Clinical and Demographic Predictors of Adverse Outcomes in Caregivers of Patients with Dementia
2
조회
0
다운로드
1
인용
0
참고문헌
키워드
초록
Background and Purpose: We aimed to elucidate independent predictors of adverseoutcomes in caregivers of patients with dementia using readily available clinical anddemographic data of patients with dementia and their caregivers. Methods: We reviewed patient-caregiver data from the Clinical Research Center for Dementiaof South Korea and Caregivers of Alzheimer Disease Research study. The clinical factorsof the patients and the demographics of both patients and caregivers were used to predictadverse outcomes for caregivers. Correlation and linear regression analyses were performed. Results: We enrolled 454 patients and their caregivers for the present study. The generalburden for the caregiver was higher amongst female caregivers, patients with furtherdecreased the level of activities of daily living (ADL), patients with more abnormal behavior,or younger patients. The time spent by the caregivers was more in cases of patients withhigher Caregiver Administered Neuropsychiatric Inventory scores, younger patients and forpatients with decreased level of ADL. Depression amongst caregivers was more prominent inpatients with higher Clinical Dementia Rating Sum of Boxes scores. Physical health-relatedquality of life (HRQoL) was lower in female caregivers, more physically affected patients, andolder caregivers. Lastly, mental HRQoL was lower in younger, more physically affected, and inpatients with abnormal behaviors. Conclusions: Clinical and demographic characteristics of patients and caregivers predictadverse outcomes for caregivers. Therefore, these factors should be considered to providesupport to both patients and their caregivers.
Abstract
Background and Purpose: We aimed to elucidate independent predictors of adverseoutcomes in caregivers of patients with dementia using readily available clinical anddemographic data of patients with dementia and their caregivers. Methods: We reviewed patient-caregiver data from the Clinical Research Center for Dementiaof South Korea and Caregivers of Alzheimer Disease Research study. The clinical factorsof the patients and the demographics of both patients and caregivers were used to predictadverse outcomes for caregivers. Correlation and linear regression analyses were performed. Results: We enrolled 454 patients and their caregivers for the present study. The generalburden for the caregiver was higher amongst female caregivers, patients with furtherdecreased the level of activities of daily living (ADL), patients with more abnormal behavior,or younger patients. The time spent by the caregivers was more in cases of patients withhigher Caregiver Administered Neuropsychiatric Inventory scores, younger patients and forpatients with decreased level of ADL. Depression amongst caregivers was more prominent inpatients with higher Clinical Dementia Rating Sum of Boxes scores. Physical health-relatedquality of life (HRQoL) was lower in female caregivers, more physically affected patients, andolder caregivers. Lastly, mental HRQoL was lower in younger, more physically affected, and inpatients with abnormal behaviors. Conclusions: Clinical and demographic characteristics of patients and caregivers predictadverse outcomes for caregivers. Therefore, these factors should be considered to providesupport to both patients and their caregivers.
참고문헌 (38)
- Zarit SH, "Relatives of the impaired elderly: correlates of feelings of burden", Gerontologist, 20, pp.649~655 (1980)
- Etters L, "Caregiver burden among dementia patient caregivers: a review of the literature", J Am Acad Nurse Pract, 20, pp.423~428 (2008)
- Brodaty H, "Psychosocial effects on carers of living with persons with dementia", Aust N Z J Psychiatry, 24, pp.351~361 (1990)
- Hazzan AA, "The association between caregiver well-being and care provided to persons with Alzheimer's disease and related disorders", BMC Res Notes, 9, pp.344~ (2016)
- Davis KL, "The Caregiver Activity Survey (CAS): development and validation of a new measure for caregivers of persons with Alzheimer's disease", Int J Geriatr Psychiatry, 12, pp.978~988 (1997)
- Farina N, "Factors associated with the quality of life of family carers of people with dementia: a systematic review", Alzheimers Dement, 13, pp.572~581 (2017)
- Covinsky KE, "Patient and caregiver characteristics associated with depression in caregivers of patients with dementia", J Gen Intern Med, 18, pp.1006~1014 (2003)
- Springate BA, "Dimensions of caregiver burden in dementia: impact of demographic, mood, and care recipient variables", Am J Geriatr Psychiatry, 22, pp.294~300 (2014)
