광용적맥파 비맥동성분에 의한 혈관경직도 변화 분석
Analysis of Arterial Stiffness Variation by Photoplethysmographic DC Component
2
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Assuming that photons absorbed by a vessel do not have acute variations, DC component reflect the basal blood volume (or diameter) before blood pulsation. Vascular stiffness and reflection is influenced by changes in basal blood volume (or diameter). This paper describes analysis of the characteristic variations of vascular stiffness, according to relative variations in DC components of the PPG signal (25-75%). For quantitative analysis, we have used parameters that were proposed previously, reflection and stiffness index, and the second derivative of PPG waveform, b/a and d/a. Significantly, the vascular stiffness and reflections were increased according to increase in DC component of the PPG signal for more than about 3% of baseline values. The systolic blood pressure were increased from 113.1 ± 13.18 to 116.2 ± 13.319 mmHg, about 2.76% (r = 0.991, p < 0.001) and the AC component of the PPG signal were decreased from 2.073 ± 2.287 to 1.973 ± 2.203 arbitrary unit, about 5.09% (r = −0.993, p < 0.001). It is separated by DC median and correlation analysis was performed for analyzing vascular characteristics according to instantaneous DC variations. There are significant differences between two correlation coefficients in separated data.
Abstract
Assuming that photons absorbed by a vessel do not have acute variations, DC component reflect the basal blood volume (or diameter) before blood pulsation. Vascular stiffness and reflection is influenced by changes in basal blood volume (or diameter). This paper describes analysis of the characteristic variations of vascular stiffness, according to relative variations in DC components of the PPG signal (25-75%). For quantitative analysis, we have used parameters that were proposed previously, reflection and stiffness index, and the second derivative of PPG waveform, b/a and d/a. Significantly, the vascular stiffness and reflections were increased according to increase in DC component of the PPG signal for more than about 3% of baseline values. The systolic blood pressure were increased from 113.1 ± 13.18 to 116.2 ± 13.319 mmHg, about 2.76% (r = 0.991, p < 0.001) and the AC component of the PPG signal were decreased from 2.073 ± 2.287 to 1.973 ± 2.203 arbitrary unit, about 5.09% (r = −0.993, p < 0.001). It is separated by DC median and correlation analysis was performed for analyzing vascular characteristics according to instantaneous DC variations. There are significant differences between two correlation coefficients in separated data.
참고문헌 (39)
- W. W. Nichols, "McDonald's blood flow in arteries : theoretic, experimental, and clinical principles, 5th ed" (2005), Oxford University Press
- D. Chemla, "Noninvasive assessment of arterial pressure", Curr Opin Crit Care, 14, pp.317~321 (2008)
- S. C. Millasseau, "Contour analysis of the photoplethysmographic pulse measured at the finger", J Hypertens, 24, pp.1449~1456 (2006)
- B. M. Pannier, "Methods and devices for measuring arterial compliance in humans", Am J Hypertens, 15, pp.743~753 (2002)
- L. A. Bortolotto, "Assessment of vascular aging and atherosclerosis in hypertensive subjects: second derivative of photoplethysmogram versus pulse wave velocity", Am J Hypertens, 13, pp.165~171 (2000)
- K. Takazawa, "Assessment of vasoactive agents and vascular aging by the second derivative of photoplethysmogram waveform", Hypertension, 32, pp.365~370 (1998)
- S. C. Millasseau, "Determination of age-related increases in large artery stiffness by digital pulse contour analysis", Clin Sci (Lond), 103, pp.371~377 (2002)
- P. J. Chowienczyk, "Photoplethysmographic assessment of pulse wave reflection: blunted response to endothelium- dependent beta2-adrenergic vasodilation in type II diabetes mellitus", J Am Coll Cardiol, 34 (1999)
- S. C. Millasseau, "The vascular impact of aging and vasoactive drugs: comparison of two digital volume pulse measurements", Am J Hypertens, 16, pp.467~472 (2003)
- e.J.G.Webster, "Design of Pulse Oximeters (Medical Science Series)", Physiological Measurement, 19 (1998)
