324~330 (2007)[DOI]
- Bonderup OK, "Drug exposure and risk of microscopic colitis: a nationwide Danish case-control study with 5751 cases", Inflamm Bowel Dis, 20, pp.1702~1707 (2014)[DOI]
- Casella G, "Colonic left-side increase of eosinophils: a clue to drug-related colitis in adults", Aliment Pharmacol Ther, 29, pp.535~541 (2009)[DOI]
- Gleeson MH, "Non-steroidal anti-inflammatory drugs, aspirin and newly diagnosed colitis: a case-control study", Aliment Pharmacol Ther, 17, pp.817~825 (2003)[DOI]
- Levy AM, "Increased eosinophil infiltration and degranulation in colonic tissue from patients with collagenous colitis", Am J Gastroenterol, 96, pp.1522~1528 (2001)[DOI]
- Mahid SS, "Smoking and inflammatory bowel disease: a meta-analysis", Mayo Clin Proc, 81, pp.1462~1471 (2006)[DOI]
- Yen EF, "Current and past cigarette smoking significantly increase risk for microscopic colitis", Inflamm Bowel Dis, 18, pp.1835~1841 (2012)[DOI]
- Vigren L, "Is smoking a risk factor for collagenous colitis", Scand J Gastroenterol, 46, pp.1334~1339 (2011)[DOI]
- Munch A, "Microscopic colitis: current status, present and future challenges: statements of the European Microscopic Colitis group", J Crohns Colitis, 6, pp.932~945 (2012)[DOI]
- Pardi DS, "Microscopic colitis", Gastroenterology, 140, pp.1155~1165 (2011)[DOI]
- O'Toole A, "Optimal management of collagenous colitis: a review", Clin Exp Gastroenterol, 9, pp.31~39 (2016)
- Bjornbak C, "Microscopic colitis: clinical findings, topography and persistence of histopathological subgroups", Aliment Pharmacol Ther, 34, pp.1225~1234 (2011)[DOI]
- Storr MA, "Microscopic colitis: epidemiology, pathophysiology, diagnosis and current management-an update 2013", ISRN Gastroenterol, 2013, pp.352718~ (2013)
- Kamp EJ, "Irritable bowel syndrome and microscopic colitis: a systematic review and meta-analysis", Clin Gastroenterol Hepatol, 14, pp.659~668 (2016)[DOI]
- Abboud R, "Symptomatic overlap between microscopic colitis and irritable bowel syndrome: a prospective study", Inflamm Bowel Dis, 19, pp.550~553 (2013)[DOI]
- Macaigne G, "Microscopic colitis or functional bowel disease with diarrhea: a French prospective multicenter study", Am J Gastroenterol, 109, pp.1461~1470 (2014)[DOI]
- Hjortswang H, "Defining clinical criteria for clinical remission and disease activity in collagenous colitis", Inflamm Bowel Dis, 15, pp.1875~1881 (2009)[DOI]
- Cotter TG, "Development of a microscopic colitis disease activity index: a prospective cohort study", Gut, 67, pp.441~446 (2018)[DOI]
- Pisani LF, "Microscopic colitis: what do we know about pathogenesis", Inflamm Bowel Dis, 22, pp.450~458 (2016)[DOI]
- Bo-Linn GW, "An evaluation of the significance of microscopic colitis in patients with chronic diarrhea", J Clin Invest, 75, pp.1559~1569 (1985)[DOI]
- Burgel N, "Mechanisms of diarrhea in collagenous colitis", Gastroenterology, 123, pp.433~443 (2002)[DOI]
- Stampfl DA, "Collagenous colitis: pathophysiologic considerations", Dig Dis Sci, 36, pp.705~711 (1991)[DOI]
- Protic M, "Mechanism of diarrhea in microscopic colitis", World J Gastroenterol, 11, pp.5535~5539 (2005)[DOI]
- Bohr J, "Effect of fasting on diarrhoea in collagenous colitis", Digestion, 65, pp.30~34 (2002)[DOI]
- Lee E, "Subepithelial collagen table thickness in colon specimens from patients with microscopic colitis and collagenous colitis", Gastroenterology, 103, pp.1790~1796 (1992)[DOI]
- Ung KA, "Role of bile acids and bile acid binding agents in patients with collagenous colitis", Gut, 46, pp.170~175 (2000)[DOI]
- Zeroogian JM, "Collagenous colitis and lymphocytic colitis", Annu Rev Med, 45, pp.105~118 (1994)[DOI]
- Jarnerot G, "Faecal stream diversion in patients with collagenous colitis", Gut, 38, pp.154~155 (1996)
- Veress B, "Microscopic colitis syndrome", Gut, 36, pp.880~886 (1995)[DOI]
- Andresen L, "Activation of nuclear factor kappabeta in colonic mucosa from patients with collagenous and ulcerative colitis", Gut, 54, pp.503~509 (2005)[DOI]
- Bohr J, "Collagenous colitis: a retrospective study of clinical presentation and treatment in 163 patients", Gut, 39, pp.846~851 (1996)[DOI]
- Stewart M, "The association of coeliac disease and microscopic colitis: a large population-based study", Aliment Pharmacol Ther, 33, pp.1340~1349 (2011)[DOI]
- Green PH, "An association between microscopic colitis and celiac disease", Clin Gastroenterol Hepatol, 7, pp.1210~1216 (2009)[DOI]
- Park T, "Microscopic colitis: a review of etiology, treatment and refractory disease", World J Gastroenterol, 21, pp.8804~8810 (2015)[DOI]
- Koskela RM, "Human leucocyte antigen and TNFalpha polymorphism association in microscopic colitis", Eur J Gastroenterol Hepatol, 20, pp.276~282 (2008)[DOI]
