임상화학 분야 정량검사 결과의 단위 및 자릿수 보고 국내현황 고찰
Current Status of Reporting Units and Unit Sizes of Quantitative Test Results of Clinical Chemistry in Korea
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배경: 정량 검사 결과의 단위와 소수점 아래 자릿수는 각 검사실별로 다양하여, 아직 표준화나 일치화가 되지 않은 경우가 대부분이다. 본 연구에서는 임상화학 분야에서 국내 임상 검사실에서 사용하는 각 정량 검사 결과의 단위와 소수점 아래 자릿수에 대한 현황을 조사하고 표준화된 단위 및 자릿수에 대해 제안하고자 하였다. 방법: 대한임상검사정도관리협회 신빙도 조사사업과 미국병리협회 조사 자료 및 교과서(Tietz 제6판과 Henry 제24판)을 고찰하였다. 그리고 대한임상화학회 회원들을 대상으로 온라인 설문 플랫폼을 사용하여 총 99개 검사항목에 대한 설문조사를 실시하였고, 총 99기관이 응답하였다. 일부 항목에 대해 표준화된 소수점 아래 자릿수 제안을 위한 모의 실험을 시행하였다. 결과: 54종목(54.5%)에서 사용 단위가 4가지 참고자료 모두에서 일치하였고, 28종목(28.3%)에서 자릿수가 일치하였다. 설문조사 결과, 단위의 경우 최빈도 사용 단위를 사용하는 기관의 비율이 80% 이상인 항목이 93개(93.9%)였으나, 자릿수의 경우 30곳 (30.3%)에 불과하였다. 자릿수 제안을 위한 모의 실험 결과 참가 검사실 3곳 모두 현재 사용 중인 자릿수가 적합한 것으로 나타났다. 결론: 본 연구는 임상화학 분야 99개 정량 검사 항목의 결과보고 단위 및 소수점 아래 자릿수에 대한 문헌 고찰과 일부 모의 실험과 함께 국내 현황을 조사한 최초의 연구이다. 본 연구 자료가 앞으로 국내외의 정량 검사 결과보고 단위 및 소수점 아래 자릿수 설정에 있어서 기초 자료로 활용될 것으로 기대된다.
Abstract
Background: The units and unit sizes of quantitative test results vary between laboratories and have not yet been standardized or harmonized in most cases. This study aimed to investigate the current status of units and unit sizes of clinical chemistry in Korea and propose standardized ones. Methods: The Korean Association of External Quality Assessment Service and College of American Pathologists survey data and textbooks (Tietz 6th ed. and Henry 24th ed.) were reviewed. Members of the Korean Society of Clinical Chemistry were surveyed on 99 items using an online sur vey platform, and a total of 99 institutions responded. For some items, simulations were conducted for standardized unit size proposals. Results: The units were consistent in all four references for a total of 54 items (54.5%), whereas, the unit sizes were consistent for 28 items (28.3%). In the questionnaire, 93 items (93.9%) accounted for more than 80% of institutions utilizing the most frequently used unit but only 30 items (30.3%) for unit sizes. As a result of the simulation for the number of digits proposal, it was found that the number of digits currently in use was acceptable for all three participating laboratories. Conclusions: To the best of our knowledge, this is the first study to investigate the current situation and simulation of the units and unit sizes in clinical chemistry in Korea through a literature review. These data are expected to be used as a basis for the setting of units and unit sizes for reporting quantitative test results in the future.
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