Management of Psoriasis through Unani Medicine: a Case Study
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Psoriasis is a chronic inflammatory skin disease clinically characterized by erythematous, sharply demarcated papules and rounded plaques covered by silvery white micaceous scales. It affects about 1-3% of the world’s population. Although considerable advances have been made in the management of psoriasis in recent years, the disease remains incurable. Current treatment does not affect disease activity, and relapse occurs quickly after cessation of treatment. Moreover, topical and systemic conventional therapies used in the management of psoriasis are associated with adverse effects. In Unani system of medicine, psoriasis is known as Taqashshur al-Jild, which is caused by predominance of black bile and characterised by scaling of skin. Various topical as well as systemic Unani formulations are effectively used in the management of psoriasis. This case study was aimed to evaluate the efficacy of Unani formulations, Itrīfal Shāhtra and Marham Ḥinā in the management of psoriasis. A 49-year-old male patient presenting with psoriasis came to the OPD of National Research Institute of Unani Medicine for Skin Disorders, Hyderabad. Treatment was given to the patient for a period of 12 weeks. PASI score was significantly reduced from 40.5 at baseline to 2.2 after treatment. Unani formulations were found safe and effective in the management of Psoriasis as assessed by validated scales.
Abstract
Psoriasis is a chronic inflammatory skin disease clinically characterized by erythematous, sharply demarcated papules and rounded plaques covered by silvery white micaceous scales. It affects about 1-3% of the world’s population. Although considerable advances have been made in the management of psoriasis in recent years, the disease remains incurable. Current treatment does not affect disease activity, and relapse occurs quickly after cessation of treatment. Moreover, topical and systemic conventional therapies used in the management of psoriasis are associated with adverse effects. In Unani system of medicine, psoriasis is known as Taqashshur al-Jild, which is caused by predominance of black bile and characterised by scaling of skin. Various topical as well as systemic Unani formulations are effectively used in the management of psoriasis. This case study was aimed to evaluate the efficacy of Unani formulations, Itrīfal Shāhtra and Marham Ḥinā in the management of psoriasis. A 49-year-old male patient presenting with psoriasis came to the OPD of National Research Institute of Unani Medicine for Skin Disorders, Hyderabad. Treatment was given to the patient for a period of 12 weeks. PASI score was significantly reduced from 40.5 at baseline to 2.2 after treatment. Unani formulations were found safe and effective in the management of Psoriasis as assessed by validated scales.
참고문헌 (35)
- Ali H, "Unani Management of Taqashshure Jild (Psoriasis): A case report", Sch J Appl Med Sci, 3(2B), pp.677~681 (2015)
- Āmlī, "Muḥammad ibn Maḥmūd. Mūjaz", pp.219~, Maṭba‘Munshī Naval Kishore
- Hijri, "National Formulary of Unani Medicine, Part-VI", pp.78~ (2011), CCRUM, Dept. of AYUSH, Ministry of Health & Family Welfare
- Arzānī, Ḥakīm Muḥammad Akbar, "Ḥakīm Muḥammad Akbar. Mīzān al-Ṭibb", pp.257~ (2001), Idārā Kitāb al-Shifā
- Arzānī, Ḥakīm Muḥammad Akbar, "Ṭibb-i-Akbar", pp.739~742 (1993), Faisal Publications
- Baghdādī, "‘Ali ibn Hubal. Kitāb al-Mukhtārāt fi’l Ṭibb. Urdu translation. Volume 2", pp.83~ (2005), CCRUM, Ministry of Health & Family Welfare
- Burge S, "Oxford Handbook of Medical Dermatology", pp.189~209 (2016), Oxford University Press