- Fernandez-Banares F, "Predisposing HLADQ2 and HLA-DQ8 haplotypes of coeliac disease and associated enteropathy in microscopic colitis", Eur J Gastroenterol Hepatol, 17, pp.1333~1338 (2005)[DOI]
- Fine KD, "High prevalence of celiac spruelike HLA-DQ genes and enteropathy in patients with the microscopic colitis syndrome", Am J Gastroenterol, 95, pp.1974~1982 (2000)[DOI]
- Garner C, "Genome-wide association study of celiac disease in North America confirms FRMD4B as new celiac locus", PLoS One, 9, pp.e101428~ (2014)[DOI]
- ASGE Standards of Practice Committee, "Endoscopic mucosal tissue sampling", Gastrointest Endosc, 78, pp.216~224 (2013)[DOI]
- Langner C, "Histology of microscopic colitis-review with a practical approach for pathologists", Histopathology, 66, pp.613~626 (2015)[DOI]
- Fiehn AM, "Observer variability in the histopathologic diagnosis of microscopic colitis and subgroups", Hum Pathol, 44, pp.2461~2466 (2013)[DOI]
- Ayata G, "Prevalence and significance of inflammatory bowel disease-like morphologic features in collagenous and lymphocytic colitis", Am J Surg Pathol, 26, pp.1414~1423 (2002)[DOI]
- Mahajan D, "Lymphocytic colitis and collagenous colitis: a review of clinicopathologic features and immunologic abnormalities", Adv Anat Pathol, 19, pp.28~38 (2012)[DOI]
- Carmack SW, "Lymphocytic disorders of the gastrointestinal tract: a review for the practicing pathologist", Adv Anat Pathol, 16, pp.290~306 (2009)[DOI]
- Yen EF, "Review article: microscopic colitis--lymphocytic, collagenous and ‘mast cell' colitis", Aliment Pharmacol Ther, 34, pp.21~32 (2011)[DOI]
- Limsui D, "Observer variability in the histologic diagnosis of microscopic colitis", Inflamm Bowel Dis, 15, pp.35~38 (2009)[DOI]
- Bonderup OK, "Budesonide treatment of collagenous colitis: a randomised, double blind, placebo controlled trial with morphometric analysis", Gut, 52, pp.248~251 (2003)[DOI]
- Miehlke S, "Budesonide treatment for collagenous colitis: a randomized, double-blind, placebo-controlled, multicenter trial", Gastroenterology, 123, pp.978~984 (2002)[DOI]
- Yen EF, "Review of the microscopic colitides", Curr Gastroenterol Rep, 13, pp.458~464 (2011)[DOI]
- Bonderup OK, "Long-term budesonide treatment of collagenous colitis: a randomised, double-blind, placebo-controlled trial", Gut, 58, pp.68~72 (2009)[DOI]
- Miehlke S, "Oral budesonide for maintenance treatment of collagenous colitis: a randomized, doubleblind, placebo-controlled trial", Gastroenterology, 135, pp.1510~1516 (2008)[DOI]
- Hjortswang H, "Health-related quality of life is impaired in active collagenous colitis", Dig Liver Dis, 43, pp.102~109 (2011)[DOI]
- Madisch A, "Oral budesonide therapy improves quality of life in patients with collagenous colitis", Int J Colorectal Dis, 20, pp.312~316 (2005)[DOI]
- Munch A, "Low-dose budesonide for maintenance of clinical remission in collagenous colitis: a randomised, placebo-controlled, 12-month trial", Gut, 65, pp.47~56 (2016)[DOI]
- Yen EF, "Non-IBD colitides (eosinophilic, microscopic)", Best Pract Res Clin Gastroenterol, 26, pp.611~622 (2012)
- Amaro R, "Collagenous colitis treated successfully with bismuth subsalicylate", Dig Dis Sci, 45, pp.1447~1450 (2000)[DOI]
- Fine KD, "Efficacy of open-label bismuth subsalicylate for the treatment of microscopic colitis", Gastroenterology, 114, pp.29~36 (1998)[DOI]
- Olesen M, "Lymphocytic colitis: a retrospective clinical study of 199 Swedish patients", Gut, 53, pp.536~541 (2004)[DOI]
- Gentile NM, "Outcomes of patients with microscopic colitis treated with corticosteroids: a populationbased study", Am J Gastroenterol, 108, pp.256~259 (2013)[DOI]
- Miehlke S, "Long-term follow-up of collagenous colitis after induction of clinical remission with budesonide", Aliment Pharmacol Ther, 22, pp.1115~1119 (2005)[DOI]
- Stewart MJ, "Prednisolone and budesonide for short- and long-term treatment of microscopic colitis: systematic review and meta-analysis", Clin Gastroenterol Hepatol, 9, pp.881~890 (2011)[DOI]
- Pardi DS, "Lymphocytic colitis: clinical features, treatment, and outcomes", Am J Gastroenterol, 97, pp.2829~2833 (2002)[DOI]
- Pardi DS, "Treatment of refractory microscopic colitis with azathioprine and 6-mercaptopurine", Gastroenterology, 120, pp.1483~1484 (2001)[DOI]
- Riddell J, "Collagenous colitis: oral low-dose methotrexate for patients with difficult symptoms: long-term outcomes", J Gastroenterol Hepatol, 22, pp.1589~1593 (2007)[DOI]
- Munch A, "Lack of effect of methotrexate in budesonide-refractory collagenous colitis", Clin Exp Gastroenterol, 6, pp.149~152 (2013)
- Esteve M, "Efficacy of anti-TNF therapies in refractory severe microscopic colitis", J Crohns Colitis, 5, pp.612~618 (2011)[DOI]
