원내 DUR 프로그램을 통한 신기능 변화에 따른 약사의 중재활동

Abstract

The kidney is an excretory organ that eliminates substances from outside or produced in the body via renal excretory process. In addition, the kidney has an important role in the process that eliminates drugs or their metabolites. Thus, impaired renal function may induce the change in drug effects or adverse effects. Therefore, dosage or dosing interval adjustment is important in the consideration of impaired renal function. In Severance hospital, there are many in patients with severe disease or who are receiving a number of drugs. The frequency of drug usage that needs taking into account the patients’renal function is also high. Thus, it is recommended that dosage or dosing interval adjustment needs to depend on drug guidelines and the role of pharmacists is important in intervention. This study represented the results of drug evaluation using Severance hospital’s DUR (Drug Utilization Review) program by pharmacists from January 1 to January 31, 2011. The result represents that appropriate drug usage was 49.0% taking into account patients’renal function. Based on this study, we suggest that doctors should monitor drug usage more carefully in renal impairment and pharmacists should intervene more actively using the DUR program.