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Radiation Exposure from Abdominal Imaging Studies in Patients with Intestinal Behçet Disease

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Background/Aims: Recently, several studies have revealedthat diagnostic imaging can result in exposure to harmfullevels of ionizing radiation in inflammatory bowel disease patients. However, the extent of radiation exposure in intestinalBehçet disease (BD) patients has not been documented. Theaim of this study was to estimate the radiation exposure fromabdominal imaging studies in intestinal BD patients. Methods:Patients with a diagnosis of intestinal BD establishedbetween January 1990 and March 2012 were investigatedat a single tertiary academic medical center. The cumulativeeffective dose (CED) was calculated retrospectively fromstandard tables and by counting the number of abdominalimaging studies performed. High exposure was defined asCED >50 mSv. Results: In total, 270 patients were includedin the study. The mean CED was 41.3 mSv, and 28.1% ofpatients were exposed to high levels of radiation. Computedtomography (CT) accounted for 81.7% of the total effectivedose. In multivariate analyses, predictors of high radiationexposure were azathioprine/6-mercaptopurine use, surgery,and hospitalization. Conclusions: Approximately a quarterof intestinal BD patients were exposed to harmful levels ofdiagnostic radiation, mainly from CT examination. Cliniciansshould reduce the number of unnecessary CT examinationsand consider low-dose CT profiles or alternative modalitiessuch as magnetic resonance enterography.

Abstract

Background/Aims: Recently, several studies have revealedthat diagnostic imaging can result in exposure to harmfullevels of ionizing radiation in inflammatory bowel disease patients. However, the extent of radiation exposure in intestinalBehçet disease (BD) patients has not been documented. Theaim of this study was to estimate the radiation exposure fromabdominal imaging studies in intestinal BD patients. Methods:Patients with a diagnosis of intestinal BD establishedbetween January 1990 and March 2012 were investigatedat a single tertiary academic medical center. The cumulativeeffective dose (CED) was calculated retrospectively fromstandard tables and by counting the number of abdominalimaging studies performed. High exposure was defined asCED >50 mSv. Results: In total, 270 patients were includedin the study. The mean CED was 41.3 mSv, and 28.1% ofpatients were exposed to high levels of radiation. Computedtomography (CT) accounted for 81.7% of the total effectivedose. In multivariate analyses, predictors of high radiationexposure were azathioprine/6-mercaptopurine use, surgery,and hospitalization. Conclusions: Approximately a quarterof intestinal BD patients were exposed to harmful levels ofdiagnostic radiation, mainly from CT examination. Cliniciansshould reduce the number of unnecessary CT examinationsand consider low-dose CT profiles or alternative modalitiessuch as magnetic resonance enterography.

참고문헌 (38)

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