세균성 복막염 환자에서 분리된 Enterococcus pallens의 국내 최초 증례
First Case of Spontaneous Bacterial Peritonitis Caused by Enterococcus pallens in Korea
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Enterococcus pallens는 노란 색소침착을 보이는 enterococci로현재까지 캐나다 복막염 환자의 복막액에서 분리된 4건의 보고만이 존재한다. 본 증례에서 저자들은 국내에서 최초로 분리된 E. pallens 균종에 대해 보고하고자 한다. 간경화 과거력이 있는 71세남자 환자가 복수 양 증가로 응급실을 통해 입원하였다. 복막액 세균배양에서 그람양성알균이 관찰되었다. 혈액한천배지에서 계대배양 하였을 때 회색의 작은 알파 용혈성 집락을 형성하였으며, 노란 색소침착이 관찰되었다. 해당 균주는 MALDI Biotyper (Bruker Daltonics, Germany)를 통한 동정에서 E. pallens로 확인되었으며, 16S rRNA 염기서열분석에서도 동일한 동정 결과를 보였다. VITEK 2 GP, P600 panel (bioMérieux, France)을 이용한 항균제 감수성 검사에서 대부분의 항균제에 감수성을 보이는 것으로 나타났다. 본 연구를 통해 저자들은 국내 최초로 환자에서 분리된 E. pallens를 보고하고, 균주의 동정 과정과 특성에 관한 정보를 공유하고자 한다.
Abstract
Enterococcus pallens is a yellow-pigmented Enterococcus species and to date, only four cases of its isolation have been reported. All previous strains were isolated from ascitic fluid samples from Canadian patients with peritonitis. Here, we report the first strain of E. pallens isolated in Korea. A 71-year-old male patient with liver cirrhosis visited the emergency department due to an increased ascitic fluid volume. Gram-positive cocci were detected in ascitic fluid culture. The strain showed small, gray, alpha-hemolytic colonies with yellow pigmentation on a blood agar plate. The strain was identified as E. pallens using a MALDI Biotyper (Bruker Daltonics, Germany) and 16S rRNA gene sequencing. The strain showed susceptibility to most antimicrobials on an antimicrobial sensitivity test using a VITEK 2 GP, P600 panel (bioMérieux, France). This case report provides detailed information on the steps taken to identify E. pallens and its characteristics, offering valuable insights for further identification.
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