- D. H. Bergel, "The static elastic properties of the arterial wall", J Physiol, 156, pp.445~457 (1961)
- J. Webster, "Design of pulse oximeters" (1997), Taylor & Francis
- J. Allen, "Microvascular blood flow and skin temperature changes in the fingers following a deep nspiratory gasp", Physiol Meas, 23, pp.365~373 (2002)
- R. Rauh, "Quantification of inspiratory-induced vasoconstrictive episodes: a comparison of laser Doppler fluxmetry and photoplethysmography", Clin Physiol Funct Imaging, 23, pp.344~348 (2003)
- J. Pan, "A real-time QRS detection algorithm", IEEE Transactions on Biomedical Engineering, pp.230~236 (1985)
- H. Shin, "Ideal Filtering Approach on DCT Domain for Biomedical Signals: Index Blocked DCT Filtering Method (IB-DCTFM)", Journal Of Medical Systems, 34(4), pp.741~753 (2010)
- H. Shin, "Adaptive threshold method for the peak detection of photoplethysmographic waveform", Computers in Biology and Medicine (2009)
- C. H. Chen, "Estimation of central aortic pressure waveform by mathematical transformation of radial tonometry pressure. Validation of generalized transfer function", Circulation, 95, pp.1827~1836 (1997)
- M.E.Safar, "Pulse pressure in essential hypertension: clinical and therapeutical implications", J Hypertens, 7, pp.769~776 (1989)
- J. Hashimoto, "Pulse wave velocity and the second derivative of the finger photoplethysmogram in treated hypertensive patients: their relationship and associating factors", J Hypertens, 20, pp.2415~2422 (2002)
- C. Z. Wang, "Comparison between reflection- mode photoplethysmography and arterial diameter change detected by ultrasound at the region of radial artery", Blood Press Monit, 15, pp.213~219 (2010)
- J. Weinmann, "Reflection photoplethysmography of arterial-blood-volume pulses", Med Biol Eng Comput, 15, pp.22~31 (1977)
- J. Hagblad, "A technique based on laser Doppler flowmetry and photoplethysmography for simultaneously monitoring blood flow at different tissue depths", Med Biol Eng Comput, 48, pp.415~422 (2010)
- J.Allen, "Photoplethysmography and its application in clinical physiological measurement", Physiol Meas, 28, pp.1~39 (2007)
- E. Zahedi, "Finger photoplethysmogram pulse amplitude changes induced by flow-mediated dilation", Physiol Meas, 29, pp.625~637 (2008)
- T. H. Westhoff, "Small artery elasticity assessed by pulse wave analysis is no measure of endothelial dysfunction", J Hypertens, 25, pp.571~576 (2007)
- D. G. Brillante, "Arterial stiffness indices in healthy volunteers using non-invasive digital photoplethysmography", Blood Press, 17, pp.116~123 (2008)
- M. J. Kool, "Diurnal pattern of vessel-wall properties of large arteries in healthy men", J Hypertens Suppl, 9, pp.108~109 (1991)
- W. W. Nichols, "Arterial elastance and wave reflection augmentation of systolic blood pressure: deleterious effects and implications for therapy", J Cardiovasc Pharmacol Ther, 6, pp.5~21 (2001)
- R. G. Asmar, "Improvement in blood pressure, arterial stiffness and wave reflections with a very-low-dose perindopril", indapamide combination in hypertensive patient: a comparison with atenolol, 2001, pp.38, 922~926
- G. M. London, "Mechanism(s) of selective systolic blood pressure reduction after a low-dose combination of perindopril", indapamide in hypertensive subjects: comparison with atenolol, 2004, pp.43, 92~99
- R. L. Armentano, "Assessment of elastin and collagen contribution to aortic elasticity in conscious dogs", Am J Physiol, 260, pp.1870~1877 (1991)
- T. Lnne, "Noninvasive measurement of diameter changes in the distal abdominal aorta in man", Ultrasound Med Biol, 18, pp.451~457 (1992)
- J. van den Akker, "Small artery remodeling: current concepts and questions", J Vasc Res, 47, pp.183~202 (2010)
- A. A. Stadler, "Blood viscosity and optimal hematocrit in narrow tubes", Biorheology, 27, pp.779~788 (1990)
- X. Chanudet, "The influence of anthropometric factors, hemorheologic parameters and the level of arterial pressure on pulse wave velocity", J Mal Vasc, 14, pp.15~18 (1989)
- 변미경, "지첨-족지 지수에 의한 동맥 혈관 특성화 연구", 의공학회지, 28(6), pp.777~785 (2007), 대한의용생체공학회
- 전석환, "자세변화에 따른 PWV 변화량의 평가", 의공학회지, 30(2), pp.129~134 (2009), 대한의용생체공학회
- 송상하, "맥파전달속도를 이용한 내중막 두께 추정에 관한 연구", 의공학회지, 30(5), pp.401~411 (2009), 대한의용생공학회