- Buslau M, "Cardiovascular complications of psoriasis: Does obstructive sleep apnoea play a role?", Acta Derm Venereol, 79(3), pp.234~ (1999)
- Carvalho AVE, "Psoriasis comorbidities: complications and benefits of immunobiological treatment", An Bras Dermatol, 91(6), pp.781~789 (2016)
- Danielsen K, "Is the prevalence of psoriasis increasing? A 30-year follow-up of a population-based cohort", Br J Dermatol, 168, pp.1303~1310 (2013)
- DiPiro JT, "Pharmacotherapy: A Pathophysiologic Approach", pp.4772~4841 (2020), McGraw-Hill Education
- Dreiher J, "Psoriasis and chronic obstructive pulmonary disease: A casecontrol study", Br J Dermatol, 159(4), pp.956~960 (2008)
- Gelfand JM, "The risk of lymphoma in patients with psoriasis", J Invest Dermatol, 126(10), pp.2194~2201 (2006)
- Gibbs S, "Skin disease and socioeconomic conditions in rural Africa: Tanzania", Int J Dermatol, 35(9), pp.633~639 (1996)
- Gisondi P, "Nonalcoholic fatty liver disease in patients with chronic plaque psoriasis", J Hepatol, 51(4), pp.758~764 (2009)
- Ibn Zuhr, "Urdu translation", pp.204~205 (1986), CCRUM, Ministry of Health & Family Welfare
- Jīlānī, Ḥakīm Ghulām, "Makhzan al-Ḥikmat", pp.698~699 (1996), Ejaz Publishing House
- Khān, Ḥakīm Muḥammad A‘ẓam, "Iksīr-i-A‘ẓam (Fārsī)", pp.511~, Maṭba‘ Niẓāmī
- Hijri. Khān, "Ḥakīm Muḥammad Akmal. Qarābādīn-ī ‘Āzam wa Akmal. Urdu Translation", pp.7~ (2005), CCRUM, Dept. of AYUSH, Ministry of Health & Family Welfare
- Majūsī, ‘Ali ibn ‘Abbās, "Kāmil al-Ṣanā‘a al-Ṭibbiyya Volume I-II", pp.431~433 (2010), Idārā Kitāb al-Shifā
- Menter A, "Guidelines of care for the management of psoriasis and psoriatic arthritis. Section 3. Guidelines of care for the management and treatment of psoriasis with topical therapies", J Am Acad Dermatol, 60(4), pp.643~659 (2009)
- Millard TP, "Bone mineral density of patients with chronic plaque psoriasis", Clin Exp Dermatol, 26(5), pp.446~448 (2001)
- Nestle FO, "Psoriasis", N Engl J Med, 361(5), pp.496~509 (2009)
- Nickoloff BJ, "Response of murine and normal human skin to injection of allogeneic blood-derived psoriatic immunocytes: detection of T cells expressing receptors typically present on natural killer cells, including CD94, CD158, and CD161", Arch Dermatol, 135(5), pp.546~552 (1999)
- Papadakis MA, "Current Medical Diagnosis & Treatment", pp.115~117 (2019), McGraw-Hill Education
- Peternel S, "Treatment of Severe Psoriasis with Infliximab:Report of Two Cases", Acta Dermatovenerol Croat, 17(3), pp.204~206 (2009)
- Qarshī, Ḥakīm Muḥammad Ḥasan, "Jame-ul-Ḥikmat. Vol. 2", pp.1005~ (2011), Idārā Kitāb al-Shifā
- Rahman M, "Classical to current approach for treatment of psoriasis: a review", Endocr Metab Immune Disord Drug Targets, 12(3), pp.287~302 (2012)
- Rāzī, Abū Bakr Muḥammad ibn Zakariyya, "Kitāb al-Fākhir fi’l Ṭibb (Arabic). Part-1", pp.28~ (2005), CCRUM, Ministry of Health & Family Welfare
- Rāzī, Abū Bakr Muḥammad ibn Zakariyya, "Kitāb al-Ḥāwī fi’l Ṭibb Vol-23", pp.61~62 (1994), Saba Publishers
- Rāzī, Abū Bakr Muḥammad ibn Zakariyya, "Kitāb al-Manṣūrī. Urdu translation", pp.200~ (1991), CCRUM, Ministry of Health & Family Welfare
- Sehgal, VN, "Textbook of Clinical Dermatology", pp.135~148 (2011), Jitendar P Vij, Jaypee Brothers Medical Publishers
- Sheu JJ, "Psoriasis is associated with an increased risk of parkinsonism: a population-based 5-year follow-up study", J Am Acad Dermatol, 68(6), pp.992~999 (2013)
- Ṭabarī, Abu’l Ḥasan Aḥmad ibn Muḥammad, "Mu‘ālajāt alBuqrāṭiyya (Urdu translation). Vol-2", pp.153~155 (1997), CCRUM, Ministry of Health & Family Welfare
- Valia RG, "IADVL Textbook of Dermatology Vol. 1", pp.1025~1055 (2010), Bhalani Publishing House