The Effect of Multi-tasking Exercise Intervention on Cognitive Function in Elderly and Cognitive Impairment Patients: a Pilot Multicenter Study
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Background and Purpose: The purpose of this study was to investigate the impact of multitasking exercise on cognitive and motor function in patients with mild cognitive impairment (MCI) and cognitive normal elderly (CNE). Methods: A total of 144 subjects were recruited from 14 regional dementia centers in Busan Metropolitan City. With the exception of 77 subjects unsuitable for the study, 67 subjects participated in the intervention. The Korean version of Mini-Mental State Examination for Dementia Screening (MMSE-DS), Subject Memory Complain Questionnaire (SMCQ), and the Korean version of the Short-Form Geriatric Depression Scale (SGDS-K) were used to determine changes in cognitive function and depressive symptoms pre-post intervention in patients with MCI and CNE, respectively. To observe changes in motor function, 5-chair sit to stand and 5-meter walking speed on the lower body strength and walking ability were also measured in both groups. Results: For the MCI group, changes in cognitive and depressive symptoms on the tasks of MMSE-DS (p=0.006), SMCQ (p=0.000), SGDS-K (p=0.000) and the result of the motor function analysis on the items of 5-chair sit to stand (p=0.000), normal speed (p=0.004) and maximal speed (p=0.002) of 5-meter walking speed (p<0.005). In the CNE group, all the items except MMSE-DS (p=0.068) and SGDS-K (p=0.095) showed statistically significant improvement. Conclusions: Multi-tasking exercise intervention, including exercise and cognitive tasks, may possibly improve the cognitive and motor function in patients with MCI and CNE.
Abstract
Background and Purpose: The purpose of this study was to investigate the impact of multitasking exercise on cognitive and motor function in patients with mild cognitive impairment (MCI) and cognitive normal elderly (CNE). Methods: A total of 144 subjects were recruited from 14 regional dementia centers in Busan Metropolitan City. With the exception of 77 subjects unsuitable for the study, 67 subjects participated in the intervention. The Korean version of Mini-Mental State Examination for Dementia Screening (MMSE-DS), Subject Memory Complain Questionnaire (SMCQ), and the Korean version of the Short-Form Geriatric Depression Scale (SGDS-K) were used to determine changes in cognitive function and depressive symptoms pre-post intervention in patients with MCI and CNE, respectively. To observe changes in motor function, 5-chair sit to stand and 5-meter walking speed on the lower body strength and walking ability were also measured in both groups. Results: For the MCI group, changes in cognitive and depressive symptoms on the tasks of MMSE-DS (p=0.006), SMCQ (p=0.000), SGDS-K (p=0.000) and the result of the motor function analysis on the items of 5-chair sit to stand (p=0.000), normal speed (p=0.004) and maximal speed (p=0.002) of 5-meter walking speed (p<0.005). In the CNE group, all the items except MMSE-DS (p=0.068) and SGDS-K (p=0.095) showed statistically significant improvement. Conclusions: Multi-tasking exercise intervention, including exercise and cognitive tasks, may possibly improve the cognitive and motor function in patients with MCI and CNE.
참고문헌 (23)
- Korean Dementia Observatory 2018, "Ministry of Health and Welfare", National Institute of Dementia, ~, pp.Report No.: NIDR-1802-0023 (2018)
- Petersen RC, "Mild cognitive impairment: clinical characterization and outcome", Arch Neurol, 56, pp.303~308 (1999)
- Gravitz L, "Drugs: a tangled web of targets", Nature, 475, pp.S9~S11 (2011)
- 신송재, "집단작업치료가 지역사회 거주 경증치매환자의 인지기능 및 우울에 미치는 영향", 대한작업치료학회지, 21(3), pp.45~60 (2013), 대한작업치료학회
- Brickman AM, "Successful Cognitive and Emotional Aging", pp.157~172 (2010), American Psychiatric Pub
- Barnett JH, "Cognitive reserve in neuropsychiatry", Psychol Med, 36, pp.1053~1064 (2006)
- Bossers WJ, "A 9-week aerobic and strength training program improves cognitive and motor function in patients with dementia: a randomized, controlled trial", Am J Geriatr Psychiatry, 23, pp.1106~1116 (2015)
- 이한숙, "치매노인을 위한 신체활동 프로그램이 인지기능에 미치는 영향 : 국내연구의 메타 분석", 대한물리의학회지, 11(2), pp.115~121 (2016), 대한물리의학회
- Gates N, "The effect of exercise training on cognitive function in older adults with mild cognitive impairment: a meta-analysis of randomized controlled trials", Am J Geriatr Psychiatry, 21, pp.1086~1097 (2013)
- Holtzer R, "fNIRS study of walking and walking while talking in young and old individuals", J Gerontol A Biol Sci Med Sci, 66, pp.879~887 (2011)
- Petersen RC, "Mild cognitive impairment: clinical characterization and outcome", Arch Neurol, 56, pp.303~308 (1999)
- 한지원, "치매 선별용 간이정신상태검사(Mini-Mental State Examination for Dementia Screening；MMSE-DS)와 단축형 MMSE-DS(SMMSE-DS)의 한국 노인 정상규준 연구", 노인정신의학, 14(1), pp.27~37 (2010), 대한노인정신의학회
- Yesavage JA, "Development and validation of a geriatric depression screening scale: a preliminary report", J Psychiatr Res, 17, pp.37~49 (1982)
- Sheikh JL, "Geriatric Depression Scale (GDS): recent evidence and development of a shorter version", Clin Gerontol, 5, pp.165~173 (1986)
- Bae JN, "Development of the Korean version of the Geriatric Depression Scale and its short form among elderly psychiatric patients", J Psychosom Res, 57, pp.297~305 (2004)
- Youn JC, "Development of the subjective memory complaints questionnaire", Dement Geriatr Cogn Disord, 27, pp.310~317 (2009)
- Winblad B, "Mild cognitive impairment--beyond controversies, towards a consensus: report of the International Working Group on Mild Cognitive Impairment", J Intern Med, 256, pp.240~246 (2004)
- Larrieu S, "Incidence and outcome of mild cognitive impairment in a population-based prospective cohort", Neurology, 59, pp.1594~1599 (2002)
- Sofi F, "Physical activity and risk of cognitive decline: a meta-analysis of prospective studies", J Intern Med, 269, pp.107~117 (2011)
- 김우영, "경도인지장애의 비약물요법에 대한 고찰", 동의신경정신과학회지, 22(3), pp.1~11 (2011), 대한한방신경정신과학회
- Erickson KI, "Training-induced functional activation changes in dual-task processing: an FMRI study", Cereb Cortex, 17, pp.192~204 (2007)
- 이병택, "이중과제 수행시의 간섭효과에 수반되는 신경기반: 산술연산과 기억인출간의 상호작용", 인지과학, 18(2), pp.159~178 (2007), 한국인지과학회[DOI]
- Panza F, "Late-life depression, mild cognitive impairment, and dementia: possible continuum?", Am J Geriatr Psychiatry, 18, pp.98~116 (2010)