외과계 중환자실 전담약사 유무에 따른 중재활동 변화 및 회피비용 분석
The Effects of Designated Pharmacist on Intervention and Cost Avoidance in the Surgical Intensive Care Unit
1
조회
0
다운로드
5
인용
0
참고문헌
키워드
초록
Background : The prevention of adverse drug events had been documented by pharmacists in critically ill patients. The purpose of this study was to evaluate the effect of the designated pharmacists’interventions, acceptance rate and cost avoidance in the surgical intensive care unit (SICU) at a tertiary hospital in Korea. Methods : A retrospective observational study was conducted using electronic medical records. The frequencies of the interventions, acceptance rate, and type of interventions were observed. Cost avoidance was calculated from the potential benefit or harm of the pharmacists’recommendations and the expected extension of hospitalization without a pharmacist intervention. Results : The frequencies of the intervention increased from 0.16% to 0.56%(p 0.001) and the acceptance rate of the pharmacist intervention increased from 69% to 89%(p 0.05). Since the introduction of the designated pharmacist, pharmacists’interventions have expanded into the clinical field, such as total parenteral nutrition (TPN), drug recommendations and sharing treatment plans, possible adverse drug reactions, and therapeutic drug monitoring (TDM). The calculated avoidance cost per month associated with a designated pharmacists’intervention was 9,335,382 won/month. Conclusion : With the designated pharmacist, the frequencies of the pharmacists’intervention and the acceptance rate of interventions among the medical team increased. The cost avoidance from the pharmacists’interventions imply a potential economic advantage; therefore, it is necessary to evaluate the further economic effects of the pharmacists’intervention.
Abstract
Background : The prevention of adverse drug events had been documented by pharmacists in critically ill patients. The purpose of this study was to evaluate the effect of the designated pharmacists’interventions, acceptance rate and cost avoidance in the surgical intensive care unit (SICU) at a tertiary hospital in Korea. Methods : A retrospective observational study was conducted using electronic medical records. The frequencies of the interventions, acceptance rate, and type of interventions were observed. Cost avoidance was calculated from the potential benefit or harm of the pharmacists’recommendations and the expected extension of hospitalization without a pharmacist intervention. Results : The frequencies of the intervention increased from 0.16% to 0.56%(p 0.001) and the acceptance rate of the pharmacist intervention increased from 69% to 89%(p 0.05). Since the introduction of the designated pharmacist, pharmacists’interventions have expanded into the clinical field, such as total parenteral nutrition (TPN), drug recommendations and sharing treatment plans, possible adverse drug reactions, and therapeutic drug monitoring (TDM). The calculated avoidance cost per month associated with a designated pharmacists’intervention was 9,335,382 won/month. Conclusion : With the designated pharmacist, the frequencies of the pharmacists’intervention and the acceptance rate of interventions among the medical team increased. The cost avoidance from the pharmacists’interventions imply a potential economic advantage; therefore, it is necessary to evaluate the further economic effects of the pharmacists’intervention.
