Prophylactic Pancreatic Stent Placement for Endoscopic Duodenal Ampullectomy: A Single-Center Retrospective Study
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Background/Aims: We investigated the efficacy of prophylacticpancreatic stent placement for preventing postprocedurepancreatitis in patients undergoing endoscopicpapillectomy. Methods: This retrospective study included82 consecutive patients who underwent endoscopic papillectomyfor benign ampullary neoplasm at Samsung MedicalCenter between August 2002 and June 2011. The patientswere subdivided into two groups, namely, those who receivedprophylactic pancreatic stent placement and those whodid not. Patient demographics, baseline blood test, tumorcharacteristics, and endoscopic treatment data were collected. The primary endpoint was postprocedure pancreatitis. Results: There was no difference in the development ofpostprocedure pancreatitis between the stent group and theno stent group (6/54, 10.5% and 2/28, 7.14%, respectively;p=1.00). At baseline, there were no significant differencesbetween the two groups in terms of their risk factors for pancreatitisexcept pancreatic duct dye injection. The stent groupwas more likely to have dye injection than the nonstent group(100% vs 42.8%, p<0.001). However, in a logistic regressionanalysis, no significant difference was observed in the riskfactors for pancreatitis including dye injection. Conclusions: Our data suggest that routine prophylactic pancreatic ductstent placement in all patients undergoing endoscopic papillectomymay not be necessary and that large-scale prospectivestudies are required to identify the subgroup of patientswho would benefit.
Abstract
Background/Aims: We investigated the efficacy of prophylacticpancreatic stent placement for preventing postprocedurepancreatitis in patients undergoing endoscopicpapillectomy. Methods: This retrospective study included82 consecutive patients who underwent endoscopic papillectomyfor benign ampullary neoplasm at Samsung MedicalCenter between August 2002 and June 2011. The patientswere subdivided into two groups, namely, those who receivedprophylactic pancreatic stent placement and those whodid not. Patient demographics, baseline blood test, tumorcharacteristics, and endoscopic treatment data were collected. The primary endpoint was postprocedure pancreatitis. Results: There was no difference in the development ofpostprocedure pancreatitis between the stent group and theno stent group (6/54, 10.5% and 2/28, 7.14%, respectively;p=1.00). At baseline, there were no significant differencesbetween the two groups in terms of their risk factors for pancreatitisexcept pancreatic duct dye injection. The stent groupwas more likely to have dye injection than the nonstent group(100% vs 42.8%, p<0.001). However, in a logistic regressionanalysis, no significant difference was observed in the riskfactors for pancreatitis including dye injection. Conclusions: Our data suggest that routine prophylactic pancreatic ductstent placement in all patients undergoing endoscopic papillectomymay not be necessary and that large-scale prospectivestudies are required to identify the subgroup of patientswho would benefit.
참고문헌 (29)
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