돌발성 난청 치료 한약 처방의 네트워크 분석
Network Analysis of Herbal Prescriptions for Sudden Sensorineural Hearing Loss
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Abstract Objectives : In this study, we conducted a network analysis of herbal prescriptions for Sudden Sensorineural Hearing Loss(SSNHL) used in Korean medicine clinical practice to explore the central herbs and herbal combinations that play a role in SSNHL, the groups of herbs that are closely connected and exhibit key efficacy within the prescriptions, and the prescriptions related to each group. Methods : We searched OASIS with the title SSNHL. The publication dates were 1965 to 2025, and a total of 12 papers were selected. Results : 1. The most frequent herb was Poria Sclerotium, which was used in 28 prescriptions. 2. The most frequent herb combination was Rehmanniae Radix-Poria Sclerotium, which was included in 32 prescriptions. 3. Poria Sclerotium showed the highest degree centrality at 6.1. 4. The results of the cohesion analysis were classified into two networks 5. Using the K-HERB NETWORK, prescriptions such as Yugmijihwang-tang, Palmijihwang-tang, Gamisoyo-san, and others were derived. Conclusions : This study is the first network analysis study on SSNHL, which increases understanding of herbal medicine prescriptions for SSNHL and provides objective basic data to help with clinical application or follow-up research.
Abstract
Abstract Objectives : In this study, we conducted a network analysis of herbal prescriptions for Sudden Sensorineural Hearing Loss(SSNHL) used in Korean medicine clinical practice to explore the central herbs and herbal combinations that play a role in SSNHL, the groups of herbs that are closely connected and exhibit key efficacy within the prescriptions, and the prescriptions related to each group. Methods : We searched OASIS with the title SSNHL. The publication dates were 1965 to 2025, and a total of 12 papers were selected. Results : 1. The most frequent herb was Poria Sclerotium, which was used in 28 prescriptions. 2. The most frequent herb combination was Rehmanniae Radix-Poria Sclerotium, which was included in 32 prescriptions. 3. Poria Sclerotium showed the highest degree centrality at 6.1. 4. The results of the cohesion analysis were classified into two networks 5. Using the K-HERB NETWORK, prescriptions such as Yugmijihwang-tang, Palmijihwang-tang, Gamisoyo-san, and others were derived. Conclusions : This study is the first network analysis study on SSNHL, which increases understanding of herbal medicine prescriptions for SSNHL and provides objective basic data to help with clinical application or follow-up research.