참고문헌 (32)
- Moyen E, "Clinical review: Medication errors in critical care:review", Crit Care, 12(2), pp.208~215 (2008)
- Camire E, "Medication errors in critical care : risk factors, prevention and disclosure", CMAJ, 180(9), pp.936~943 (2009)
- Kaboli PJ, "Clinical pharmacists and inpatient medical care : a systematic review", Arch Intern Med, 166(9), pp.955~964 (2006)
- Pronovost P, "Medication reconciliation : a practical tool to reduce the risk of medication errors", J Crit Care, 18(4), pp.201~205 (2003)
- Vargas E, "Effect of adverse drug reactions on length of stay in surgical intensive care units", Crit Care Med, 31(3), pp.694~698 (2003)
- Cullen DJ, "Preventable adverse drug events in hospitalized patients : a comparative study of intensive care and general care units", Crit Care Med, 25(8), pp.1289~1297 (1997)
- Kopp BJ, "Medication errors and adverse drug events in an intensive care unit : direct observation approach for detection", Crit Care Med, 34(2), pp.415~425 (2006)
- Thomas EJ, "Incidence and types of preventable adverse events in elderly patients : population based review of medical records", Bmj, 320(7237), pp.741~744 (2000)
- Thomsen LA, "Systematic review of the incidence and characteristics of preventable adverse drug events in ambulatory care", Ann. Pharmacother, 41(9), pp.1411~1426 (2007)
- Von Laue NC, "The epidemiology of preventable adverse drug events: a review of the literature", Wien. Klin. Wochenschr, 115(12), pp.407~415 (2003)
- Leape LL, "Pharmacist participation on physician rounds and adverse drug events in the intensive care unit", JAMA, 282(3), pp.267~270 (1999)
- MacLaren R, "Critical care pharmacy services in United States hospitals", Annals of Pharmacotherapy, 40(4), pp.612~618 (2006)
- Kopp BJ, "Cost implications of and potential adverse events prevented by interventions of a critical care pharmacist", Am J Health Syst Pharm, 64(23), pp.2483~2487 (2007)
- Kaye J, "Critical care bug team : a multi-disciplinary team approach to reducing ventilatorassociated pneumonia", Am J Infection Control, 28(2), pp.197~201 (2000)
- Stenger K, "Moving to evidence-based practice for pain management in the critical care setting", Crit Care Nurs Clin North Am, 13(2), pp.319~327 (2001)
- Dasta JF, "Evolving role of the pharmacist in the critical care environment", J Clin Anesth, 8(3), pp.S99~S102 (1996)
- Dasta JF, "National survey of critical-care pharmaceutical services", Am J Hosp Pharm, 46(11), pp.2308~2312 (1989)
- Marshall J, "Impact of a clinical pharmacist-enforced intensive care unit sedation protocol on duration of mechanical ventilation and hospital stay", Critical care medicine, 36(2), pp.427~433 (2008)
- Kane SL, "The impact of critical care pharmacists on enhancing patient outcomes", Intensive Care Med, 29(5), pp.691~698 (2003)
- Mutnick AH, "Cost savings and avoidance from clinical interventions", Am J Health Syst Pharm, 54(4), pp.392~396 (1997)
- The conceptual Framework for the International Classification for Patient Safety: Final Technical Report, "World Health Organization", WHO, 1~149 (2009)
- 손유민, "중환자 약료", J. Kor. Soc. Health-Syst. Pharm, 33(2), pp.172~183 (2016)
- Hunfeld NG, "Pharmacist clinical interventions in the ICU", Critical Care, 14(Suppl 1), pp.P447~ (2010)
- Fideles GMA, "Pharmacist recommenda-tions in an intensive care unit: three-year clinical activities", Rev. bras. ter. Intensive, 27(2), pp.149~154 (2015)
- Rudis MI, "Position paper on critical care pharmacy services", Pharmacotherapy, 20(11), pp.1400~1406 (2000)
- 김영신, "중환자실 약사의 역할", Kor. Soc. Health-Syst. Pharm, 28(2), pp.105~110 (2011)
- 정정원, "외과계 중환자실 약사의 처방중재효과 평가", 병원약사회지, 31(4), pp.908~918 (2014), 한국병원약사회
- 강민경, "외과계중환자실 담당약사의 약물유해반응 예방에 대한 처방중재효과", Acute and Critical Care, 28(1), pp.17~24 (2013), 대한중환자의학회
- Joo-won Chung, "Preliminary study for Economy evaluation of clinical pharmacist intervention", J. Kor. Soc. Health-Syst. Pharm, 28(4), pp.327~336 (2011)
- 서예원, "노인 약물평가 및 경제적 효과분석", J. Kor. Soc. Health-Syst. Pharm, 31(6), pp.1067~1073 (2014)
- Bond CA, "Interrelationships among Mortality rates, drug costs, total cost of care, and length of stay in United States hospitals : Summary and recommendations for clinical pharmacy services and staffing", Pharmacotherapy, 21(2), pp.129~141 (2001)
- Knaus WA, "APACHE II : a severity of disease classification system", Critical Care Medicine, 13(10), pp.818~829 (1985)