- Kim H, "Predictors of caregiver burden in caregivers of individuals with dementia", J Adv Nurs, 68, pp.846~855 (2012)
- Torrisi M, "Neuropsychiatric symptoms in dementia may predict caregiver burden: a Sicilian exploratory study", Psychogeriatrics, 17, pp.103~107 (2017)
- Beerens HC, "Factors associated with quality of life of people with dementia in long-term care facilities: a systematic review", Int J Nurs Stud, 50, pp.1259~1270 (2013)
- Kim SK, "Influence of personality on depression, burden, and health-related quality of life in family caregivers of persons with dementia", Int Psychogeriatr, 29, pp.227~237 (2017)
- Yoon KH, "The moderating effect of religiosity on caregiving burden and depressive symptoms in caregivers of patients with dementia", Aging Ment Health, 22, pp.141~147 (2018)
- 박희경, "Clinical Characteristics of a Nationwide Hospital-based Registry of Mild-to-Moderate Alzheimer’s Disease Patients in Korea: A CREDOS (Clinical Research Center for Dementia of South Korea) Study", Journal of Korean Medical Science, 26(9), pp.1219~1226 (2011), 대한의학회
- Kang Y, "A validity study on the Korean mini-mental state examination (K-MMSE) in dementia patients", J Korean Neurol Assoc, 15, pp.300~308 (1997)
- Morris JC, "The Clinical Dementia Rating (CDR): current version and scoring rules", Neurology, 43, pp.2412~2414 (1993)
- 구형모, "일상활동평가-복합(Seoul-Instrumental Activities of Daily Living ; S-IADL)의 신뢰도 및 타당도 연구", 신경정신의학, 43(2), pp.189~199 (2004), 대한신경정신의학회
- Choi SH, "Korean version of the neuropsychiatric inventory: a scoring tool for neuropsychiatric disturbance in dementia patients", J Korean Med Sci, 15, pp.609~615 (2000)
- 이형석, "치매 환자 보호자의 스트레스 평가: 기억 및 행동문제점검- 개정판(Revised-Memory and Behavior Problem Checklist: R-MBPC)과 부담조사(Burden Interview: BI)의 신뢰도 및 타당도", Korean Journal of Clinical Psychology, 23(4), pp.1029~1050 (2004), 한국임상심리학회
- 김재민, "지역사회거주 치매노인 부양자를 대상으로 한 ‘한국어판 부양자 활동 조사(CAS-K)'의 개발", 대한신경과학회지, 22(4), pp.322~327 (2004), 대한신경과학회
- Hahn HM, "A standardization study of Beck Depression Inventory in Korea", J Korean Neuropsychiatr Assoc, 25, pp.487~500 (1986)
- Han CW, "Development of the Korean version of short-form 36-item health survey: health related QOL of healthy elderly people and elderly patients in Korea", Tohoku J Exp Med, 203, pp.189~194 (2004)
- Rinaldi P, "Predictors of high level of burden and distress in caregivers of demented patients: results of an Italian multicenter study", Int J Geriatr Psychiatry, 20, pp.168~174 (2005)
- Serrano-Aguilar PG, "Impact on health-related quality of life and perceived burden of informal caregivers of individuals with Alzheimer's disease", Neuroepidemiology, 27, pp.136~142 (2006)
- Akpınar B, "Effects of gender on burden among caregivers of Alzheimer's patients", J Nurs Scholarsh, 43, pp.248~254 (2011)
- Kim MD, "Caregiver burden among caregivers of Koreans with dementia", Gerontology, 55, pp.106~113 (2009)
- Park M, "Multidimensional determinants of family caregiver burden in Alzheimer's disease", Int Psychogeriatr, 27, pp.1355~1364 (2015)
- Sussman T, "The influence of community-based services on the burden of spouses caring for their partners with dementia", Health Soc Work, 34, pp.29~39 (2009)
- Marin DB, "The Caregiver Activity Survey (CAS): longitudinal validation of an instrument that measures time spent caregiving for individuals with Alzheimer's disease", Int J Geriatr Psychiatry, 15, pp.680~686 (2000)
- Andreakou MI, "Assessment of health-related quality of life for caregivers of Alzheimer's disease patients", Int J Alzheimers Dis, 2016, pp.9213968~ (2016)
- Bruvik FK, "The quality of life of people with dementia and their family carers", Dement Geriatr Cogn Disord, 34, pp.7~14 (2012)
- Markowitz JS, "Health-related quality of life for caregivers of patients with Alzheimer disease", Alzheimer Dis Assoc Disord, 17, pp.209~214 (2003)
- Freyne A, "Burden in carers of dementia patients: higher levels in carers of younger sufferers", Int J Geriatr Psychiatry, 14, pp.784~788 (1999)
- Jones C, "Health economics research into supporting carers of people with dementia: a systematic review of outcome measures", Health Qual Life Outcomes, 10, pp.142~ (2012)
- Kaiser S, "The psychosocial impact of young onset dementia on spouses", Am J Alzheimers Dis Other Demen, 21, pp.398~402 (2006)
- van Vliet D, "Impact of early onset dementia on caregivers: a review", Int J Geriatr Psychiatry, 25, pp.1091~1100 (2010)
- Ankri J, "Beyond the global score of the Zarit Burden Interview: useful dimensions for clinicians", Int J Geriatr Psychiatry, 20, pp.254~260 (2005)
- Bergvall N, "Relative importance of patient disease indicators on informal care and caregiver burden in Alzheimer's disease", Int Psychogeriatr, 23, pp.73~85 (2011)