Emerging of Explosive Speech after Olanzapine in Multiple System Atrophy Patient
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Background: Cerebellum has an important role in sensorimotor control including speech. Multiple system atrophy (MSA) is a sporadic and rapidly progressive neurodegenerative disorder that presents with autonomic failure in combination with Parkinsonism or cerebellar ataxia. Case Report: We report a case of MSA-cerebellum subtype associated with emergence of irreversible explosive speech following olanzapine therapy. Conclusions: Further investigation into speech problems in MSA according to subtype and disease severity is needed, and side effects of olanzapine therapy should also be considered.
Abstract
Background: Cerebellum has an important role in sensorimotor control including speech. Multiple system atrophy (MSA) is a sporadic and rapidly progressive neurodegenerative disorder that presents with autonomic failure in combination with Parkinsonism or cerebellar ataxia. Case Report: We report a case of MSA-cerebellum subtype associated with emergence of irreversible explosive speech following olanzapine therapy. Conclusions: Further investigation into speech problems in MSA according to subtype and disease severity is needed, and side effects of olanzapine therapy should also be considered.
참고문헌 (13)
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