메니에르병에 대한 苓桂朮甘湯의 효과: 체계적 문헌고찰 및 메타분석
The Effect of Yeonggyechulgam-tang for Meniere’s Disease: A Systematic Review and Meta-Analysis
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Abstract Objectives : The purpose of this study is to assess the effect of using Yeonggyechulgam-tang(YGCGT) for meniere’s disease. Methods : We searched randomized controlled trials(RCTs) that used YGCGT for meniere’s disease in 10 databases(RISS, KISS, ScienceON, KCI, OASIS, DBpia, CNKI, Wanfang Database, PubMed, Cochrane Library) on May 26, 2025. Outcome measurements included total effective rate(TER) as the primary outcome measurements, and the secondary outcome measurements included TCM symptom score(TSS), SF-36(The medical outcome study 36-item short-form health survey), dizziness handicap inventory(DHI), blood rheological indexes, immunoglobulins and complement, T lymphocytes, PTA effective rate etc. The indicator of stability included adverse reactions. A meta-analysis was conducted according to TER, TSS, DHI. Results : A total of 7 randomized control trials were selected. The treatment group which used YGCGT showed significant improvement effects in TER and TSS(dizziness, hearing), DHI to the control group which used western medicine of chinese patent medicine alone. TER : (RR: 4.75, CI 2.29 to 9.83, P<0.0001), TSS(dizziness) : (MD : 1.38, CI : 1.19 to 1.57, P<0.00001), TSS(hearing) : (MD : 1.11, CI : 0.97 to 1.28, P<0.00001), DHI : (MD : -8.24, CI : -10.73 to –5.76, P<0.00001). Conclusion : This study suggests that YGCGT is effective for meniere’s disease.
Abstract
Abstract Objectives : The purpose of this study is to assess the effect of using Yeonggyechulgam-tang(YGCGT) for meniere’s disease. Methods : We searched randomized controlled trials(RCTs) that used YGCGT for meniere’s disease in 10 databases(RISS, KISS, ScienceON, KCI, OASIS, DBpia, CNKI, Wanfang Database, PubMed, Cochrane Library) on May 26, 2025. Outcome measurements included total effective rate(TER) as the primary outcome measurements, and the secondary outcome measurements included TCM symptom score(TSS), SF-36(The medical outcome study 36-item short-form health survey), dizziness handicap inventory(DHI), blood rheological indexes, immunoglobulins and complement, T lymphocytes, PTA effective rate etc. The indicator of stability included adverse reactions. A meta-analysis was conducted according to TER, TSS, DHI. Results : A total of 7 randomized control trials were selected. The treatment group which used YGCGT showed significant improvement effects in TER and TSS(dizziness, hearing), DHI to the control group which used western medicine of chinese patent medicine alone. TER : (RR: 4.75, CI 2.29 to 9.83, P<0.0001), TSS(dizziness) : (MD : 1.38, CI : 1.19 to 1.57, P<0.00001), TSS(hearing) : (MD : 1.11, CI : 0.97 to 1.28, P<0.00001), DHI : (MD : -8.24, CI : -10.73 to –5.76, P<0.00001). Conclusion : This study suggests that YGCGT is effective for meniere’s disease.